Ace2 ELISA Kit for Mouse(Mus musculus) | EIAab.comAce2 ELISA Kit for Mouse(Mus musculus)

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Ace2 (Gene name),

Angiotensin-converting enzyme 2 (Protein name ), ACE2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ace2;

Protein name:

Angiotensin-converting enzyme 2;

Alternative:

ACE-related carboxypeptidase;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Weakly interacts with SARS-CoV S protein.

Function:

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. May have a protective role in acute lung injury.

Subcellular Location:

Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

805

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

805:

AQTSF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8R0I0

Pfam:

PF01401

KEGG:

mmu:70008

UniGene:

Mm.13451

String:

Q8R0I0

Uniprot:

Q8R0I0

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ELISA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

E1886h

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96T

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ELISA Kit for Mouse Angiotensin-converting enzyme 2

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E1886r

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96T

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ELISA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

E1886m

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ELISA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

E1886b

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Packing:

96T

CLIA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

U1886r

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96T

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CLIA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

U1886h

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Looking for manual.

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96T

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CLIA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

U1886m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Angiotensin-converting enzyme 2

Cat.:

U1886b

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Packing:

96T

Polyclonal Antibody for Mouse Angiotensin-converting enzyme 2

Cat.:

P1886Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Angiotensin-converting enzyme 2

Cat.:

P1886Rb-m

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40ug/0.2ml

Polyclonal Antibody for Mouse Angiotensin-converting enzyme 2

Cat.:

P1886Rb-r

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Angiotensin-converting enzyme 2

Protein for Mouse Angiotensin-converting enzyme 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning, mRNA expression, and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2)."
Komatsu T. , Suzuki Y. , Imai J. , Sugano S. , Hida M. , Tanigami A. , Muroi S. , Yamada Y. , Hanaoka K.
DNA Seq.13:217-220(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: FVB/N.
tissue: Kidney.
3.

"Angiotensin-converting enzyme 2 is an essential regulator of heart function."
Crackower M.A. , Sarao R. , Oudit G.Y. , Yagil C. , Kozieradzki I. , Scanga S.E. , Oliveira-dos-Santos A.J. , da Costa J. , Zhang L. , Pei Y. , Scholey J. , Ferrario C.M. , Manoukian A.S. , Chappell M.C. , Backx P.H. , Yagil Y. , Penninger J.M.
Nature417:822-828(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
4.

"Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins."
Donoghue M. , Wakimoto H. , Maguire C.T. , Acton S. , Hales P. , Stagliano N. , Fairchild-Huntress V. , Xu J. , Lorenz J.N. , Kadambi V. , Berul C.I. , Breitbart R.E.
J. Mol. Cell. Cardiol.35:1043-1053(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
5.

"Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2."
Li W. , Greenough T.C. , Moore M.J. , Vasilieva N. , Somasundaran M. , Sullivan J.L. , Farzan M. , Choe H.
J. Virol.78:11429-11433(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SARS-COV S PROTEIN
6.

"Angiotensin-converting enzyme 2 protects from severe acute lung failure."
Imai Y. , Kuba K. , Rao S. , Huan Y. , Guo F. , Guan B. , Yang P. , Sarao R. , Wada T. , Leong-Poi H. , Crackower M.A. , Fukamizu A. , Hui C.-C. , Hein L. , Uhlig S. , Slutsky A.S. , Jiang C. , Penninger J.M.
Nature436:112-116(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION;FUNCTION
7.

"Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents."
Gembardt F. , Sterner-Kock A. , Imboden H. , Spalteholz M. , Reibitz F. , Schultheiss H.-P. , Siems W.-E. , Walther T.
Peptides26:1270-1277(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"Angiotensin II regulates ACE and ACE2 in neurons through p38 mitogen-activated protein kinase and extracellular signal-regulated kinase 1/2 signaling."
Xiao L. , Haack K.K. , Zucker I.H.
Am. J. Physiol.304:C1073-C1079(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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