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Index > Protein center > CHRNA7(Gene name) > Chicken
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  • CHRNA7 (Gene name),
  • Neuronal acetylcholine receptor subunit alpha-7 (Protein name ),  ACHA7_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CHRNA7;
    Protein name:
    Neuronal acetylcholine receptor subunit alpha-7;
    Alternative:

    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Forms a homo-oligomeric channel blocked by alpha-bungarotoxin. The structure is probably pentameric.
    Function:
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    502
    Sequence:
    50:
    MGLRALMLWL | LAAAGLVRES | LQGEFQRKLY | KELLKNYNPL | ERPVANDSQP | 
    100:
    LTVYFTLSLM | QIMDVDEKNQ | VLTTNIWLQM | YWTDHYLQWN | VSEYPGVKNV | 
    150:
    RFPDGLIWKP | DILLYNSADE | RFDATFHTNV | LVNSSGHCQY | LPPGIFKSSC | 
    200:
    YIDVRWFPFD | VQKCNLKFGS | WTYGGWSLDL | QMQEADISGY | ISNGEWDLVG | 
    250:
    IPGKRTESFY | ECCKEPYPDI | TFTVTMRRRT | LYYGLNLLIP | CVLISALALL | 
    300:
    VFLLPADSGE | KISLGITVLL | SLTVFMLLVA | EIMPATSDSV | PLIAQYFAST | 
    350:
    MIIVGLSVVV | TVIVLQYHHH | DPDGGKMPKW | TRVILLNWCA | WFLRMKRPGE | 
    400:
    DKVRPACQHK | QRRCSLSSME | MNTVSGQQCS | NGNMLYIGFR | GLDGVHCTPT | 
    450:
    TDSGVICGRM | TCSPTEEENL | LHSGHPSEGD | PDLAKILEEV | RYIANRFRDQ | 
    500:
    DEEEAICNEW | KFAASVVDRL | CLMAFSVFTI | ICTIGILMSA | PNFVEAVSKD | 
    502:
    FA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    E9618h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    E9618r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    E9618b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    E9618c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    E9618m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    U9618r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    U9618c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    U9618b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    U9618m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    U9618h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    P9618Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    P9618Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Cat.:
    P9618Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Polyclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Monoclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Monoclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Monoclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Monoclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Monoclonal Antibody for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Protein for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Protein for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Protein for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Protein for Chicken Neuronal acetylcholine receptor subunit alpha-7
    Protein for Chicken Neuronal acetylcholine receptor subunit alpha-7

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A neuronal nicotinic acetylcholine receptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX."
      Couturier S. , Bertrand D. , Matter J.-M. , Hernandez M.-C. , Bertrand S. , Millar N. , Valera S. , Barkas T. , Ballivet M.
      Neuron5:847-856(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Brain alpha-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily."
      Schoepfer R. , Conroy W.G. , Whiting P. , Gore M. , Lindstroem J.
      Neuron5:35-48(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "Neuronal specificity of the alpha 7 nicotinic acetylcholine receptor promoter develops during morphogenesis of the central nervous system."
      Matter-Sadzinski L. , Hernandez M.-C. , Roztocil T. , Ballivet M. , Matter J.-M.
      EMBO J.11:4529-4538(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-18
      strain: White leghorn.
      tissue: Erythrocyte.
    4. 4.
      "Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins."
      Conti-Tronconi B.M. , Dunn S.M.J. , Barnard E.A. , Dolly J.O. , Lai F.A. , Ray N. , Raftery M.A.
      Proc. Natl. Acad. Sci. U.S.A.82:5208-5212(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-47
      tissue: Brain.
    5. 5.
      "Mutations in the channel domain alter desensitization of a neuronal nicotinic receptor."
      Recah F. , Bertrand D. , Galzi J.-L. , Devillers-Thiery A. , Mulle C. , Hussy N. , Bertrand S. , Ballivet M. , Changeux J.-P.
      Nature353:846-849(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF LEU-270
    6. 6.
      "Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic."
      Galzi J.-L. , Devillers-Thiery A. , Hussy N. , Bertrand S. , Changeux J.-P. , Bertrand D.
      Nature359:500-505(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS TO CONVERT ION SELECTIVITY FROM CATIONIC TO ANIONIC
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