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Index > Protein center > Chrna1(Gene name) > Mouse
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  • Chrna1 (Gene name),
  • Acetylcholine receptor subunit alpha (Protein name ),  ACHA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Chrna1(Acra);
    Protein name:
    Acetylcholine receptor subunit alpha;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Pentamer of two alpha chains, and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) chains.
    Function:
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    457
    Sequence:
    50:
    MELSTVLLLL | GLCSAGLVLG | SEHETRLVAK | LFEDYSSVVR | PVEDHREIVQ | 
    100:
    VTVGLQLIQL | INVDEVNQIV | TTNVRLKQQW | VDYNLKWNPD | DYGGVKKIHI | 
    150:
    PSEKIWRPDV | VLYNNADGDF | AIVKFTKVLL | DYTGHITWTP | PAIFKSYCEI | 
    200:
    IVTHFPFDEQ | NCSMKLGTWT | YDGSVVAINP | ESDQPDLSNF | MESGEWVIKE | 
    250:
    ARGWKHWVFY | SCCPTTPYLD | ITYHFVMQRL | PLYFIVNVII | PCLLFSFLTS | 
    300:
    LVFYLPTDSG | EKMTLSISVL | LSLTVFLLVI | VELIPSTSSA | VPLIGKYMLF | 
    350:
    TMVFVIASII | ITVIVINTHH | RSPSTHIMPE | WVRKVFIDTI | PNIMFFSTMK | 
    400:
    RPSRDKQEKR | IFTEDIDISD | ISGKPGPPPM | GFHSPLIKHP | EVKSAIEGVK | 
    450:
    YIAETMKSDQ | ESNNAAEEWK | YVAMVMDHIL | LGVFMLVCLI | GTLAVFAGRL | 
    457:
    IELHQQG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Acetylcholine receptor subunit alpha
    ELISA Kit for Mouse Acetylcholine receptor subunit alpha
    ELISA Kit for Mouse Acetylcholine receptor subunit alpha
    ELISA Kit for Mouse Acetylcholine receptor subunit alpha
    ELISA Kit for Mouse Acetylcholine receptor subunit alpha
    CLIA Kit for Mouse Acetylcholine receptor subunit alpha
    CLIA Kit for Mouse Acetylcholine receptor subunit alpha
    CLIA Kit for Mouse Acetylcholine receptor subunit alpha
    CLIA Kit for Mouse Acetylcholine receptor subunit alpha
    CLIA Kit for Mouse Acetylcholine receptor subunit alpha
    Polyclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Polyclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Polyclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Polyclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Polyclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Monoclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Monoclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Monoclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Monoclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Monoclonal Antibody for Mouse Acetylcholine receptor subunit alpha
    Protein for Mouse Acetylcholine receptor subunit alpha
    Protein for Mouse Acetylcholine receptor subunit alpha
    Protein for Mouse Acetylcholine receptor subunit alpha
    Protein for Mouse Acetylcholine receptor subunit alpha
    Protein for Mouse Acetylcholine receptor subunit alpha

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Nucleotide sequence of the mouse muscle nicotinic acetylcholine receptor alpha subunit."
      Isenberg K.E. , Mudd J. , Shah V. , Merlie J.P.
      Nucleic Acids Res.14:5111-5111(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      Boulter J.
      Submitted (1997-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Head.
    4. 4.
      "Isolation of a clone coding for the alpha-subunit of a mouse acetylcholine receptor."
      Boulter J. , Luyten W. , Evans K. , Mason P. , Ballivet M. , Goldman D.J. , Stengelin S.F. , Martin G. , Heinemann S.F. , Patrick J.
      J. Neurosci.5:2545-2552(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 13-457
    5. 5.
      "Crystal structure of the extracellular domain of nAChR alpha1 bound to alpha-bungarotoxin at 1.94 A resolution."
      Dellisanti C.D. , Yao Y. , Stroud J.C. , Wang Z.Z. , Chen L.
      Nat. Neurosci.10:953-962(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.94 ANGSTROMS) OF 21-231 IN COMPLEX WITH ALPHA-BUNGAROTOXIN;DISULFIDE BONDS;GLYCOSYLATION AT ASN-161
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