Gene name:
Chrm3 (Chrm-3) ;
Protein name:
Muscarinic acetylcholine receptor M3 ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Cell junction
synapse
postsynaptic cell membrane
Multi-pass membrane protein
Basolateral cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MTLHSNSTTS | PLFPNISSSW | VHSPSEAGLP | LGTVTQLGSY | NISQETGNFS |
100:
SNDTSSDPLG | GHTIWQVVFI | AFLTGFLALV | TIIGNILVIV | AFKVNKQLKT |
150:
VNNYFLLSLA | CADLIIGVIS | MNLFTTYIIM | NRWALGNLAC | DLWLSIDYVA |
200:
SNASVMNLLV | ISFDRYFSIT | RPLTYRAKRT | TKRAGVMIGL | AWVISFVLWA |
250:
PAILFWQYFV | GKRTVPPGEC | FIQFLSEPTI | TFGTAIAAFY | MPVTIMTILY |
300:
WRIYKETEKR | TKELAGLQAS | GTEAEAENFV | HPTGSSRSCS | SYELQQQGVK |
350:
RSSRRKYGRC | HFWFTTKSWK | PSAEQMDQDH | SSSDSWNNND | AAASLENSAS |
400:
SDEEDIGSET | RAIYSIVLKL | PGHSSILNST | KLPSSDNLQV | SNEDLGTVDV |
450:
ERNAHKLQAQ | KSMGDGDNCQ | KDFTKLPIQL | ESAVDTGKTS | DTNSSADKTT |
500:
ATLPLSFKEA | TLAKRFALKT | RSQITKRKRM | SLIKEKKAAQ | TLSAILLAFI |
550:
ITWTPYNIMV | LVNTFCDSCI | PKTYWNLGYW | LCYINSTVNP | VCYALCNKTF |
589:
RTTFKTLLLC | QCDKRKRRKQ | QYQQRQSVIF | HKRVPEQAL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Chicken
Pig
Rat
ELISA Kit for Rat Muscarinic acetylcholine receptor M3
ELISA Kit for Rat Muscarinic acetylcholine receptor M3
ELISA Kit for Rat Muscarinic acetylcholine receptor M3
ELISA Kit for Rat Muscarinic acetylcholine receptor M3
ELISA Kit for Rat Muscarinic acetylcholine receptor M3
ELISA Kit for Rat Muscarinic acetylcholine receptor M3
CLIA Kit for Rat Muscarinic acetylcholine receptor M3
CLIA Kit for Rat Muscarinic acetylcholine receptor M3
CLIA Kit for Rat Muscarinic acetylcholine receptor M3
CLIA Kit for Rat Muscarinic acetylcholine receptor M3
CLIA Kit for Rat Muscarinic acetylcholine receptor M3
CLIA Kit for Rat Muscarinic acetylcholine receptor M3
Polyclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Polyclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Polyclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Polyclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Polyclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Polyclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Monoclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Monoclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Monoclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Monoclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Monoclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Monoclonal Antibody for Rat Muscarinic acetylcholine receptor M3
Protein for Rat Muscarinic acetylcholine receptor M3
Protein for Rat Muscarinic acetylcholine receptor M3
Protein for Rat Muscarinic acetylcholine receptor M3
Protein for Rat Muscarinic acetylcholine receptor M3
Protein for Rat Muscarinic acetylcholine receptor M3
Protein for Rat Muscarinic acetylcholine receptor M3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION TO 184
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Iris .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 104-166
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MUTAGENESIS OF TYR-148; THR-231; THR-234; TYR-506; TYR-529 AND TYR-533;FUNCTION;SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MUTAGENESIS OF THR-234 AND TYR-506;FUNCTION;SUBCELLULAR LOCATION
8.
"Structure and dynamics of the M3 muscarinic acetylcholine receptor."
Kruse A.C.
,
Hu J.
,
Pan A.C.
,
Arlow D.H.
,
Rosenbaum D.M.
,
Rosemond E.
,
Green H.F.
,
Liu T.
,
Chae P.S.
,
Dror R.O.
,
Shaw D.E.
,
Weis W.I.
,
Wess J.
,
Kobilka B.K.
Nature482:552-556(2012)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 57-589 IN COMPLEX WITH THE INVERSE AGONIST TIOTROPIUM;FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;DISULFIDE BOND