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Index > Protein center > ACO2(Gene name) > Human
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  • ACO2 (Gene name),
  • Aconitate hydratase, mitochondrial (Protein name ),  ACON_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ACO2;
    Protein name:
    Aconitate hydratase, mitochondrial(Aconitase);
    Alternative:
    Citrate hydro-lyase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    780
    Sequence:
    50:
    MAPYSLLVTR | LQKALGVRQY | HVASVLCQRA | KVAMSHFEPN | EYIHYDLLEK | 
    100:
    NINIVRKRLN | RPLTLSEKIV | YGHLDDPASQ | EIERGKSYLR | LRPDRVAMQD | 
    150:
    ATAQMAMLQF | ISSGLSKVAV | PSTIHCDHLI | EAQVGGEKDL | RRAKDINQEV | 
    200:
    YNFLATAGAK | YGVGFWKPGS | GIIHQIILEN | YAYPGVLLIG | TDSHTPNGGG | 
    250:
    LGGICIGVGG | ADAVDVMAGI | PWELKCPKVI | GVKLTGSLSG | WSSPKDVILK | 
    300:
    VAGILTVKGG | TGAIVEYHGP | GVDSISCTGM | ATICNMGAEI | GATTSVFPYN | 
    350:
    HRMKKYLSKT | GREDIANLAD | EFKDHLVPDP | GCHYDQLIEI | NLSELKPHIN | 
    400:
    GPFTPDLAHP | VAEVGKVAEK | EGWPLDIRVG | LIGSCTNSSY | EDMGRSAAVA | 
    450:
    KQALAHGLKC | KSQFTITPGS | EQIRATIERD | GYAQILRDLG | GIVLANACGP | 
    500:
    CIGQWDRKDI | KKGEKNTIVT | SYNRNFTGRN | DANPETHAFV | TSPEIVTALA | 
    550:
    IAGTLKFNPE | TDYLTGTDGK | KFRLEAPDAD | ELPKGEFDPG | QDTYQHPPKD | 
    600:
    SSGQHVDVSP | TSQRLQLLEP | FDKWDGKDLE | DLQILIKVKG | KCTTDHISAA | 
    650:
    GPWLKFRGHL | DNISNNLLIG | AINIENGKAN | SVRNAVTQEF | GPVPDTARYY | 
    700:
    KKHGIRWVVI | GDENYGEGSS | REHAALEPRH | LGGRAIITKS | FARIHETNLK | 
    750:
    KQGLLPLTFA | DPADYNKIHP | VDKLTIQGLK | DFTPGKPLKC | IIKHPNGTQE | 
    780:
    TILLNHTFNE | TQIEWFRAGS | ALNRMKELQQ | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    KEGG:
    Pfam:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Aconitase
    Cat.:
    E1263h
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    ELISA Kit for Human Aconitase
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    E1263m
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    ELISA Kit for Human Aconitase
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    E1263r
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    ELISA Kit for Human Aconitase
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    E1263p
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    ELISA Kit for Human Aconitase
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    E1263b
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    Packing:
    96T
    CLIA Kit for Human Aconitase
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    U1263b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Aconitase
    Cat.:
    U1263p
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Aconitase
    Cat.:
    U1263m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Aconitase
    Cat.:
    U1263h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Aconitase
    Cat.:
    U1263r
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Aconitase
    Polyclonal Antibody for Human Aconitase
    Cat.:
    P1263Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Aconitase
    Cat.:
    P1263Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Aconitase
    Cat.:
    P1263Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Aconitase
    Monoclonal Antibody for Human Aconitase
    Monoclonal Antibody for Human Aconitase
    Monoclonal Antibody for Human Aconitase
    Monoclonal Antibody for Human Aconitase
    Monoclonal Antibody for Human Aconitase
    Protein for Human Aconitase
    Protein for Human Aconitase
    Protein for Human Aconitase
    Protein for Human Aconitase
    Protein for Human Aconitase

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    References
    1. 1.
      "Cloning and structural characterization of human mitochondrial aconitase."
      Juang H.H. , Chiou B.
      Submitted (1996-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Skeletal muscle.
    2. 2.
      "Characterization of the human mitochondrial aconitase gene (ACO2)."
      Mirel D.B. , Marder K. , Graziano J. , Freyer G. , Zhao Q. , Mayeux R. , Wilhelmsen K.C.
      Gene213:205-218(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Uterus.
    7. 7.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 69-84; 234-245; 313-323; 379-395; 412-424; 430-437; 507-520; 565-573; 608-628; 634-648 AND 657-671;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    8. 8.
      "Purification and partial amino acid sequence of human aconitase."
      Baldwin G.S. , Seet K.L. , Callaghan J. , Toncich G. , Toh B.H. , Moritz R.L. , Rubira M.R. , Simpson R.
      Protein Seq. Data Anal.4:63-67(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 69-83; 96-107; 371-396 AND 524-534
    9. 9.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-573 AND LYS-605;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-559;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ASN-697
    13. 13.
      "Infantile cerebellar-retinal degeneration associated with a mutation in mitochondrial aconitase, ACO2."
      Spiegel R. , Pines O. , Ta-Shma A. , Burak E. , Shaag A. , Halvardson J. , Edvardson S. , Mahajna M. , Zenvirt S. , Saada A. , Shalev S. , Feuk L. , Elpeleg O.
      Am. J. Hum. Genet.90:518-523(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ICRD ARG-112;CHARACTERIZATION OF VARIANT ICRD ARG-112
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