Gene name:
ACOT8 (ACTEIII;PTE1;PTE2) ;
Protein name:
Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) ;
Alternative:
Choloyl-coenzyme A thioesterase ;Acyl-CoA thioesterase 8 ;PTE-2 (PTE-1) ;HIV-Nef-associated acyl-CoA thioesterase ;Peroxisomal long-chain acyl-CoA thioesterase 1 (hACTE-III) ;Peroxisomal acyl-coenzyme A thioester hydrolase 1 (PTE-1) ;Thioesterase II (hACTE-III;hACTEIII;hTE) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with HIV-1 Nef.
Function:
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.
Subcellular Location:
Peroxisome
Protein Attributes:
50:
MSSPQAPEDG | QGCGDRGDPP | GDLRSVLVTT | VLNLEPLDED | LFRGRHYWVP |
100:
AKRLFGGQIV | GQALVAAAKS | VSEDVHVHSL | HCYFVRAGDP | KLPVLYQVER |
150:
TRTGSSFSVR | SVKAVQHGKP | IFICQASFQQ | AQPSPMQHQF | SMPTVPPPEE |
200:
LLDCETLIDQ | YLRDPNLQKR | YPLALNRIAA | QEVPIEIKPV | NPSPLSQLQR |
250:
MEPKQMFWVR | ARGYIGEGDM | KMHCCVAAYI | SDYAFLGTAL | LPHQWQHKVH |
300:
FMVSLDHSMW | FHAPFRADHW | MLYECESPWA | GGSRGLVHGR | LWRQDGVLAV |
319:
TCAQEGVIRV | KPQVSESKL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Human Acyl-CoA thioesterase 8
ELISA Kit for Human Acyl-CoA thioesterase 8
ELISA Kit for Human Acyl-CoA thioesterase 8
CLIA Kit for Human Acyl-CoA thioesterase 8
CLIA Kit for Human Acyl-CoA thioesterase 8
CLIA Kit for Human Acyl-CoA thioesterase 8
Polyclonal Antibody for Human Acyl-CoA thioesterase 8
Polyclonal Antibody for Human Acyl-CoA thioesterase 8
Polyclonal Antibody for Human Acyl-CoA thioesterase 8
Monoclonal Antibody for Human Acyl-CoA thioesterase 8
Monoclonal Antibody for Human Acyl-CoA thioesterase 8
Monoclonal Antibody for Human Acyl-CoA thioesterase 8
Protein for Human Acyl-CoA thioesterase 8
Protein for Human Acyl-CoA thioesterase 8
Protein for Human Acyl-CoA thioesterase 8
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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