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Index > Protein center > Acot8(Gene name) > Rat
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  • Acot8 (Gene name),
  • Acyl-coenzyme A thioesterase 8 (Protein name ),  ACOT8_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Acot8(Pte1;Pte2);
    Protein name:
    Acyl-coenzyme A thioesterase 8(Acyl-CoA thioesterase 8);
    Alternative:
    Choloyl-coenzyme A thioesterase(PTE-2);Acyl-CoA thioesterase 8;Peroxisomal acyl-coenzyme A thioester hydrolase 1(PTE-1);Peroxisomal acyl-CoA thioesterase 2(PTE-2);Peroxisomal long-chain acyl-CoA thioesterase 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA (chenodeoxycholoyl-CoA) substrate. Shows a preference for medium-length fatty acyl-CoAs. May be involved in the metabolic regulation of peroxisome proliferation.
    Subcellular Location:
    Peroxisome
    Protein Attributes:
    Sequence length:
    320
    Sequence:
    50:
    MSKPEDLGDA | NGDADRGDLS | GDLRSVLVTS | VLNLEPLDED | LYRGRHYWVP | 
    100:
    TSQRLFGGQI | VGQALVAAAK | SVSEDVHVHS | LHCYFVRAGD | PKVPVLYHVE | 
    150:
    RTRTGASFSV | RAVKAVQHGK | AIFICQASFQ | QMQPSPLQHQ | FSMPTVPPPE | 
    200:
    ELLDHEALID | QYLRDPNLHE | KYRVGLNRIA | AREVPIEIKL | VNPPALNQLQ | 
    250:
    TLEPKQMFWV | RARGYIGEGD | IKMHCCVAAY | ISDYAFLGTA | LLPHQSKYKV | 
    300:
    NFMVSLDHSM | WFHAPFRADH | WMLYECESPW | AGGSRGLVHG | RLWRRDGVLA | 
    320:
    VTCAQEGVIR | SKPRVSESKL | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Acyl-CoA thioesterase 8
    ELISA Kit for Rat Acyl-CoA thioesterase 8
    ELISA Kit for Rat Acyl-CoA thioesterase 8
    CLIA Kit for Rat Acyl-CoA thioesterase 8
    CLIA Kit for Rat Acyl-CoA thioesterase 8
    CLIA Kit for Rat Acyl-CoA thioesterase 8
    Polyclonal Antibody for Rat Acyl-CoA thioesterase 8
    Polyclonal Antibody for Rat Acyl-CoA thioesterase 8
    Polyclonal Antibody for Rat Acyl-CoA thioesterase 8
    Monoclonal Antibody for Rat Acyl-CoA thioesterase 8
    Monoclonal Antibody for Rat Acyl-CoA thioesterase 8
    Monoclonal Antibody for Rat Acyl-CoA thioesterase 8
    Protein for Rat Acyl-CoA thioesterase 8
    Protein for Rat Acyl-CoA thioesterase 8
    Protein for Rat Acyl-CoA thioesterase 8

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    Precision
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    Linearity
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    References
    1. 1.
      "Demonstration of dimethylnonanoyl-CoA thioesterase activity in rat liver peroxisomes followed by purification and molecular cloning of the thioesterase involved."
      Ofman R. , el Mrabet L. , Dacremont G. , Spijer D. , Wanders R.J.
      Biochem. Biophys. Res. Commun.290:629-634(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INDUCTION
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