APEH ELISA Kit for Human(Homo sapiens) | EIAab.comAPEH ELISA Kit for Human(Homo sapiens)

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Index > Protein center > APEH(Gene name) > Human

APEH (Gene name),

Acylamino-acid-releasing enzyme (Protein name ), ACPH_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

APEH(D3F15S2;D3S48E;DNF15S2);

Protein name:

Acylamino-acid-releasing enzyme(AARE);

Alternative:

Acylaminoacyl-peptidase;Acyl-peptide hydrolase(APH);Oxidized protein hydrolase(OPH);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homotetramer.

Function:

This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

732

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

732:

LYPKSTHALS | EVEVESDSFM | NAVLWLRTHL | GS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000296456

KEGG:

hsa:327

Pfam:

PF00326

UniGene:

Hs.517969

String:

P13798

SMR:

P13798

MIM:

102645

Uniprot:

P13798

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ELISA Kit for Human AARE

Cat.:

E14162h

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Manual:

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Packing:

96T

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ELISA Kit for Human AARE

MSDS:

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ELISA Kit for Human AARE

MSDS:

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ELISA Kit for Human AARE

MSDS:

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ELISA Kit for Human AARE

Cat.:

E14162m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Human AARE

MSDS:

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CLIA Kit for Human AARE

MSDS:

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CLIA Kit for Human AARE

MSDS:

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CLIA Kit for Human AARE

MSDS:

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CLIA Kit for Human AARE

MSDS:

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CLIA Kit for Human AARE

Cat.:

U14162h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human AARE

Cat.:

U14162m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Human AARE

Monoclonal Antibody for Human AARE

Protein for Human AARE

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The nucleotide sequence of human acylamino acid-releasing enzyme."
Mitta M. , Ohnogi H. , Mizutani S. , Sakiyama F. , Kato I. , Tsunasawa S.
DNA Res.3:31-35(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
2.

"Identification of oxidized protein hydrolase of human erythrocytes as acylpeptide hydrolase."
Fujino T. , Watanabe K. , Beppu M. , Kikugawa K. , Yasuda H.
Biochim. Biophys. Acta1478:102-112(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Muscle.
4.

"The DNF15S2 locus at 3p21 is transcribed in normal lung and small cell lung cancer."
Naylor S.L. , Marshall A. , Hensel C. , Martinez P.F. , Holley B. , Sakaguchi A.Y.
Genomics4:355-361(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY NUCLEOTIDE SEQUENCE OF 102-732
5.

"Structural investigations on human erythrocyte acylpeptide hydrolase by mass spectrometric procedures."
Scaloni A. , Ingallinella P. , Andolfo A. , Jones W. , Marino G. , Manning J.M.
J. Protein Chem.18:349-360(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;MASS SPECTROMETRY;ACETYLATION AT MET-1
6.

"The gene from the short arm of chromosome 3, at D3F15S2, frequently deleted in renal cell carcinoma, encodes acylpeptide hydrolase."
Erlandsson R. , Boldog F. , Persson B. , Zabarovsky E.R. , Allikmets R.L. , Sumegi J. , Klein G. , Joernvall H.
Oncogene6:1293-1295(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"Genetic relationship between acylpeptide hydrolase and acylase, two hydrolytic enzymes with similar binding but different catalytic specificities."
Jones W.M. , Scaloni A. , Bossa F. , Popowicz A.M. , Schneewind O. , Manning J.M.
Proc. Natl. Acad. Sci. U.S.A.88:2194-2198(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"Acylpeptide hydrolase: inhibitors and some active site residues of the human enzyme."
Scaloni A. , Jones W.M. , Barra D. , Pospischil M. , Sassa S. , Popowicz A. , Manning L.R. , Schneewind O. , Manning J.M.
J. Biol. Chem.267:3811-3818(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACTIVE SITES SER-587 AND HIS-707
9.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
10.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-185 AND SER-187;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
11.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-187;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Crystallization and preliminary X-ray studies of human erythrocyte acylpeptide hydrolase."
Feese M. , Scaloni A. , Jones W.M. , Mannig J.M. , Remington S.J.
J. Mol. Biol.233:546-549(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)

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