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Index > Protein center > ACR(Gene name) > Human
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  • ACR (Gene name),
  • Acrosin (Protein name ),  ACRO_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ACR(ACRS);
    Protein name:
    Acrosin;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heavy chain (catalytic) and a light chain linked by two disulfide bonds.
    Function:
    Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome.
    Subcellular Location:
    Protein Attributes:
    Sequence length:
    421
    Sequence:
    50:
    MVEMLPTAIL | LVLAVSVVAK | DNATCDGPCG | LRFRQNPQGG | VRIVGGKAAQ | 
    100:
    HGAWPWMVSL | QIFTYNSHRY | HTCGGSLLNS | RWVLTAAHCF | VGKNNVHDWR | 
    150:
    LVFGAKEITY | GNNKPVKAPL | QERYVEKIII | HEKYNSATEG | NDIALVEITP | 
    200:
    PISCGRFIGP | GCLPHFKAGL | PRGSQSCWVA | GWGYIEEKAP | RPSSILMEAR | 
    250:
    VDLIDLDLCN | STQWYNGRVQ | PTNVCAGYPV | GKIDTCQGDS | GGPLMCKDSK | 
    300:
    ESAYVVVGIT | SWGVGCARAK | RPGIYTATWP | YLNWIASKIG | SNALRMIQSA | 
    350:
    TPPPPTTRPP | PIRPPFSHPI | SAHLPWYFQP | PPRPLPPRPP | AAQPRPPPSP | 
    400:
    PPPPPPPASP | LPPPPPPPPP | TPSSTTKLPQ | GLSFAKRLQQ | LIEVLKGKTY | 
    421:
    SDGKNHYDME | TTELPELTST | S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    MIM:
    Pfam:
    String:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Acrosin
    Cat.:
    E1947h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Acrosin
    MSDS:
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    ELISA Kit for Human Acrosin
    Cat.:
    E1947r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Acrosin
    Cat.:
    E1947p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Acrosin
    Cat.:
    E1947m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Acrosin
    Cat.:
    U1947p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Acrosin
    Cat.:
    U1947m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Acrosin
    Cat.:
    U1947r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Acrosin
    Cat.:
    U1947h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Acrosin
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human Acrosin
    Cat.:
    P1947Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Acrosin
    Cat.:
    P1947Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Acrosin
    Polyclonal Antibody for Human Acrosin
    Polyclonal Antibody for Human Acrosin
    Cat.:
    P1947Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Acrosin
    Monoclonal Antibody for Human Acrosin
    Monoclonal Antibody for Human Acrosin
    Monoclonal Antibody for Human Acrosin
    Monoclonal Antibody for Human Acrosin
    Protein for Human Acrosin
    Protein for Human Acrosin
    Protein for Human Acrosin
    Protein for Human Acrosin
    Protein for Human Acrosin

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    References
    1. 1.
      "Primary structure of human proacrosin deduced from its cDNA sequence."
      Baba T. , Watanabe K. , Kashiwabara S. , Arai Y.
      FEBS Lett.244:296-300(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
    2. 2.
      "Nucleotide sequence and exon-intron organization of the human proacrosin gene."
      Keime S. , Adham I.M. , Engel W.
      Eur. J. Biochem.190:195-200(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Leukocyte.
    3. 3.
      "Molecular cloning of human preproacrosin cDNA."
      Adham I.M. , Klemm U. , Maier W.-M. , Engel W.
      Hum. Genet.84:125-128(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      "Molecular cloning, sequencing and restriction mapping of the genomic sequence encoding human proacrosin."
      Vazquez-Levin M.H. , Reventos J. , Gordon J.W.
      Eur. J. Biochem.207:23-26(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;DISCUSSION OF PUBMED:1628652
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa."
      Zheng X. , Geiger M. , Ecke S. , Bielek E. , Donner P. , Eberspacher U. , Schleuning W.D. , Binder B.R.
      Am. J. Physiol.267:C466-C472(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;HETERODIMER WITH SERPINA5
    8. 8.
      "Evaluation of the proacrosin/acrosin system and its mechanism of activation in human sperm extracts."
      Zahn A. , Furlong L.I. , Biancotti J.C. , Ghiringhelli P.D. , Marijn-Briggiler C.I. , Vazquez-Levin M.H.
      J. Reprod. Immunol.54:43-63(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROPEPTIDE;ACTIVATION
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