Protein name:
Alpha-actinin-4 ;
Alternative:
Non-muscle alpha-actinin 4 ;F-actin cross-linking protein ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homodimer; antiparallel. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Binds TRIM3 at the N-terminus. Interacts with BAIAP1 and PDLIM2 (By similarity). Identified in a complex with CASK, IQGAP1, MAGI2, NPHS1, SPTAN1 and SPTBN1.
Function:
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
Subcellular Location:
Nucleus
Cytoplasm
Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers.
Protein Attributes:
50:
MVDYHAANQS | YQYGPSSGSN | GAGGGGTMGD | YMAQEDDWDR | DLLLDPAWEK |
100:
QQRKTFTAWC | NSHLRKAGTQ | IENIDEDFRD | GLKLMLLLEV | ISGERLPKPE |
150:
RGKMRVHKIN | NVNKALDFIA | SKGVKLVSIG | AEEIVDGNAK | MTLGMIWTII |
200:
LRFAIQDISV | EETSAKEGLL | LWCQRKTAPY | KNVNVQNFHI | SWKDGLAFNA |
250:
LIHRHRPELI | EYDKLRKDDP | VTNLNNAFEV | AEKYLDIPKM | LDAEDIVNTA |
300:
RPDEKAIMTY | VSSFYHAFSG | AQKAETAANR | ICKVLAVNQE | NEHLMEDYER |
350:
LASDLLEWIR | RTIPWLEDRV | PQKTIQEMQQ | KLEDFRDYRR | VHKPPKVQEK |
400:
CQLEINFNTL | QTKLRLSNRP | AFMPSEGKMV | SDINNGWQHL | EQAEKGYEEW |
450:
LLNEIRRLER | LDHLAEKFRQ | KASIHEAWTD | GKEAMLKHRD | YETATLSDIK |
500:
ALIRKHEAFE | SDLAAHQDRV | EQIAAIAQEL | NELDYYDSHN | VNTRCQKICD |
550:
QWDALGSLTH | SRREALEKTE | KQLETIDQLH | LEYAKRAAPF | NNWMESAMED |
600:
LQDMFIVHTI | EEIEGLISAH | DQFKSTLPDA | DREREAILAI | HKEAQRIAES |
650:
NHIKLSGSNP | YTTVTPQIIN | SKWEKVQQLV | PKRDHALLEE | QSKQQSNEHL |
700:
RRQFASQANI | VGPWIQTKME | EIGRISIEMN | GTLEDQLSHL | KQYERSIVDY |
750:
KPNLDLLEQQ | HQLIQEALIF | DNKHTNYTME | HIRVGWEQLL | TTIARTINEV |
800:
ENQILTRDAK | GISQEQMQEF | RASFNHFDKD | HGGALGPEEF | KACLISLGYD |
850:
VENDRQGDAE | FNRIMSVVDP | NHSGLVTFQA | FIDFMSRETT | DTDTADQVIA |
900:
SFKVLAGDKN | FITAEELRRE | LPPDQAEYCI | ARMAPYQGPD | AVPGALDYKS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Rat
Mouse
Bovine
ELISA Kit for Bovine Alpha-actinin-4
ELISA Kit for Bovine Alpha-actinin-4
ELISA Kit for Bovine Alpha-actinin-4
ELISA Kit for Bovine Alpha-actinin-4
ELISA Kit for Bovine Alpha-actinin-4
CLIA Kit for Bovine Alpha-actinin-4
CLIA Kit for Bovine Alpha-actinin-4
CLIA Kit for Bovine Alpha-actinin-4
CLIA Kit for Bovine Alpha-actinin-4
CLIA Kit for Bovine Alpha-actinin-4
Polyclonal Antibody for Bovine Alpha-actinin-4
Polyclonal Antibody for Bovine Alpha-actinin-4
Polyclonal Antibody for Bovine Alpha-actinin-4
Polyclonal Antibody for Bovine Alpha-actinin-4
Polyclonal Antibody for Bovine Alpha-actinin-4
Monoclonal Antibody for Bovine Alpha-actinin-4
Monoclonal Antibody for Bovine Alpha-actinin-4
Monoclonal Antibody for Bovine Alpha-actinin-4
Monoclonal Antibody for Bovine Alpha-actinin-4
Monoclonal Antibody for Bovine Alpha-actinin-4
Protein for Bovine Alpha-actinin-4
Protein for Bovine Alpha-actinin-4
Protein for Bovine Alpha-actinin-4
Protein for Bovine Alpha-actinin-4
Protein for Bovine Alpha-actinin-4
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Ascending colon .