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Index > Protein center > ACTN4(Gene name) > Bovine
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  • ACTN4 (Gene name),
  • Alpha-actinin-4 (Protein name ),  ACTN4_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ACTN4;
    Protein name:
    Alpha-actinin-4;
    Alternative:
    Non-muscle alpha-actinin 4;F-actin cross-linking protein;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer; antiparallel. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Binds TRIM3 at the N-terminus. Interacts with BAIAP1 and PDLIM2 (By similarity). Identified in a complex with CASK, IQGAP1, MAGI2, NPHS1, SPTAN1 and SPTBN1.
    Function:
    F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.
    Subcellular Location:
    Nucleus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers.
    Protein Attributes:
    Sequence length:
    911
    Sequence:
    50:
    MVDYHAANQS | YQYGPSSGSN | GAGGGGTMGD | YMAQEDDWDR | DLLLDPAWEK | 
    100:
    QQRKTFTAWC | NSHLRKAGTQ | IENIDEDFRD | GLKLMLLLEV | ISGERLPKPE | 
    150:
    RGKMRVHKIN | NVNKALDFIA | SKGVKLVSIG | AEEIVDGNAK | MTLGMIWTII | 
    200:
    LRFAIQDISV | EETSAKEGLL | LWCQRKTAPY | KNVNVQNFHI | SWKDGLAFNA | 
    250:
    LIHRHRPELI | EYDKLRKDDP | VTNLNNAFEV | AEKYLDIPKM | LDAEDIVNTA | 
    300:
    RPDEKAIMTY | VSSFYHAFSG | AQKAETAANR | ICKVLAVNQE | NEHLMEDYER | 
    350:
    LASDLLEWIR | RTIPWLEDRV | PQKTIQEMQQ | KLEDFRDYRR | VHKPPKVQEK | 
    400:
    CQLEINFNTL | QTKLRLSNRP | AFMPSEGKMV | SDINNGWQHL | EQAEKGYEEW | 
    450:
    LLNEIRRLER | LDHLAEKFRQ | KASIHEAWTD | GKEAMLKHRD | YETATLSDIK | 
    500:
    ALIRKHEAFE | SDLAAHQDRV | EQIAAIAQEL | NELDYYDSHN | VNTRCQKICD | 
    550:
    QWDALGSLTH | SRREALEKTE | KQLETIDQLH | LEYAKRAAPF | NNWMESAMED | 
    600:
    LQDMFIVHTI | EEIEGLISAH | DQFKSTLPDA | DREREAILAI | HKEAQRIAES | 
    650:
    NHIKLSGSNP | YTTVTPQIIN | SKWEKVQQLV | PKRDHALLEE | QSKQQSNEHL | 
    700:
    RRQFASQANI | VGPWIQTKME | EIGRISIEMN | GTLEDQLSHL | KQYERSIVDY | 
    750:
    KPNLDLLEQQ | HQLIQEALIF | DNKHTNYTME | HIRVGWEQLL | TTIARTINEV | 
    800:
    ENQILTRDAK | GISQEQMQEF | RASFNHFDKD | HGGALGPEEF | KACLISLGYD | 
    850:
    VENDRQGDAE | FNRIMSVVDP | NHSGLVTFQA | FIDFMSRETT | DTDTADQVIA | 
    900:
    SFKVLAGDKN | FITAEELRRE | LPPDQAEYCI | ARMAPYQGPD | AVPGALDYKS | 
    911:
    FSTALYGESD | L
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Alpha-actinin-4
    Cat.:
    E1460h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Bovine Alpha-actinin-4
    Cat.:
    E1460c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Alpha-actinin-4
    Cat.:
    E1460r
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    Packing:
    96T
    ELISA Kit for Bovine Alpha-actinin-4
    Cat.:
    E1460m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Alpha-actinin-4
    Cat.:
    E1460b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Alpha-actinin-4
    Cat.:
    U1460m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Alpha-actinin-4
    Cat.:
    U1460h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Alpha-actinin-4
    Cat.:
    U1460r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Alpha-actinin-4
    Cat.:
    U1460c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Alpha-actinin-4
    Cat.:
    U1460b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Alpha-actinin-4
    Polyclonal Antibody for Bovine Alpha-actinin-4
    Cat.:
    P1460Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Alpha-actinin-4
    Polyclonal Antibody for Bovine Alpha-actinin-4
    Cat.:
    P1460Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Alpha-actinin-4
    Cat.:
    P1460Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Alpha-actinin-4
    Monoclonal Antibody for Bovine Alpha-actinin-4
    Monoclonal Antibody for Bovine Alpha-actinin-4
    Monoclonal Antibody for Bovine Alpha-actinin-4
    Monoclonal Antibody for Bovine Alpha-actinin-4
    Protein for Bovine Alpha-actinin-4
    Protein for Bovine Alpha-actinin-4
    Protein for Bovine Alpha-actinin-4
    Protein for Bovine Alpha-actinin-4
    Protein for Bovine Alpha-actinin-4

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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Ascending colon.
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