Actn4 ELISA Kit for Mouse(Mus musculus) | EIAab.comActn4 ELISA Kit for Mouse(Mus musculus)

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Actn4 (Gene name),

Alpha-actinin-4 (Protein name ), ACTN4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Actn4;

Protein name:

Alpha-actinin-4;

Alternative:

Non-muscle alpha-actinin 4;F-actin cross-linking protein;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer; antiparallel (By similarity). Interacts with BAIAP1 and PDLIM2 (By similarity). Identified in a complex with CASK, IQGAP1, MAGI2, NPHS1, SPTAN1 and SPTBN1 (By similarity). Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Binds TRIM3 at the N-terminus.

Function:

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Subcellular Location:

Nucleus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers.

Protein Attributes:

Sequence length:

912

Sequence:

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912:

SFSTALYGES | DL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:60595

Pfam:

PF00307

String:

P57780

UniGene:

Mm.81144

SMR:

P57780

Uniprot:

P57780

FOR

ELISA Kit for Mouse Alpha-actinin-4

Cat.:

E1460h

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Manual:

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96T

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ELISA Kit for Mouse Alpha-actinin-4

Cat.:

E1460c

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96T

ELISA Kit for Mouse Alpha-actinin-4

Cat.:

E1460r

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96T

ELISA Kit for Mouse Alpha-actinin-4

Cat.:

E1460m

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96T

ELISA Kit for Mouse Alpha-actinin-4

Cat.:

E1460b

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96T

CLIA Kit for Mouse Alpha-actinin-4

Cat.:

U1460m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Alpha-actinin-4

Cat.:

U1460h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Alpha-actinin-4

Cat.:

U1460r

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Packing:

96T

CLIA Kit for Mouse Alpha-actinin-4

Cat.:

U1460c

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Alpha-actinin-4

Cat.:

U1460b

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Packing:

96T

Polyclonal Antibody for Mouse Alpha-actinin-4

Cat.:

P1460Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Alpha-actinin-4

Cat.:

P1460Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Alpha-actinin-4

Cat.:

P1460Rb-m

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40ug/0.2ml

Monoclonal Antibody for Mouse Alpha-actinin-4

Protein for Mouse Alpha-actinin-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Gene structure, chromosomal localization and expression pattern of Capn12, a new member of the calpain large subunit gene family."
Dear T.N. , Meier N.T. , Hunn M. , Boehm T.
Genomics68:152-160(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: 129.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Mammary gland.
3.

Lubec G. , Kang S.U.
Submitted (2007-04) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 85-96 AND 311-319;IDENTIFICATION BY MASS SPECTROMETRY
strain: C57BL/6.
tissue: Brain.
4.

"Involvement of actinin-4 in the recruitment of JRAB/MICAL-L2 to cell-cell junctions and the formation of functional tight junctions."
Nakatsuji H. , Nishimura N. , Yamamura R. , Kanayama H.O. , Sasaki T.
Mol. Cell. Biol.28:3324-3335(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TIGHT JUNCTION ASSEMBLY;INTERACTION WITH MICALL2;SUBCELLULAR LOCATION
5.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-780 AND LYS-860;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.

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