Gene name:
Acvrl1 (Acvrlk1;Alk-1) ;
Protein name:
Serine/threonine-protein kinase receptor R3 (SKR3) ;
Alternative:
TGF-B superfamily receptor type I (TSR-I) ;Activin receptor-like kinase 1 (ALK-1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MTLGSFRRGL | LMLSVAFGLT | RGDLAKPSKL | VNCTCESPHC | KRPFCQGSWC |
100:
TVVLVREQGR | HPQVYRGCGS | LNQELCLGRP | TEFLNHHCCY | RSFCNHNVSL |
150:
MLEATQTPSE | EPEVDAHLPL | ILGPVLALPV | LVALGALGLW | RVRRRQEKQR |
200:
DLHSDLGESS | LILKASEQAD | SMLGDFLDSD | CTTGSGSGLP | FLVQRTVARQ |
250:
VALVECVGKG | RYGEVWRGSW | HGESVAVKIF | SSRDEQSWFR | ETEIYNTVLL |
300:
RHDNILGFIA | SDMTSRNSST | QLWLITHYHE | HGSLYDFLQR | QTLEPQLALR |
350:
LAVSAACGLA | HLHVEIFGTQ | GKPAIAHRDL | KSRNVLVKSN | LQCCIADLGL |
400:
AVMHSQSSDY | LDIGNNPRVG | TKRYMAPEVL | DEHIRTDCFE | SYKWTDIWAF |
450:
GLVLWEIARR | TIINGIVEDY | RPPFYDMVPN | DPSFEDMKKV | VCVDQQTPTI |
500:
PNRLAADPVL | SGLAQMMREC | WYPNPSARLT | ALRIKKTLQK | LSHNPEKPKV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Polyclonal Antibody for Mouse SKR3
Polyclonal Antibody for Mouse SKR3
Polyclonal Antibody for Mouse SKR3
Monoclonal Antibody for Mouse SKR3
Monoclonal Antibody for Mouse SKR3
Monoclonal Antibody for Mouse SKR3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Placenta .
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"The transcriptional landscape of the mammalian genome."
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary tumor .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-154;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]