Gene name:
ADAM9 (KIAA0021;MCMP;MDC9;MLTNG) ;
Protein name:
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM 9) ;
Alternative:
Meltrin-gamma ;Cellular disintegrin-related protein ;Myeloma cell metalloproteinase ;Metalloprotease/disintegrin/cysteine-rich protein 9 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Probable zinc protease. May mediate cell-cell or cell-matrix interactions. Isoform 2 displays alpha-secretase activity for APP.
Subcellular Location:
Isoform 2
Secreted
Protein Attributes:
50:
MGSGARFPSG | TLRVRWLLLL | GLVGPVLGAA | RPGFQQTSHL | SSYEIITPWR |
100:
LTRERREAPR | PYSKQVSYVI | QAEGKEHIIH | LERNKDLLPE | DFVVYTYNKE |
150:
GTLITDHPNI | QNHCHYRGYV | EGVHNSSIAL | SDCFGLRGLL | HLENASYGIE |
200:
PLQNSSHFEH | IIYRMDDVYK | EPLKCGVSNK | DIEKETAKDE | EEEPPSMTQL |
250:
LRRRRAVLPQ | TRYVELFIVV | DKERYDMMGR | NQTAVREEMI | LLANYLDSMY |
300:
IMLNIRIVLV | GLEIWTNGNL | INIVGGAGDV | LGNFVQWREK | FLITRRRHDS |
350:
AQLVLKKGFG | GTAGMAFVGT | VCSRSHAGGI | NVFGQITVET | FASIVAHELG |
400:
HNLGMNHDDG | RDCSCGAKSC | IMNSGASGSR | NFSSCSAEDF | EKLTLNKGGN |
450:
CLLNIPKPDE | AYSAPSCGNK | LVDAGEECDC | GTPKECELDP | CCEGSTCKLK |
500:
SFAECAYGDC | CKDCRFLPGG | TLCRGKTSEC | DVPEYCNGSS | QFCQPDVFIQ |
550:
NGYPCQNNKA | YCYNGMCQYY | DAQCQVIFGS | KAKAAPKDCF | IEVNSKGDRF |
600:
GNCGFSGNEY | KKCATGNALC | GKLQCENVQE | IPVFGIVPAI | IQTPSRGTKC |
650:
WGVDFQLGSD | VPDPGMVNEG | TKCGAGKICR | NFQCVDASVL | NYDCDVQKKC |
700:
HGHGVCNSNK | NCHCENGWAP | PNCETKGYGG | SVDSGPTYNE | MNTALRDGLL |
750:
VFFFLIVPLI | VCAIFIFIKR | DQLWRSYFRK | KRSQTYESDG | KNQANPSRQP |
800:
GSVPRHVSPV | TPPREVPIYA | NRFAVPTYAA | KQPQQFPSRP | PPPQPKVSSQ |
819:
GNLIPARPAP | APPLYSSLT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human ADAM 9
ELISA Kit for Human ADAM 9
CLIA Kit for Human ADAM 9
CLIA Kit for Human ADAM 9
Polyclonal Antibody for Human ADAM 9
Polyclonal Antibody for Human ADAM 9
Monoclonal Antibody for Human ADAM 9
Monoclonal Antibody for Human ADAM 9
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Citations
[1].
K Kang, DG Song, EH Lee, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue :
Mammary carcinoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Placenta .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);TISSUE SPECIFICITY
tissue :
Bone marrow .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
6.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Lung .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SH3GL2 AND SNX9
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
11.
"Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice."
Parry D.A.
,
Toomes C.
,
Bida L.
,
Danciger M.
,
Towns K.V.
,
McKibbin M.
,
Jacobson S.G.
,
Logan C.V.
,
Ali M.
,
Bond J.
,
Chance R.
,
Swendeman S.
,
Daniele L.L.
,
Springell K.
,
Adams M.
,
Johnson C.A.
,
Booth A.P.
,
Jafri H.
,
Rashid Y.
,
Banin E.
,
Strom T.M.
,
Farber D.B.
,
Sharon D.
,
Blobel C.P.
,
Pugh E.N. Jr.
,
Pierce E.A.
,
Inglehearn C.F.
more...
Am. J. Hum. Genet.84:683-691(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INVOLVEMENT IN CORD9
12.
"Exploring the substrate affinities of MMP-3, ADAM-9 and ADAM-10 using molecular modelling and dynamics simulations."
Manzetti S.
,
McCulloch D.R.
,
Herington A.C.
Submitted (2002-06) to the PDB data bank
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : 3D-STRUCTURE MODELING OF 208-404