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Index > Protein center > Ada(Gene name) > Rat
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  • Ada (Gene name),
  • Adenosine deaminase (Protein name ),  ADA_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Ada;
    Protein name:
    Adenosine deaminase;
    Alternative:
    Adenosine aminohydrolase;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with DPP4 (extracellular domain).
    Function:
    Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Extracellular side Cell junction Cytoplasmic vesicle lumen Cytoplasm Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion.
    Protein Attributes:
    Sequence length:
    352
    Sequence:
    50:
    MAQTPAFNKP | KVELHVHLDG | AIKPETILYY | GKKRGIDLPA | DTVEGLRNII | 
    100:
    GMDKPLSLPD | FLAKFDYYMP | AIAGCREAIK | RIAYEFVEMK | AKEGVVYVEV | 
    150:
    RYSPHLLANS | KVDPIPWNQA | EGDLTPDEVV | DLVNQGLQEG | EQAFGIKVRS | 
    200:
    ILCCMRHQPS | WSPEVLELCK | KYHQKTVVAM | DLAGDETIEG | SSLFPGHVEA | 
    250:
    YEGAVKDGIH | RTVHAGEVGS | AEVVREAVDI | LKTERVGHGY | HTIEDEALYN | 
    300:
    RLLKENMHFE | VCPWSSYLTG | AWNPKTTHAV | VRFKDDQANY | SLNSDDPLIF | 
    350:
    KSTVDTDYQM | VKKDMGFTEE | EFKRLNINAA | KSSFLPEDEK | KELLERLYKE | 
    352:
    YQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Adenosine deaminase
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    E1390h
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    ELISA Kit for Rat Adenosine deaminase
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    E1390b
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    ELISA Kit for Rat Adenosine deaminase
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    E1390r
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    ELISA Kit for Rat Adenosine deaminase
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    E1390m
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    ELISA Kit for Rat Adenosine deaminase
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    E1390c
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    96T
    CLIA Kit for Rat Adenosine deaminase
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    U1390h
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    96T
    CLIA Kit for Rat Adenosine deaminase
    Cat.:
    U1390r
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    Packing:
    96T
    CLIA Kit for Rat Adenosine deaminase
    Cat.:
    U1390b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Adenosine deaminase
    Cat.:
    U1390m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Adenosine deaminase
    Cat.:
    U1390c
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    Packing:
    96T
    Polyclonal Antibody for Rat Adenosine deaminase
    Cat.:
    P1390Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Adenosine deaminase
    Cat.:
    P1390Rb-m
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    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Adenosine deaminase
    Polyclonal Antibody for Rat Adenosine deaminase
    Cat.:
    P1390Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Adenosine deaminase
    Monoclonal Antibody for Rat Adenosine deaminase
    Monoclonal Antibody for Rat Adenosine deaminase
    Monoclonal Antibody for Rat Adenosine deaminase
    Monoclonal Antibody for Rat Adenosine deaminase
    Monoclonal Antibody for Rat Adenosine deaminase
    Protein for Rat Adenosine deaminase
    Protein for Rat Adenosine deaminase
    Protein for Rat Adenosine deaminase
    Protein for Rat Adenosine deaminase
    Protein for Rat Adenosine deaminase

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    References
    1. 1.
      "Restricted expression of adenosine deaminase in rat leptomeninges and its role in the regulation of sleep."
      Okada T. , Mochizuki T. , Huag Z. , Sugita Y. , Urade Y. , Hayaishi O.
      Submitted (2001-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Leptomeninges.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Thymus.
    3. 3.
      "Adenosine deaminase in rodent median eminence: detection by antibody to the mouse enzyme and co-localization with adenosine deaminase-complexing protein (CD26)."
      Nagy J.I. , Yamamoto T. , Uemura H. , Schrader W.P.
      Neuroscience73:459-471(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    4. 4.
      "AMP deaminase and adenosine deaminase activities in liver and brain regions in acute ammonia intoxication and subacute toxic hepatitis."
      Kaminsky Y. , Kosenko E.
      Brain Res.1311:175-181(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
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