Protein name:
Adenylate cyclase type 10 ;
Alternative:
Adenylate cyclase homolog ;AH-related protein ;Testicular soluble adenylyl cyclase ;Germ cell soluble adenylyl cyclase (hsAC;sAC) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor. Involved in ciliary beat regulation.
Subcellular Location:
Cell membrane
Peripheral membrane protein
Cytoplasmic side
Cytoplasm
cytoskeleton
Cytoplasm
perinuclear region
Distributed to subcellular compartments containing cAMP targets. Found as a plasma membrane-associated protein, protein concentrated in the perinuclear region and protein colocalized with actin or tubulin.
Protein Attributes:
50:
MNTPKEEFQD | WPIVRIAAHL | PDLIVYGHFS | PERPFMDYFD | GVLMFVDISG |
100:
FTAMTEKFSS | AMYMDRGAEQ | LVEILNYHIS | AIVEKVLIFG | GDILKFAGDA |
150:
LLALWRVERK | QLKNIITVVI | KCSLEIHGLF | ETQEWEEGLD | IRVKIGLAAG |
200:
HISMLVFGDE | THSHFLVIGQ | AVDDVRLAQN | MAQMNDVILS | PNCWQLCDRS |
250:
MIEIESVPDQ | RAVKVNFLKP | PPNFNFDEFF | TKCTTFMHYY | PSGEHKNLLR |
300:
LACTLKPDPE | LEMSLQKYVM | ESILKQIDNK | QLQGYLSELR | PVTIVFVNLM |
350:
FEDQDKAEEI | GPAIQDAYMH | ITSVLKIFQG | QINKVFMFDK | GCSFLCVFGF |
400:
PGEKVPDELT | HALECAMDIF | DFCSQVHKIQ | TVSIGVASGI | VFCGIVGHTV |
450:
RHEYTVIGQK | VNLAARMMMY | YPGIVTCDSV | TYNGSNLPAY | FFKELPKKVM |
500:
KGVADSGPLY | QYWGRTEKVM | FGMACLICNR | KEDYPLLGRN | KEINYFMYTM |
550:
KKFLISNSSQ | VLMYEGLPGY | GKSQILMKIE | YLAQGKNHRI | IAISLNKISF |
600:
HQTFYTIQMF | MANVLGLDTC | KHYKERQTNL | RNKVMTLLDE | KFYCLLNDIF |
650:
HVQFPISREI | SRMSTLKKQK | QLEILFMKIL | KLIVKEERII | FIIDEAQFVD |
700:
STSWRFMEKL | IRTLPIFIIM | SLCPFVNIPC | AAARAVIKNR | NTTYIVIGAV |
750:
QPNDISNKIC | LDLNVSCISK | ELDSYLGEGS | CGIPFYCEEL | LKNLEHHEVL |
800:
VFQQTESEEK | TNRTWNNLFK | YSIKLTEKLN | MVTLHSDKES | EEVCHLTSGV |
850:
RLKNLSPPTS | LKEISLIQLD | SMRLSHQMLV | RCAAIIGLTF | TTELLFEILP |
900:
CWNMKMMIKT | LATLVESNIF | YCFRNGKELQ | KALKQNDPSF | EVHYRSLSLK |
950:
PSEGMDHGEE | EQLRELENEV | IECHRIRFCN | PMMQKTAYEL | WLKDQRKAMH |
1000:
LKCARFLEED | AHRCDHCRGR | DFIPYHHFTV | NIRLNALDMD | AIKKMAMSHG |
1050:
FKTEEKLILS | NSEIPETSAF | FPENRSPEEI | REKILNFFDH | VLTKMKTSDE |
1100:
DIIPLESCQC | EEILEIVILP | LAHHFLALGE | NDKALYYFLE | IASAYLIFCD |
1150:
NYMAYMYLNE | GQKLLKTLKK | DKSWSQTFES | ATFYSLKGEV | CFNMGQIVLA |
1200:
KKMLRKALKL | LNRIFPYNLI | SLFLHIHVEK | NRHFHYVNRQ | AQESPPPGKK |
1250:
RLAQLYRQTV | CLSLLWRIYS | YSYLFHCKYY | AHLAVMMQMN | TALETQNCFQ |
1300:
IIKAYLDYSL | YHHLAGYKGV | WFKYEVMAME | HIFNLPLKGE | GIEIVAYVAE |
1350:
TLVFNKLIMG | HLDLAIELGS | RALQMWALLQ | NPNRHYQSLC | RLSRCLLLNS |
1400:
RYPQLIQVLG | RLWELSVTQE | HIFSKAFFYF | VCLDILLYSG | FVYRTFEECL |
1450:
EFIHQYENNR | ILKFHSGLLL | GLYSSVAIWY | ARLQEWDNFY | KFSNRAKNLL |
1500:
PRRTMTLTYY | DGISRYMEGQ | VLHLQKQIKE | QSENAQASGE | ELLKNLENLV |
1550:
AQNTTGPVFC | PRLYHLMAYV | CILMGDGQKC | GLFLNTALRL | SETQGNILEK |
1600:
CWLNMNKESW | YSTSELKEDQ | WLQTILSLPS | WEKIVAGRVN | IQDLQKNKFL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Rabbit
ELISA Kit for Human Adenylate cyclase type 10
ELISA Kit for Human Adenylate cyclase type 10
ELISA Kit for Human Adenylate cyclase type 10
ELISA Kit for Human Adenylate cyclase type 10
CLIA Kit for Human Adenylate cyclase type 10
CLIA Kit for Human Adenylate cyclase type 10
CLIA Kit for Human Adenylate cyclase type 10
CLIA Kit for Human Adenylate cyclase type 10
Polyclonal Antibody for Human Adenylate cyclase type 10
Polyclonal Antibody for Human Adenylate cyclase type 10
Polyclonal Antibody for Human Adenylate cyclase type 10
Polyclonal Antibody for Human Adenylate cyclase type 10
Monoclonal Antibody for Human Adenylate cyclase type 10
Monoclonal Antibody for Human Adenylate cyclase type 10
Monoclonal Antibody for Human Adenylate cyclase type 10
Monoclonal Antibody for Human Adenylate cyclase type 10
Protein for Human Adenylate cyclase type 10
Protein for Human Adenylate cyclase type 10
Protein for Human Adenylate cyclase type 10
Protein for Human Adenylate cyclase type 10
R&D Technical Data
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Precision
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Recovery
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Linearity
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,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;ENZYME REGULATION;SUBCELLULAR LOCATION;FUNCTION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY