Protein name:
Adenylate cyclase type 10 ;
Alternative:
Testicular soluble adenylyl cyclase ;Germ cell soluble adenylyl cyclase (sAC) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Soluble adenylyl cyclase that has a critical role in mammalian spermatogenesis. Produces the cAMP which mediates in part the cAMP-responsive nuclear factors indispensable for maturation of sperm in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization. May be the bicarbonate sensor.
Subcellular Location:
Cell membrane
Peripheral membrane protein
Cytoplasmic side
Cytoplasm
cytoskeleton
Mitochondrion
Cytoplasm
perinuclear region
Cytoplasm
cytoskeleton
centrosome
centriole
Distributed to subcellular compartments containing cAMP targets. Found as a plasma membrane-associated protein, protein concentrated in the perinuclear region and protein colocalized with actin, tubulin or centriole.
Protein Attributes:
50:
MSARRQELQD | RAIVKIAAHL | PDLIVYGDFS | PERPSVKCFD | GVLMFVDISG |
100:
FTAMTEKFST | AMYMDRGAEQ | LVEILNYYIS | AIVEKVLIFG | GDILKFAGDA |
150:
LLALWKVERK | QLKNIITVVI | KCSLEIHGLF | EAKEVEEGLD | IRVKIGLAAG |
200:
HITMLVFGDE | TRNYFLVIGQ | AVDDVRLAQN | MAQMNDVILS | PNCWQLCDRS |
250:
MIEIERIPDQ | RAVKVSFLKP | PPTFNFDEFF | AKCMAFMDYY | PSGDHKNFLR |
300:
LACMLESDPE | LELSLQKYVM | EIILKQIDDK | QLRGYLSELR | PVTIVFVNLM |
350:
FKEQDKAEVI | GSAIQAACVH | ITSVLKVFRG | QINKVFMFDK | GCSFLCVFGF |
400:
PGEKAPDEIT | HALESAVDIF | DFCSQVHKIR | TVSIGVASGI | VFCGIVGHTV |
450:
RHEYTVIGQK | VNIAARMMMY | YPGIVTCDSV | TYDGSNLPAY | FFKELPKKVM |
500:
KGVADPGPVY | QCLGLNEKVM | FGMAYLICNR | YEGYPLLGRV | REIDYFMSTM |
550:
KDFLMTNCSR | VLMYEGLPGY | GKSQVLMEIE | YLASQHENHR | AVAIALTKIS |
600:
FHQNFYTIQI | LMANVLGLDT | CKHYKERQTN | LQNRVKTLLD | DKYHCLLNDI |
650:
FHVQFPVSRE | MSRMSKIRKQ | KQLEALFMKI | LEQTVREERI | IFIIDEAQFV |
700:
DVASWAFIEK | LIRSMPIFIV | MSLCPFPETP | CAAANAIMKN | RNTTYITLGT |
750:
MQPQEIRDKV | CVDLSVSSIP | RELDSYLVEG | SCGIPYYCEE | LLKNLDHHRI |
800:
LIFQQAEAEE | KTNVTWNNLF | KYSVKPTEDM | YLYTSIAAGQ | KEACYLTSGV |
850:
RLKNLSPPAS | LKEISLVQLD | SMSLSHQMLV | RCAAIIGLTF | TTELLFEILP |
900:
CWNMKMMIKA | LATLVESNVF | DCFRSSKDLQ | LALKQNVTTF | EVHYRSLSLK |
950:
SKEGLAYSEE | EQLREMEGEV | IECRILRFCR | PIMQKTAYEL | WLKDQKKVLH |
1000:
LKCARFLEES | AHRCNHCRNR | DFIPYHHFIA | DIRLNTLDMD | TVKKMVKSHG |
1050:
FKTEDEVIFS | KSEIPRKFKF | PENISITETR | EKILHFFDNV | IIKMRTSQDD |
1100:
VIPLESCHCE | ELLQIVILPL | AQHFVALEEN | NKALYYFLEL | ASAYLILGDN |
1150:
YNAYMYLGEG | ERLLKSLTNE | DSWSQTFEYA | TFYSLKGEIC | FNMGQMVLAK |
1200:
KMLRKALKLL | NRMFPCNLLS | LTFQMHIEKN | RLSHFMNQHT | QEGSLPGKKL |
1250:
AQLFLQSSCF | SLLWKIYSLN | FFFHYKYYGR | LAAIMQMNTS | LETQNNFQII |
1300:
KAFLDFSLYR | HLAGYEGVWF | KYEILVMEQL | LNLPLKGEAF | EIMAYAADAL |
1350:
GHIKFLTGHL | DLAIELGSRA | HKMWSLLRNP | NKYHMVLCRL | SKPLFLKSRY |
1400:
KHLVQVLGWL | WDLSVTEEHI | FSKAFFYFVC | LDIMLYSGFI | YRTFEECLEF |
1450:
IHHNEDNRIL | KFQSGLLLGL | YSCIAVWYAR | LQEWDNFYKF | SNRAKTLVTR |
1500:
RTPTVLYYEG | ISRYMEGQVL | HLQKQIEEQA | ENAQDSGVEL | LKALETLVAQ |
1550:
NTTGPVFYPR | LYHLMAYVCI | LMGDGHSCDF | FLNTALELSE | TQGNLLEKCW |
1600:
LSMSKEWWYS | APELTGDQWL | QTVLSLPSWD | KIVSGNVTLQ | DVQKNKFLMR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
Rabbit
ELISA Kit for Rat Adenylate cyclase type 10
ELISA Kit for Rat Adenylate cyclase type 10
ELISA Kit for Rat Adenylate cyclase type 10
ELISA Kit for Rat Adenylate cyclase type 10
CLIA Kit for Rat Adenylate cyclase type 10
CLIA Kit for Rat Adenylate cyclase type 10
CLIA Kit for Rat Adenylate cyclase type 10
CLIA Kit for Rat Adenylate cyclase type 10
Polyclonal Antibody for Rat Adenylate cyclase type 10
Polyclonal Antibody for Rat Adenylate cyclase type 10
Polyclonal Antibody for Rat Adenylate cyclase type 10
Polyclonal Antibody for Rat Adenylate cyclase type 10
Monoclonal Antibody for Rat Adenylate cyclase type 10
Monoclonal Antibody for Rat Adenylate cyclase type 10
Monoclonal Antibody for Rat Adenylate cyclase type 10
Monoclonal Antibody for Rat Adenylate cyclase type 10
Protein for Rat Adenylate cyclase type 10
Protein for Rat Adenylate cyclase type 10
Protein for Rat Adenylate cyclase type 10
Protein for Rat Adenylate cyclase type 10
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 60-67; 254-262 AND 402-409;BIOPHYSICOCHEMICAL PROPERTIES;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
strain :
Sprague-Dawley .
tissue :
Testis .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ALTERNATIVE SPLICING
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : BIOPHYSICOCHEMICAL PROPERTIES