Aes ELISA Kit for Mouse(Mus musculus) | EIAab.comAes ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Aes(Gene name) > Mouse

Aes (Gene name),

Amino-terminal enhancer of split (Protein name ), AES_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Aes(Esp1;Grg);

Protein name:

Amino-terminal enhancer of split(Amino enhancer of split);

Alternative:

Protein ESP1;Grg-5;Protein GRG;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homooligomer and heterooligomer with other family members. Binds TCF7 and the NF-kappa-B subunit RELA. Interacts with PHF12.

Function:

Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

197

Sequence:

50:

100:

150:

197:

PPSLPAVSAG | TGLLSLSALG | SQTHLSKEDK | NGHDGDTHQE | DDGEKSD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P63002

Pfam:

PF03920

UniGene:

Mm.180013

KEGG:

mmu:14797

Uniprot:

P63002

FOR

ELISA Kit for Mouse Amino enhancer of split

CLIA Kit for Mouse Amino enhancer of split

Polyclonal Antibody for Mouse Amino enhancer of split

Monoclonal Antibody for Mouse Amino enhancer of split

Protein for Mouse Amino enhancer of split

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex."
Mallo M. , Franco del Amo F. , Gridley T.
Mech. Dev.42:67-76(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
2.

"Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein."
Miyasaka H. , Choudhury B.K. , Hou E.W. , Li S.S.-L.
Eur. J. Biochem.216:343-352(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
strain: CD-1.
3.

"The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors."
Roose J. , Molenaar M. , Peterson J. , Hurenkamp J. , Brantjes H. , Moerer P. , van de Wetering M. , Destree O. , Clevers H.
Nature395:608-612(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OLIGOMERIZATION;INTERACTION WITH TCF7
4.

"All Tcf HMG box transcription factors interact with Groucho-related co-repressors."
Brantjes H. , Roose J. , van De Wetering M. , Clevers H.
Nucleic Acids Res.29:1410-1419(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OLIGOMERIZATION;INTERACTION WITH TCF7
5.

"Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors."
Zhu C.C. , Dyer M.A. , Uchikawa M. , Kondoh H. , Lagutin O.V. , Oliver G.
Development129:2835-2849(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;INTERACTION WITH SIX3 AND SIX6

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