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Index > Protein center > AFM(Gene name) > Human
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  • AFM (Gene name),
  • Afamin (Protein name ),  AFAM_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AFM(ALB2;ALBA);
    Protein name:
    Afamin;
    Alternative:
    Alpha-albumin(Alpha-Alb);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    599
    Sequence:
    50:
    MKLLKLTGFI | FFLFFLTESL | TLPTQPRDIE | NFNSTQKFIE | DNIEYITIIA | 
    100:
    FAQYVQEATF | EEMEKLVKDM | VEYKDRCMAD | KTLPECSKLP | NNVLQEKICA | 
    150:
    MEGLPQKHNF | SHCCSKVDAQ | RRLCFFYNKK | SDVGFLPPFP | TLDPEEKCQA | 
    200:
    YESNRESLLN | HFLYEVARRN | PFVFAPTLLT | VAVHFEEVAK | SCCEEQNKVN | 
    250:
    CLQTRAIPVT | QYLKAFSSYQ | KHVCGALLKF | GTKVVHFIYI | AILSQKFPKI | 
    300:
    EFKELISLVE | DVSSNYDGCC | EGDVVQCIRD | TSKVMNHICS | KQDSISSKIK | 
    350:
    ECCEKKIPER | GQCIINSNKD | DRPKDLSLRE | GKFTDSENVC | QERDADPDTF | 
    400:
    FAKFTFEYSR | RHPDLSIPEL | LRIVQIYKDL | LRNCCNTENP | PGCYRYAEDK | 
    450:
    FNETTEKSLK | MVQQECKHFQ | NLGKDGLKYH | YLIRLTKIAP | QLSTEELVSL | 
    500:
    GEKMVTAFTT | CCTLSEEFAC | VDNLADLVFG | ELCGVNENRT | INPAVDHCCK | 
    550:
    TNFAFRRPCF | ESLKADKTYV | PPPFSQDLFT | FHADMCQSQN | EELQRKTDRF | 
    599:
    LVNLVKLKHE | LTDEELQSLF | TNFANVVDKC | CKAESPEVCF | NEESPKIGN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Afamin
    Cat.:
    E9608h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Afamin
    Cat.:
    E9608m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Afamin
    Cat.:
    E9608r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Afamin
    Cat.:
    U9608h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Afamin
    Cat.:
    U9608m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Afamin
    Cat.:
    U9608r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Afamin
    Cat.:
    P9608Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Afamin
    Cat.:
    P9608Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Afamin
    Monoclonal Antibody for Human Afamin
    Monoclonal Antibody for Human Afamin
    Monoclonal Antibody for Human Afamin
    Protein for Human Afamin
    Protein for Human Afamin
    Protein for Human Afamin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Afamin is a new member of the albumin, alpha-fetoprotein, and vitamin D-binding protein gene family."
      Lichenstein H.S. , Lyons D.E. , Wurfel M.M. , Johnson D.A. , McGinley M.D. , Leidli J.C. , Trollinger D.B. , Mayer J.P. , Wright S.D. , Zukowski M.M.
      J. Biol. Chem.269:18149-18154(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: Liver.
    2. 2.
      "Complete structure of the human alpha-albumin gene, a new member of the serum albumin multigene family."
      Nishio H. , Dugaiczyk A.
      Proc. Natl. Acad. Sci. U.S.A.93:7557-7561(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Heart.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "Identification of rat alpha-albumin and cDNA cloning of its human ortholog."
      Allard D. , Gilbert S. , Lamontagne A. , Hamel D. , Belanger L.
      Gene153:287-288(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-69; 105-207 AND 560-599
      tissue: Liver.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-45;GLYCOSYLATION;TISSUE SPECIFICITY;FUNCTION
    9. 9.
      "Characterization of the vitamin E-binding properties of human plasma afamin."
      Voegele A.F. , Jerkovic L. , Wellenzohn B. , Eller P. , Kronenberg F. , Liedl K.R. , Dieplinger H.
      Biochemistry41:14532-14538(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    10. 10.
      "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
      Bunkenborg J. , Pilch B.J. , Podtelejnikov A.V. , Wisniewski J.R.
      Proteomics4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-402
      tissue: Plasma.
    11. 11.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-33; ASN-402 AND ASN-488
      tissue: Plasma.
    12. 12.
      "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
      Ramachandran P. , Boontheung P. , Xie Y. , Sondej M. , Wong D.T. , Loo J.A.
      J. Proteome Res.5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-33
      tissue: Saliva.
    13. 13.
      "Afamin is synthesized by cerebrovascular endothelial cells and mediates alpha-tocopherol transport across an in vitro model of the blood-brain barrier."
      Kratzer I. , Bernhart E. , Wintersperger A. , Hammer A. , Waltl S. , Malle E. , Sperk G. , Wietzorrek G. , Dieplinger H. , Sattler W.
      J. Neurochem.108:707-718(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    14. 14.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-33 AND ASN-402
      tissue: Liver.
    15. 15.
      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-33; ASN-383 AND ASN-402
    16. 16.
      "Enrichment of glycopeptides for glycan structure and attachment site identification."
      Nilsson J. , Rueetschi U. , Halim A. , Hesse C. , Carlsohn E. , Brinkmalm G. , Larson G.
      Nat. Methods6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-109; ASN-383 AND ASN-402;STRUCTURE OF CARBOHYDRATES
      tissue: Cerebrospinal fluid.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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