Agrn ELISA Kit for Mouse(Mus musculus) | EIAab.comAgrn ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Agrn(Gene name) > Mouse

Agrn (Gene name),

Agrin (Protein name ), AGRIN_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Agrn(Agrin);

Protein name:

Agrin;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds to laminin.

Function:

Component of the basal lamina that causes the aggregation of acetylcholine receptors and acetylcholine-esterase on the surface of muscle fibers of the neuromuscular junction.

Subcellular Location:

Secreted extracellular space extracellular matrix Synaptic basal lamina at the neuromuscular junction.

Protein Attributes:

Sequence length:

1950

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1450:

1500:

1550:

1600:

1650:

1700:

1750:

1800:

1850:

1900:

1950:

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

Pfam:

PF00008

SMR:

A2ASQ1

String:

A2ASQ1

UniGene:

Mm.273098

Uniprot:

A2ASQ1

FOR

ELISA Kit for Mouse Agrin

Cat.:

E1303m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse Agrin

Cat.:

E1303r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Mouse Agrin

Cat.:

E1303h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Mouse Agrin

Cat.:

E1303c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Agrin

Cat.:

U1303r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Agrin

Cat.:

U1303c

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Agrin

Cat.:

U1303h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

CLIA Kit for Mouse Agrin

Cat.:

U1303m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Mouse Agrin

Cat.:

P1303Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Agrin

Cat.:

P1303Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Agrin

Cat.:

P1303Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Agrin

Monoclonal Antibody for Mouse Agrin

Protein for Mouse Agrin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
tissue: Brain.
3.

"Agrin acts via a MuSK receptor complex."
Glass D.J. , Bowen D.C. , Stitt T.N. , Radziejewski C. , Bruno J. , Ryan T.E. , Gies D.R. , Shah S. , Mattsson K. , Burden S.J. , DiStefano P.S. , Valenzuela D.M. , DeChiara T.M. , Yancopoulos G.D.
Cell85:513-523(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEUROMUSCULAR JUNCTION DEVELOPMENT;SUBCELLULAR LOCATION;FUNCTION IN PHOSPHORYLATION OF MUSK;INTERACTION WITH LRP4
4.

"Selective regulation of agrin mRNA induction and alternative splicing in PC12 cells by Ras-dependent actions of nerve growth factor."
Smith M.A. , Fanger G.R. , O'Connor L.T. , Bridle P. , Maue R.A.
J. Biol. Chem.272:15675-15681(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REGULATION OF ALTERNATIVE SPLICING
5.

"Interaction of agrin with laminin requires a coiled-coil conformation of the agrin-binding site within the laminin gamma1 chain."
Kammerer R.A. , Schulthess T. , Landwehr R. , Schumacher B. , Lustig A. , Yurchenco P.D. , Ruegg M.A. , Engel J. , Denzer A.J.
EMBO J.18:6762-6770(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LAMININ BINDING
6.

"Alternatively spliced isoforms of nerve- and muscle-derived agrin: their roles at the neuromuscular junction."
Burgess R.W. , Nguyen Q.T. , Son Y.J. , Lichtman J.W. , Sanes J.R.
Neuron23:33-44(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;FUNCTION
7.

"Agrin isoforms with distinct amino termini: differential expression, localization, and function."
Burgess R.W. , Skarnes W.C. , Sanes J.R.
J. Cell Biol.151:41-52(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;FUNCTION
8.

"An alternative amino-terminus expressed in the central nervous system converts agrin to a type II transmembrane protein."
Neumann F.R. , Bittcher G. , Annies M. , Schumacher B. , Kroger S. , Ruegg M.A.
Mol. Cell. Neurosci.17:208-225(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;SUBCELLULAR LOCATION
9.

"The COOH-terminal domain of agrin signals via a synaptic receptor in central nervous system neurons."
Hoover C.L. , Hilgenberg L.G. , Smith M.A.
J. Cell Biol.161:923-932(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF AGRIN C-TERMINAL 22 KDA FRAGMENT;SUBCELLULAR LOCATION
10.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
11.

"Synapse loss in cortex of agrin-deficient mice after genetic rescue of perinatal death."
Ksiazek I. , Burkhardt C. , Lin S. , Seddik R. , Maj M. , Bezakova G. , Jucker M. , Arber S. , Caroni P. , Sanes J.R. , Bettler B. , Ruegg M.A.
J. Neurosci.27:7183-7195(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;FUNCTION
12.

"Neurotrypsin cleaves agrin locally at the synapse."
Stephan A. , Mateos J.M. , Kozlov S.V. , Cinelli P. , Kistler A.D. , Hettwer S. , Rulicke T. , Streit P. , Kunz B. , Sonderegger P.
FASEB J.22:1861-1873(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING;IDENTIFICATION OF PROTEOLYTICALLY CLEAVED FRAGMENTS BY MASS SPECTROMETRY;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
13.

"Coincident pre- and postsynaptic activation induces dendritic filopodia via neurotrypsin-dependent agrin cleavage."
Matsumoto-Miyai K. , Sokolowska E. , Zurlinden A. , Gee C.E. , Luscher D. , Hettwer S. , Wolfel J. , Ladner A.P. , Ster J. , Gerber U. , Rulicke T. , Kunz B. , Sonderegger P.
Cell136:1161-1171(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING;FUNCTION
14.

"Rescuing Z+ agrin splicing in Nova null mice restores synapse formation and unmasks a physiologic defect in motor neuron firing."
Ruggiu M. , Herbst R. , Kim N. , Jevsek M. , Fak J.J. , Mann M.A. , Fischbach G. , Burden S.J. , Darnell R.B.
Proc. Natl. Acad. Sci. U.S.A.106:3513-3518(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REGULATION OF ALTERNATIVE SPLICING AT THE Z SITE
15.

"Destabilization of the neuromuscular junction by proteolytic cleavage of agrin results in precocious sarcopenia."
Butikofer L. , Zurlinden A. , Bolliger M.F. , Kunz B. , Sonderegger P.
FASEB J.25:4378-4393(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING;FUNCTION;MOUSE MODEL OF PRECOCIOUS SARCOPENIA
16.

"A valid mouse model of AGRIN-associated congenital myasthenic syndrome."
Bogdanik L.P. , Burgess R.W.
Hum. Mol. Genet.20:4617-4633(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT A MUTANT STRAIN SER-1061;CHARACTERIZATION OF A MOUSE MODEL OF AGRIN-ASSOCIATED CONGENITAL MYASTHENIC SYNDROME
17.

"Structural and biophysical characterisation of agrin laminin G3 domain constructs."
Tidow H. , Mattle D. , Nissen P.
Protein Eng. Des. Sel.24:219-224(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURAL CHARACTERISTICS OF LAMININ G3 DOMAIN
18.

"Crystal structure of the g2 domain of agrin from Mus musculus."
New York structural genomix research consortium (NYSGXRC)
Submitted (2011-01) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS) OF 1510-1701

Product Feedback Wall

* Email:
*Comments: