Gene name:
AGTR1 (AGTR1A;AGTR1B;AT2R1;AT2R1B) ;
Protein name:
Type-1 angiotensin II receptor ;
Alternative:
AT1BR ;AT1AR ;Angiotensin II type-1 receptor (AT1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with MAS1 (Probable). Interacts with ARRB1.
Function:
Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MILNSSTEDG | IKRIQDDCPK | AGRHNYIFVM | IPTLYSIIFV | VGIFGNSLVV |
100:
IVIYFYMKLK | TVASVFLLNL | ALADLCFLLT | LPLWAVYTAM | EYRWPFGNYL |
150:
CKIASASVSF | NLYASVFLLT | CLSIDRYLAI | VHPMKSRLRR | TMLVAKVTCI |
200:
IIWLLAGLAS | LPAIIHRNVF | FIENTNITVC | AFHYESQNST | LPIGLGLTKN |
250:
ILGFLFPFLI | ILTSYTLIWK | ALKKAYEIQK | NKPRNDDIFK | IIMAIVLFFF |
300:
FSWIPHQIFT | FLDVLIQLGI | IRDCRIADIV | DTAMPITICI | AYFNNCLNPL |
350:
FYGFLGKKFK | RYFLQLLKYI | PPKAKSHSNL | STKMSTLSYR | PSDNVSSSTK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Dog
Rabbit
Chicken
Bovine
Pig
ELISA Kit for Human Type-1 angiotensin II receptor
ELISA Kit for Human Type-1 angiotensin II receptor
ELISA Kit for Human Type-1 angiotensin II receptor
ELISA Kit for Human Type-1 angiotensin II receptor
ELISA Kit for Human Type-1 angiotensin II receptor
ELISA Kit for Human Type-1 angiotensin II receptor
ELISA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
CLIA Kit for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Polyclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Monoclonal Antibody for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
Protein for Human Type-1 angiotensin II receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue :
Lymphocyte .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
4.
"Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor."
Takayanagi R.
,
Ohnaka K.
,
Sakai Y.
,
Nakao R.
,
Yanase T.
,
Haji M.
,
Inagami T.
,
Furuta H.
,
Gou D.F.
,
Nakamuta M.
,
Nawata H.
Biochem. Biophys. Res. Commun.183:910-916(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT TRP-289
tissue :
Placenta .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
8.
"Cloning and sequencing of a human cDNA encoding the angiotensin II receptor type 1."
Ostermann E.
,
Castanon M.J.
Submitted (1994-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Placenta .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
10.
"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Kopatz S.A.
,
Aronstam R.S.
,
Sharma S.V.
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS VAL-222 AND HIS-341
tissue :
Brain .
12.
"G-protein-coupled receptor Mas is a physiological antagonist of the angiotensin II type 1 receptor."
Kostenis E.
,
Milligan G.
,
Christopoulos A.
,
Sanchez-Ferrer C.F.
,
Heringer-Walther S.
,
Sexton P.M.
,
Gembardt F.
,
Kellett E.
,
Martini L.
,
Vanderheyden P.
,
Schultheiss H.P.
,
Walther T.
Circulation111:1806-1813(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH MAS1
13.
"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W.
,
Lu Z.
,
Fu Y.
,
Wang H.P.
,
Wang L.H.
,
Chi H.
,
Yuan Z.F.
,
Zheng Z.B.
,
Song L.N.
,
Han H.H.
,
Liang Y.M.
,
Wang J.L.
,
Cai Y.
,
Zhang Y.K.
,
Deng Y.L.
,
Ying W.T.
,
He S.M.
,
Qian X.H.
Mol. Cell. Proteomics8:913-923(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-4
14.
"Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis."
Gribouval O.
,
Gonzales M.
,
Neuhaus T.
,
Aziza J.
,
Bieth E.
,
Laurent N.
,
Bouton J.M.
,
Feuillet F.
,
Makni S.
,
Ben Amar H.
,
Laube G.
,
Delezoide A.-L.
,
Bouvier R.
,
Dijoud F.
,
Ollagnon-Roman E.
,
Roume J.
,
Joubert M.
,
Antignac C.
,
Gubler M.-C.
more...
Nat. Genet.37:964-968(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT RTD MET-282