Ahrr ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAhrr ELISA Kit for Rat(Rattus norvegicus)

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Ahrr (Gene name),

Aryl hydrocarbon receptor repressor (Protein name ), AHRR_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ahrr;

Protein name:

Aryl hydrocarbon receptor repressor(AhR repressor;AhRR);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with ARNT, ANKRA2, HDAC4 and HDAC5.

Function:

Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Subcellular Location:

Cytoplasm Nucleus Predominantly in the nuclear compartment. First cytoplasmic, translocates into the nuclear compartment upon interaction with ARNT in the cytoplasmic compartment.

Protein Attributes:

Sequence length:

701

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

701:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q75NT5

KEGG:

rno:498999

UniGene:

Rn.145524

Pfam:

PF00010

STRING:

10116.ENSRNOP00000019806

Uniprot:

Q75NT5

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ELISA Kit for Rat AhR repressor

CLIA Kit for Rat AhR repressor

Polyclonal Antibody for Rat AhR repressor

Monoclonal Antibody for Rat AhR repressor

Protein for Rat AhR repressor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain."
Korkalainen M. , Tuomisto J. , Pohjanvirta R.
Biochem. Biophys. Res. Commun.315:123-131(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION
strain: Long Evans.
2.

"Primary structure and organ-specific expression of the rat aryl hydrocarbon receptor repressor gene."
Nishihashi H. , Kanno Y. , Tomuro K. , Nakahama T. , Inouye Y.
Biol. Pharm. Bull.29:640-647(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;INDUCTION
strain: Wistar.
tissue: Heart.

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