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Index > Protein center > Aif1(Gene name) > Rat
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  • Aif1 (Gene name),
  • Allograft inflammatory factor 1 (Protein name ),  AIF1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Aif1(Iba1;Mrf1);
    Protein name:
    Allograft inflammatory factor 1(AIF-1);
    Alternative:
    MRF-1;Ionized calcium-binding adapter molecule 1;Microglia response factor;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer (Potential). Monomer. Interacts with LCP1.
    Function:
    Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play an role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell projection ruffle membrane Peripheral membrane protein Cytoplasmic side Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
    Protein Attributes:
    Sequence length:
    147
    Sequence:
    50:
    MSQSKDLQGG | KAFGLLKAQQ | EERLDGINKH | FLDDPKYSSD | EDLQSKLEAF | 
    100:
    KTKYMEFDLN | GNGDIDIMSL | KRMLEKLGVP | KTHLELKKLI | REVSSGSEET | 
    147:
    FSYSDFLRMM | LGKRSAILRM | ILMYEEKNKE | HQKPTGPPAK | KAISELP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat AIF-1
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    E1251h
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    ELISA Kit for Rat AIF-1
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    E1251m
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    ELISA Kit for Rat AIF-1
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    E1251r
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    ELISA Kit for Rat AIF-1
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    E1251b
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    ELISA Kit for Rat AIF-1
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    E1251p
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    96T
    CLIA Kit for Rat AIF-1
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    U1251h
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    96T
    CLIA Kit for Rat AIF-1
    Cat.:
    U1251r
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    96T
    CLIA Kit for Rat AIF-1
    Cat.:
    U1251b
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    Packing:
    96T
    CLIA Kit for Rat AIF-1
    Cat.:
    U1251p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat AIF-1
    Cat.:
    U1251m
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    Packing:
    96T
    Polyclonal Antibody for Rat AIF-1
    Polyclonal Antibody for Rat AIF-1
    Cat.:
    P1251Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat AIF-1
    Polyclonal Antibody for Rat AIF-1
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    P1251Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat AIF-1
    Cat.:
    P1251Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat AIF-1
    Monoclonal Antibody for Rat AIF-1
    Monoclonal Antibody for Rat AIF-1
    Monoclonal Antibody for Rat AIF-1
    Monoclonal Antibody for Rat AIF-1
    Protein for Rat AIF-1
    Protein for Rat AIF-1
    Protein for Rat AIF-1
    Protein for Rat AIF-1
    Protein for Rat AIF-1

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    References
    1. 1.
      "Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection."
      Utans U. , Arceci R.J. , Yamashita Y. , Russell M.E.
      J. Clin. Invest.95:2954-2962(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Lewis.
      tissue: Heart.
    2. 2.
      "Use of differential display to identify differentially expressed mRNAs induced by rat carotid artery balloon angioplasty."
      Autieri M.V. , Feuerstein G.Z. , Yue T.-L. , Ohlstein E.H. , Douglas S.A.
      Lab. Invest.72:656-661(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Testis.
    3. 3.
      "A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage."
      Imai Y. , Ibata I. , Ito D. , Ohsawa K. , Kohsaka S.
      Biochem. Biophys. Res. Commun.224:855-862(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Wistar.
      tissue: Testis.
    4. 4.
      "Upregulation of a new microglial gene, mrf-1, in response to programmed neuronal cell death and degeneration."
      Tanaka S. , Suzuki K. , Watanabe M. , Matsuda A. , Tone S. , Koike T.
      J. Neurosci.18:6358-6369(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "The genomic sequence and comparative analysis of the rat major histocompatibility complex."
      Hurt P. , Walter L. , Sudbrak R. , Klages S. , Mueller I. , Shiina T. , Inoko H. , Lehrach H. , Guenther E. , Reinhardt R. , Himmelbauer H.
      Genome Res.14:631-639(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
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