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Index > Protein center > Aim2(Gene name) > Mouse
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  • Aim2 (Gene name),
  • Interferon-inducible protein AIM2 (Protein name ),  AIM2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Aim2(Gm1313;Ifi210);
    Protein name:
    Interferon-inducible protein AIM2;
    Alternative:
    Interferon-inducible protein p210;Interferon-inducible protein 210(Ifi-210);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    N/A
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    354
    Sequence:
    50:
    MESEYREMLL | LTGLDHITEE | ELKRFKYFAL | TEFQIARSTL | DVADRTELAD | 
    100:
    HLIQSAGAAS | AVTKAINIFQ | KLNYMHIANA | LEEKKKEAER | KLMTNTKKRG | 
    150:
    TQKVENRSQA | ENCSAASATR | SDNDFKEQAA | TEVCPQAKPQ | KKQMVAEQEA | 
    200:
    IREDLQKDPL | VVTVLKAINP | FECETQEGRQ | EIFHATVATE | TDFFFVKVLN | 
    250:
    AQFKDKFIPK | RTIKISNYLW | HSNFMEVTSS | SVVVDVESNH | EVPNNVVKRA | 
    300:
    RETPRISKLK | IQPCGTIVNG | LFKVQKITEE | KDRVLYGIHD | KTGTMEVLVL | 
    350:
    GNPSKTKCEE | GDKIRLTFFE | VSKNGVKIQL | KSGPCSFFKV | IKAAKPKTDM | 
    354:
    KSVE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Interferon-inducible protein AIM2
    Cat.:
    E2139h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Mouse Interferon-inducible protein AIM2
    Cat.:
    E2139m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Interferon-inducible protein AIM2
    Cat.:
    U2139h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Interferon-inducible protein AIM2
    Cat.:
    U2139m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Interferon-inducible protein AIM2
    Cat.:
    P2139Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Interferon-inducible protein AIM2
    Cat.:
    P2139Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Interferon-inducible protein AIM2
    Monoclonal Antibody for Mouse Interferon-inducible protein AIM2
    Protein for Mouse Interferon-inducible protein AIM2
    Protein for Mouse Interferon-inducible protein AIM2

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 219-354
      strain: FVB/N.
      tissue: Mammary tumor.
    3. 3.
      "The HIN-200 family: more than interferon-inducible genes?"
      Ludlow L.E.A. , Johnstone R.W. , Clarke C.J.P.
      Exp. Cell Res.308:1-17(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
    4. 4.
      "AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA."
      Fernandes-Alnemri T. , Yu J.W. , Datta P. , Wu J. , Alnemri E.S.
      Nature458:509-513(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC."
      Hornung V. , Ablasser A. , Charrel-Dennis M. , Bauernfeind F. , Horvath G. , Caffrey D.R. , Latz E. , Fitzgerald K.A.
      Nature458:514-518(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA."
      Roberts T.L. , Idris A. , Dunn J.A. , Kelly G.M. , Burnton C.M. , Hodgson S. , Hardy L.L. , Garceau V. , Sweet M.J. , Ross I.L. , Hume D.A. , Stacey K.J.
      Science323:1057-1060(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol."
      Sauer J.D. , Witte C.E. , Zemansky J. , Hanson B. , Lauer P. , Portnoy D.A.
      Cell Host Microbe7:412-419(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "The AIM2 inflammasome is critical for innate immunity to Francisella tularensis."
      Fernandes-Alnemri T. , Yu J.W. , Juliana C. , Solorzano L. , Kang S. , Wu J. , Datta P. , McCormick M. , Huang L. , McDermott E. , Eisenlohr L. , Landel C.P. , Alnemri E.S.
      Nat. Immunol.11:385-393(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    9. 9.
      "The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses."
      Rathinam V.A. , Jiang Z. , Waggoner S.N. , Sharma S. , Cole L.E. , Waggoner L. , Vanaja S.K. , Monks B.G. , Ganesan S. , Latz E. , Hornung V. , Vogel S.N. , Szomolanyi-Tsuda E. , Fitzgerald K.A.
      Nat. Immunol.11:395-402(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    10. 10.
      "Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis."
      Jones J.W. , Kayagaki N. , Broz P. , Henry T. , Newton K. , O'Rourke K. , Chan S. , Dong J. , Qu Y. , Roose-Girma M. , Dixit V.M. , Monack D.M.
      Proc. Natl. Acad. Sci. U.S.A.107:9771-9776(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    11. 11.
      "AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages."
      Pierini R. , Juruj C. , Perret M. , Jones C.L. , Mangeot P. , Weiss D.S. , Henry T.
      Cell Death Differ.19:1709-1721(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    12. 12.
      "Francisella infection triggers activation of the AIM2 inflammasome in murine dendritic cells."
      Belhocine K. , Monack D.M.
      Cell. Microbiol.14:71-80(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    13. 13.
      "Structural basis for termination of AIM2-mediated signaling by p202."
      Ru H. , Ni X. , Zhao L. , Crowley C. , Ding W. , Hung L.W. , Shaw N. , Cheng G. , Liu Z.J.
      Cell Res.23:855-858(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.22 ANGSTROMS) OF 158-349 IN COMPLEX WITH DNA;FUNCTION;DOMAIN;DNA-BINDING
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