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Index > Protein center > AJAP1(Gene name) > Human
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  • AJAP1 (Gene name),
  • Adherens junction-associated protein 1 (Protein name ),  AJAP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AJAP1(MOT8;SHREW1);
    Protein name:
    Adherens junction-associated protein 1;
    Alternative:
    Membrane protein shrew-1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms a complex with CDH1 and CTNNB1; interacts directly with CTNNB1. Interacts with AP1M2 and BSG/CD147.
    Function:
    Plays a role in cell adhesion and cell migration.
    Subcellular Location:
    Basolateral cell membrane Single-pass type III membrane protein Apical cell membrane Single-pass type III membrane protein Cell junction adherens junction Mainly basolateral. Localization is mediated by AP1M2.
    Protein Attributes:
    Sequence length:
    411
    Sequence:
    50:
    MWIQQLLGLS | SMSIRWPGRP | LGSHAWILIA | MFQLAVDLPA | CEALGPGPEF | 
    100:
    WLLPRSPPRP | PRLWSFRSGQ | PARVPAPVWS | PRPPRVERIH | GQMQMPRARR | 
    150:
    AHRPRDQAAA | LVPKAGLAKP | PAAAKSSPSL | ASSSSSSSSA | VAGGAPEQQA | 
    200:
    LLRRGKRHLQ | GDGLSSFDSR | GSRPTTETEF | IAWGPTGDEE | ALESNTFPGV | 
    250:
    YGPTTVSILQ | TRKTTVAATT | TTTTTATPMT | LQTKGFTESL | DPRRRIPGGV | 
    300:
    STTEPSTSPS | NNGEVTQPPR | ILGEASGLAV | HQIITITVSL | IMVIAALITT | 
    350:
    LVLKNCCAQS | GNTRRNSHQR | KTNQQEESCQ | NLTDFPSARV | PSSLDIFTAY | 
    400:
    NETLQCSHEC | VRASVPVYTD | ETLHSTTGEY | KSTFNGNRPS | SSDRHLIPVA | 
    411:
    FVSEKWFEIS | C
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Adherens junction-associated protein 1
    ELISA Kit for Human Adherens junction-associated protein 1
    ELISA Kit for Human Adherens junction-associated protein 1
    CLIA Kit for Human Adherens junction-associated protein 1
    CLIA Kit for Human Adherens junction-associated protein 1
    CLIA Kit for Human Adherens junction-associated protein 1
    Polyclonal Antibody for Human Adherens junction-associated protein 1
    Polyclonal Antibody for Human Adherens junction-associated protein 1
    Polyclonal Antibody for Human Adherens junction-associated protein 1
    Monoclonal Antibody for Human Adherens junction-associated protein 1
    Monoclonal Antibody for Human Adherens junction-associated protein 1
    Monoclonal Antibody for Human Adherens junction-associated protein 1
    Protein for Human Adherens junction-associated protein 1
    Protein for Human Adherens junction-associated protein 1
    Protein for Human Adherens junction-associated protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Novel membrane protein shrew-1 targets to cadherin-mediated junctions in polarized epithelial cells."
      Bharti S. , Handrow-Metzmacher H. , Zickenheiner S. , Zeitvogel A. , Baumann R. , Starzinski-Powitz A.
      Mol. Biol. Cell15:397-406(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;SUBCELLULAR LOCATION;TOPOLOGY;INTERACTION WITH CDH1 AND CTNNB1
      tissue: Brain.
    2. 2.
      "Identification of genes differentially expressed in HT1080 human fibrosarcoma cells selected for invasive capacity in vitro."
      Kudoh S. , Chung I.M. , Tsuiji M. , Tsuji T. , Irimura T.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Fibrosarcoma.
    3. 3.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      Rhodes S.
      Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 179-411
    5. 5.
      "The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration."
      McDonald J.M. , Dunlap S. , Cogdell D. , Dunmire V. , Wei Q. , Starzinski-Powitz A. , Sawaya R. , Bruner J. , Fuller G.N. , Aldape K. , Zhang W.
      Cancer Biol. Ther.5:300-304(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;VARIANT ARG-263
    6. 6.
      "Targeting of transmembrane protein shrew-1 to adherens junctions is controlled by cytoplasmic sorting motifs."
      Jakob V. , Schreiner A. , Tikkanen R. , Starzinski-Powitz A.
      Mol. Biol. Cell17:3397-3408(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MUTAGENESIS OF LEU-303; TYR-350; TYR-368; TYR-380; LEU-396 AND 396-LEU--ILE-397;INTERACTION WITH AP1M2
    7. 7.
      "junction protein shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147."
      Schreiner A. , Ruonala M. , Jakob V. , Suthaus J. , Boles E. , Wouters F. , Starzinski-Powitz A.
      Mol. Biol. Cell18:1272-1281(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH BSG
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