Gene name:
AKAP8L (HRIHFB2018;NAKAP;NAKAP95) ;
Protein name:
A-kinase anchor protein 8-like (AKAP8-like protein) ;
Alternative:
Homologous to AKAP95 protein (HA95) ;Helicase A-binding protein 95 (HAP95) ;Neighbor of A-kinase-anchoring protein 95 (Neighbor of AKAP95) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with PRPF40A (By similarity). Binds to the C-terminal of RNA helicase A and to TMPO-beta. Interacts with RNF43.
Function:
Could play a role in constitutive transport element (CTE)-mediated gene expression. Does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May regulate the initiation phase of DNA replication when associated with TMPO-beta.
Subcellular Location:
Nucleus matrix
Cytoplasm
Colocalizes with PRPF40A in the nuclear matrix (By similarity). Nuclear at steady state but shuttles between the nucleus and cytoplasm. Associated with the nuclear matrix.
Protein Attributes:
50:
MSYTGFVQGS | ETTLQSTYSD | TSAQPTCDYG | YGTWNSGTNR | GYEGYGYGYG |
100:
YGQDNTTNYG | YGMATSHSWE | MPSSDTNANT | SASGSASADS | VLSRINQRLD |
150:
MVPHLETDMM | QGGVYGSGGE | RYDSYESCDS | RAVLSERDLY | RSGYDYSELD |
200:
PEMEMAYEGQ | YDAYRDQFRM | RGNDTFGPRA | QGWARDARSG | RPMASGYGRM |
250:
WEDPMGARGQ | CMSGASRLPS | LFSQNIIPEY | GMFQGMRGGG | AFPGGSRFGF |
300:
GFGNGMKQMR | RTWKTWTTAD | FRTKKKKRKQ | GGSPDEPDSK | ATRTDCSDNS |
350:
DSDNDEGTEG | EATEGLEGTE | AVEKGSRVDG | EDEEGKEDGR | EEGKEDPEKG |
400:
ALTTQDENGQ | TKRKLQAGKK | SQDKQKKRQR | DRMVERIQFV | CSLCKYRTFY |
450:
EDEMASHLDS | KFHKEHFKYV | GTKLPKQTAD | FLQEYVTNKT | KKTEELRKTV |
500:
EDLDGLIHQI | YRDQDLTQEI | AMEHFVKKVE | AAHCAACDLF | IPMQFGIIQK |
550:
HLKTMDHNRN | RRLMMEQSKK | SSLMVARSIL | NNKLISKKLE | RYLKGENPFT |
600:
DSPEEEKEQE | EAEGGALDEG | AQGEAAGISE | GAEGVPAQPP | VPPEPAPGAV |
646:
SPPPPPPPEE | EEEGAVPLLG | GALQRQIRGI | PGLDVEDDEE | GGGGAP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human AKAP8-like protein
ELISA Kit for Human AKAP8-like protein
CLIA Kit for Human AKAP8-like protein
CLIA Kit for Human AKAP8-like protein
Polyclonal Antibody for Human AKAP8-like protein
Polyclonal Antibody for Human AKAP8-like protein
Monoclonal Antibody for Human AKAP8-like protein
Monoclonal Antibody for Human AKAP8-like protein
Protein for Human AKAP8-like protein
Protein for Human AKAP8-like protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT GLN-458
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Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT GLN-458
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLN-458
tissue :
Placenta .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-358 (ISOFORM 1);SUBCELLULAR LOCATION
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Fetal brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-283;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT [LARGE SCALE ANALYSIS] GLN-458;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]