Protein name:
ALS2 C-terminal-like protein ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homodimer. Forms a heteromeric complex with ALS2. Interacts with ALS2 and RAB5A.
Function:
Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics.
Subcellular Location:
Cytoplasm
Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells.
Protein Attributes:
50:
MCSPEEAALL | RLEEVFSATL | ARINSLVFQP | LLEAGPEASD | PWGRECLQLL |
100:
QQLHSSSQQL | WDVMEESLHS | LRERLRRPEA | VGLESLLLLQ | SADRVLQVHL |
150:
EYIESYTCCV | AVQAFQKAVK | RRSEYWRGQR | KALRQVLSGL | SSEGSVGTAL |
200:
LQALRQPLAH | HVQQYVLLLL | SLGDTVGECH | PTRELVIHAA | SLFGDLQSFM |
250:
RQELDQATAT | QALWPTLSSR | LRDVLCTPAR | RLLQDSQDVP | VTVTPLRAER |
300:
VLLFDDALVL | LQGHNIHTFD | LKLVWVEPGQ | DRCTFHLLTP | EEGFSFCSKD |
350:
PQGLVVWQWK | VTQAVCQALR | GKKDFPVLGA | GLEPSEPPTC | RCGAYTFHAE |
400:
GRFCQATYEG | EWYWGRPHGK | GTLKWPDGRN | HVGDFCQGLE | HGFGIRLVPQ |
450:
ASEDKFDCYK | CHWWEGSMCG | YGICEYSTSE | VYKGYFQEGL | RHGFGVLESA |
500:
PQAPRPLRYT | GHWERGQRSG | YGVEEDSDRG | ERYIGMWQAD | QRHGPGVMVT |
550:
QAGVCYQGTF | QADKMVGPGI | LLSDDDSLYE | GTFTRDLTLV | GKGKVTFPNG |
600:
FTLEGSFGSV | SGRGLHTQGV | LDTAALPPDP | SSTCKRQLGQ | GVFPVESRWQ |
650:
GVYGAFRDFV | RAGCPGDLRE | ALLGFHVQSS | RELRKSQEYL | CCERTCPEDQ |
700:
AGRMEDLLEE | LLQHREPEAL | QQCLRKALSN | SLHPLGKLLR | TLMLTFQATY |
750:
AGIGANKHLQ | GLAQEEVKQH | AQELWAAYRG | LLQVALQRKG | QAPEEDEDAE |
800:
TRDLRVHSLV | LPLVLPSFYS | ELFTLYLLLH | EREDSLYSQG | ITHLSLFPDA |
850:
RLLEFLDVQK | HLWPLKDLTL | TTNQRYSLVR | DKCFLSATEC | LQKMITTVDP |
900:
REKLEVLERT | YGEIEATVSR | VLGREHKLPM | DDLLPLLIYV | VSRAQIQHLG |
950:
AEIHLIRDMM | DPLHTGGLYD | FLLTALESCY | EHIQKEDMRL | HRLPSRWSSR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
ELISA Kit for Bovine ALS2 C-terminal-like protein
ELISA Kit for Bovine ALS2 C-terminal-like protein
ELISA Kit for Bovine ALS2 C-terminal-like protein
CLIA Kit for Bovine ALS2 C-terminal-like protein
CLIA Kit for Bovine ALS2 C-terminal-like protein
CLIA Kit for Bovine ALS2 C-terminal-like protein
Polyclonal Antibody for Bovine ALS2 C-terminal-like protein
Polyclonal Antibody for Bovine ALS2 C-terminal-like protein
Polyclonal Antibody for Bovine ALS2 C-terminal-like protein
Monoclonal Antibody for Bovine ALS2 C-terminal-like protein
Monoclonal Antibody for Bovine ALS2 C-terminal-like protein
Monoclonal Antibody for Bovine ALS2 C-terminal-like protein
Protein for Bovine ALS2 C-terminal-like protein
Protein for Bovine ALS2 C-terminal-like protein
Protein for Bovine ALS2 C-terminal-like protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal skin .