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Index > Protein center > ALDH2(Gene name) > Human
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  • ALDH2 (Gene name),
  • Aldehyde dehydrogenase, mitochondrial (Protein name ),  ALDH2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ALDH2(ALDM);
    Protein name:
    Aldehyde dehydrogenase, mitochondrial;
    Alternative:
    ALDH-E2;ALDH class 2;ALDHI;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    517
    Sequence:
    50:
    MLRAAARFGP | RLGRRLLSAA | ATQAVPAPNQ | QPEVFCNQIF | INNEWHDAVS | 
    100:
    RKTFPTVNPS | TGEVICQVAE | GDKEDVDKAV | KAARAAFQLG | SPWRRMDASH | 
    150:
    RGRLLNRLAD | LIERDRTYLA | ALETLDNGKP | YVISYLVDLD | MVLKCLRYYA | 
    200:
    GWADKYHGKT | IPIDGDFFSY | TRHEPVGVCG | QIIPWNFPLL | MQAWKLGPAL | 
    250:
    ATGNVVVMKV | AEQTPLTALY | VANLIKEAGF | PPGVVNIVPG | FGPTAGAAIA | 
    300:
    SHEDVDKVAF | TGSTEIGRVI | QVAAGSSNLK | RVTLELGGKS | PNIIMSDADM | 
    350:
    DWAVEQAHFA | LFFNQGQCCC | AGSRTFVQED | IYDEFVERSV | ARAKSRVVGN | 
    400:
    PFDSKTEQGP | QVDETQFKKI | LGYINTGKQE | GAKLLCGGGI | AADRGYFIQP | 
    450:
    TVFGDVQDGM | TIAKEEIFGP | VMQILKFKTI | EEVVGRANNS | TYGLAAAVFT | 
    500:
    KDLDKANYLS | QALQAGTVWV | NCYDVFGAQS | PFGGYKMSGS | GRELGEYGLQ | 
    517:
    AYTEVKTVTV | KVPQKNS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    MIM:
    KEGG:
    UniGene:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    ELISA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    ELISA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    ELISA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    ELISA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    CLIA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    CLIA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    CLIA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    CLIA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    CLIA Kit for Human Aldehyde dehydrogenase, mitochondrial
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    Packing:
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    Polyclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Polyclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
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    Polyclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Polyclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
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    Polyclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
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    Packing:
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    Monoclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Monoclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Monoclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Monoclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Monoclonal Antibody for Human Aldehyde dehydrogenase, mitochondrial
    Protein for Human Aldehyde dehydrogenase, mitochondrial
    Protein for Human Aldehyde dehydrogenase, mitochondrial
    Protein for Human Aldehyde dehydrogenase, mitochondrial
    Protein for Human Aldehyde dehydrogenase, mitochondrial
    Protein for Human Aldehyde dehydrogenase, mitochondrial

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    References
    1. 1.
      "Evidence for a signal peptide at the amino-terminal end of human mitochondrial aldehyde dehydrogenase."
      Braun T. , Bober E. , Singh S. , Agarwal D.P. , Goedde H.W.
      FEBS Lett.215:233-236(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Muscle.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;SEQUENCE REVISION TO N-TERMINUS
    3. 3.
      "Isolation and sequence analysis of a full length cDNA clone coding for human mitochondrial aldehyde dehydrogenase."
      Braun T. , Bober E. , Singh S. , Agarwal D.P. , Goedde H.W.
      Nucleic Acids Res.15:3179-3179(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Muscle.
    4. 4.
      "Genomic structure of the human mitochondrial aldehyde dehydrogenase gene."
      Hsu L.C. , Bendel R.E. , Yoshida A.
      Genomics2:57-65(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      Lassen N. , Estey T. , Vasiliou V.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    7. 7.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Synovium.
    8. 8.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Lymph.
    10. 10.
      "Mitochondrial aldehyde dehydrogenase from human liver. Primary structure, differences in relation to the cytosolic enzyme, and functional correlations."
      Hempel J. , Kaiser R. , Joernvall H.
      Eur. J. Biochem.153:13-28(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-517 (ISOFORM 1)
      tissue: Liver.
    11. 11.
      "Cloning of cDNAs for human aldehyde dehydrogenases 1 and 2."
      Hsu L.C. , Tani K. , Fujiyoshi T. , Kurachi K. , Yoshida A.
      Proc. Natl. Acad. Sci. U.S.A.82:3771-3775(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 119-517 (ISOFORM 1)
      tissue: Liver.
    12. 12.
      "Molecular abnormality and cDNA cloning of human aldehyde dehydrogenases."
      Yoshida A. , Ikawa M. , Hsu L.C. , Tani K.
      Alcohol2:103-106(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 119-517 (ISOFORM 1)
    13. 13.
      Lubec G. , Vishwanath V.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 160-172 AND 325-338;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
    14. 14.
      "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
      Aboulaich N. , Vainonen J.P. , Stralfors P. , Vener A.V.
      Biochem. J.383:237-248(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 196-226 AND 325-338
      tissue: Adipocyte.
    15. 15.
      "Human aldehyde dehydrogenase isozymes and alcohol sensitivity."
      Agarwal D.P. , Goedde H.W.
      Isozymes Curr. Top. Biol. Med. Res.16:21-48(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 214-500;VARIANT VAL-337
      tissue: Liver.
    16. 16.
      "Mitochondrial aldehyde dehydrogenase. Homology of putative targeting sequence to that of carbamyl phosphate synthetase I revealed by correlation of cDNA and protein data."
      Hempel J. , Hoeoeg J.-O. , Joernvall H.
      FEBS Lett.222:95-98(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DESCRIPTION OF ORIGIN OF CONFLICTS BETWEEN THE SEQUENCE DESCRIBED IN PUBMED:4065146 AND DNA SEQUENCES
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "Human liver mitochondrial aldehyde dehydrogenase: three-dimensional structure and the restoration of solubility and activity of chimeric forms."
      Ni L. , Zhou J. , Hurley T.D. , Weiner H.
      Protein Sci.8:2784-2790(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.58 ANGSTROMS)
    19. 19.
      "Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals."
      Yoshida A. , Huang I.-Y. , Ikawa M.
      Proc. Natl. Acad. Sci. U.S.A.81:258-261(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LYS-504
    20. 20.
      "Mitochondrial aldehyde dehydrogenase polymorphism in Asian and American Indian populations: detection of new ALDH2 alleles."
      Novoradovsky A. , Tsai S.J. , Goldfarb L. , Peterson R. , Long J.C. , Goldman D.
      Alcohol. Clin. Exp. Res.19:1105-1110(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LYS-496
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