Protein name:
Alsin ;
Alternative:
Amyotrophic lateral sclerosis 2 protein homolog ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Forms a heteromeric complex with ALS2CL. Interacts with ALS2CL.
Function:
May act as a GTPase regulator (By similarity). Controls survival and growth of spinal motoneurons.
Subcellular Location:
N/A
Protein Attributes:
50:
MDSKKKSSTE | AEGSKERGLV | HVWQAGSFSL | TPERLPGWGG | KTVLQAALGV |
100:
RHGVLLTEDG | EVYSFGTLPW | KSESAEICPS | SPLLESALVG | HHVITVATGS |
150:
FHSGAVTESG | VVYMWGENAA | GQCAVANQQY | VPEPSPVSIS | DSETSPSLAV |
200:
RILQLACGEE | HTLALSLSRE | IWAWGTGCQL | GLITTTFPVT | KPQKVEHLAG |
250:
RVVLQVACGA | FHSLALVQCL | PPQDLKPVPE | RCNQCSQLLI | TMTDKEDHVI |
300:
ISDSHCCPLG | VTLSESQAEK | HASPAPSPHP | EALDEQGEVF | ENTVVEAELN |
350:
MGSSQTTSGS | AISTQQNIVG | TAEVSSARTA | PSYPDTHAVT | AYLQKLSEHS |
400:
MRENHEPGEK | PPQVQPLVEE | AVPDLHSPPT | TSTSALNSLV | VSCASAVGVR |
450:
VAATYEAGAL | SLKKVMNFYS | TAPCETAAQS | GSASTGPESL | KDLREEQVKQ |
500:
ESLQGKKSSS | LMDIREEESE | GGSRRLSLPG | LLSQVSPRLL | RKAARVKTRT |
550:
VVLTPTYSGE | ADALLPSLRT | EVWTWGKGKE | GQLGHGDVLP | RLQPLCVKCL |
600:
DGKEVIHLEA | GGSHSLALTA | KSQVYSWGSN | TFGQLGHSEF | PTTVPRLSKV |
650:
SSENGVWSVA | AGQDYSLFLV | DTEDFQPGLY | YSGRQDRAEG | DTLPENPSGT |
700:
KTPVLLSCSK | LGYISRVTAG | KDSYLALVDK | NIMGYIASLH | ELASTERRFY |
750:
SKLSEIKSQI | LRPLLSLENL | GTVTTVQLLQ | EVASRFSKLC | YLIGQHGASL |
800:
SSYLQGMKEA | SSLVIMKHSS | LFLDSYTEYC | TSVSNFLVMG | GFQLLAKPAI |
850:
DFLNKNQELL | QDLSEVNDEN | TQLMEILNML | FFLPIRRLHN | YAKVLLKLAT |
900:
CFEVTSPEYQ | KLQDSSSCYE | SLALHLGKKR | KEAEYTLSFW | KTFPGKMTDS |
950:
LRKPERRLLC | ESSNRALSLQ | HAGRFSVNWF | ILFNDALVHA | QFSTHHVFPL |
1000:
ATLWAEPLSE | EAGSVNGLKI | TTPEEQFTLI | SSTPQEKTKW | LRAISQAVDQ |
1050:
ALRGTSDFPL | YGGGSSVQRQ | EPPISRSAKY | TFYKDTRLKD | ATYDGRWLSG |
1100:
KPHGRGVLKW | PDGKMYSGMF | RNGLEDGYGE | YRIPNKALNK | EDHYVGHWKE |
1150:
GKMCGQGVYS | YASGEVFEGC | FQDNMRHGHG | LLRSGKLTSS | SPSMFIGQWV |
1200:
MDKKAGYGVF | DDITRGEKYM | GMWQDDVCQG | NGVVVTQFGL | YYEGNFHLNK |
1250:
MMGNGVLLSE | DDTIYEGEFS | DDWTLSGKGT | LTMPHGDYIE | GYFSGEWGSG |
1300:
IKITGTYFKP | SLYESDKDKP | KAFRKLGNLA | VAADEKWRAV | FEECWRQLGC |
1350:
ESPGQGEVWK | AWDNIAVALT | TNRRQHKDSP | EILSRSQTQT | LESLEYIPQH |
1400:
IGAFSVEKYD | DIKKYLIKAC | DTPLHPLGRL | VETLVAVYRM | TYVGVGANRR |
1450:
LLQEAVKEIK | SYLKRIFQLV | RFLFPELPEE | GSTIPLSAPL | PTGRRSFCTG |
1500:
KSDSRSESPE | PGYVVTSSGL | LLPVLLPRLY | PPLFMLYALD | NDREEDIYWE |
1550:
CVLRLNKQPD | IALLGFLGVQ | KKFWPATLSI | LGESKKVLST | TKDACFASAV |
1600:
ECLQQISTTF | TPSDKLKVIQ | QTFEEISQSV | LASLQEDFLW | SMDDLFPVFL |
1650:
YVVLRARIRN | LGSEVHLIED | LMDPFLQHGE | QGIMFTTLKA | CYFQIQREKL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse Alsin
ELISA Kit for Mouse Alsin
ELISA Kit for Mouse Alsin
Polyclonal Antibody for Mouse Alsin
Polyclonal Antibody for Mouse Alsin
Polyclonal Antibody for Mouse Alsin
Monoclonal Antibody for Mouse Alsin
Monoclonal Antibody for Mouse Alsin
Monoclonal Antibody for Mouse Alsin
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2."
Hadano S.
,
Hand C.K.
,
Osuga H.
,
Yanagisawa Y.
,
Otomo A.
,
Devon R.S.
,
Miyamoto N.
,
Showguchi-Miyata J.
,
Okada Y.
,
Singaraja R.
,
Figlewicz D.A.
,
Kwiatkowski T.
,
Hosler B.A.
,
Sagie T.
,
Skaug J.
,
Nasir J.
,
Brown R.H. Jr.
,
Scherer S.W.
,
Rouleau G.A.
,
Hayden M.R.
,
Ikeda J.-E.
more...
Nat. Genet.29:166-173(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6 .
tissue :
Brain .
tissue :
Mammary gland .
5.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 847-1651 (ISOFORM 1)
strain :
C57BL/6J .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic brain .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-477 AND SER-486;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
8.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-527;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .