AMOT ELISA Kit for Human(Homo sapiens) | EIAab.comAMOT ELISA Kit for Human(Homo sapiens)

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Index > Protein center > AMOT(Gene name) > Human

AMOT (Gene name),

Angiomotin (Protein name ), AMOT_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

AMOT(KIAA1071);

Protein name:

Angiomotin;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3. Interacts with MAGI1. Isoform 1 interacts with angiostatin.

Function:

Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Subcellular Location:

Cell junction tight junction Localized on the cell surface. May act as a transmembrane protein.

Protein Attributes:

Sequence length:

1084

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

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650:

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750:

800:

850:

900:

950:

1000:

1050:

1084:

KTDGPVFHSN | TLERKTPIQI | LGQEPDAEMV | EYLI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000361027

KEGG:

hsa:154796

MIM:

300410

UniGene:

Hs.528051

Pfam:

PF12240

String:

Q4VCS5

Uniprot:

Q4VCS5

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ELISA Kit for Human Angiomotin

Cat.:

E2294h

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Manual:

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Packing:

96T

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ELISA Kit for Human Angiomotin

Cat.:

E2294m

Price:

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Human Angiomotin

Cat.:

U2294h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human Angiomotin

Cat.:

U2294m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Angiomotin

Cat.:

P2294Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Angiomotin

Cat.:

P2294Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Angiomotin

Protein for Human Angiomotin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Angiomotin. An angiostatin binding protein that regulates endothelial cell migration and tube formation."
Troyanovsky B. , Levchenko T. , Maensson G. , Matvijenko O. , Holmgren L.
J. Cell Biol.152:1247-1254(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY;FUNCTION
tissue: Placenta.
2.

"Angiomotin regulates endothelial cell-cell junctions and cell motility."
Bratt A. , Birot O. , Sinha I. , Veitonmaeki N. , Aase K. , Ernkvist M. , Holmgren L.
J. Biol. Chem.280:34859-34869(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TOPOLOGY;INTERACTION WITH ANGIOSTATIN AND MAGI1;SUBCELLULAR LOCATION
3.

"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
Kikuno R. , Nagase T. , Ishikawa K. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.6:197-205(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Brain.
4.

"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-543 (ISOFORM 1)
tissue: Spinal cord.
6.

"A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells."
Wells C.D. , Fawcett J.P. , Traweger A. , Yamanaka Y. , Goudreault M. , Elder K. , Kulkarni S. , Gish G. , Virag C. , Lim C. , Colwill K. , Starostine A. , Metalnikov P. , Pawson T.
Cell125:535-548(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;DOMAIN;FUNCTION;IDENTIFICATION IN A COMPLEX WITH ARHGAP17; MPP5; INADL AND PARD3
7.

"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic kidney.
8.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation."
Wang C. , An J. , Zhang P. , Xu C. , Gao K. , Wu D. , Wang D. , Yu H. , Liu J.O. , Yu L.
Biochem. J.444:279-289(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION BY NEDD4; NEDD4L AND ITCH

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