Gene name:
Amot (Kiaa1071) ;
Protein name:
Angiomotin ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3. Interacts with MAGI1 and angiostatin.
Function:
Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Subcellular Location:
Cell junction
tight junction
Localized on the cell surface. May act as a transmembrane protein.
Protein Attributes:
50:
MRSSDDQPSG | GTTVLQRLLQ | EQLRYGNPSE | NRSLLAIHQQ | ATGNSSPFST |
100:
GSGNQGPQND | VLSSQDHHQQ | QLVAHPARQE | PQGQEIQSEN | GVMEKQLSPR |
150:
MQNNEELPTY | EEAKVQSQYF | RGQQHASVGA | AFYVTGVTNQ | KMRTEGRPSV |
200:
QRLTPGKMHQ | DEGLRDLKQG | HVRSLSERLM | QMSLATSGVK | AHPPVTSAPL |
250:
SPPQPNDLYK | NATSSSEFYK | AQGPPPSQHS | LKGMEHRGPP | PEYPFKGVPS |
300:
QSVVCKSQEP | GHFYSEHRLN | QPGRTEGQLM | RYQHPPEYGA | ARATQDISSL |
350:
SLSARNSQPH | SPTSSLTAGA | SSLPLLQSPP | STRLPPGQHL | VSNQGDHSAH |
400:
LSRHQQHLLS | SQSHQGDHYR | HAQASLTSAQ | QQPGEAYSAM | PRAQQSASYQ |
450:
PMPADPFAMV | SRAQQMVEIL | SDENRNLRQE | LDGCYEKVAR | LQKVETEIQR |
500:
VSEAYENLVK | SSSKREALEK | AMRNKLEGEI | RRMHDFNRDL | RDRLETANKQ |
550:
LAEKEYEGSE | DTRKTISQLF | AKHKENQREK | EKLEAELATA | RSTNEDQRRH |
600:
IEIRDQALSN | AQAKVVKLEE | ELKKKQVYVD | KVEKMQQALV | QLQAACEKRE |
650:
QLEHRLRTRL | ERELESLRIQ | QRQGNSQPTN | ASEYNAAALM | ELLREKEERI |
700:
LALEADMTKW | EQKYLEENVM | RHFALDAAAT | VAAQRDTTVI | SHSPNTSYDT |
750:
ALEARIQKEE | EEILMANKRC | LDMEGRIKTL | HAQIIEKDAM | IKVLQQRSRK |
800:
EPSKTEQLSS | MRPAKSLMSI | SNAGSGLLAH | SSTLTGAPIM | EEKRDDKSWK |
850:
GSLGVLLGGD | YRVEPVPSTP | SPVPPSTPLL | SAHSKTGSRD | CSTQTERGPE |
900:
STKTAAVTPI | SAPMAGPVAA | AAPAAAINAT | AATNTATAAT | NTTIMVAAAP |
950:
VAVAAVAAPA | AAAATPSPAN | AAALAAAAAP | ATSVSAATSV | SAANSISPAA |
1000:
PVAPAAVVPP | AAPVSPAAAV | QIPAAASLTP | ATVSPTAATA | TAAVAAATTA |
1050:
AITAAAAAAT | TAIQVAPATS | APVPSPASIP | APATAQASAP | TPTQASTPAP |
1100:
TEPPSPVPTP | TPALVQTEGP | ANPGASSGPR | RLSTPNLMCN | PDKPDAPAFH |
1126:
SSTLERKTPI | QILGQEPDAE | MVEYLI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Angiomotin
ELISA Kit for Mouse Angiomotin
CLIA Kit for Mouse Angiomotin
CLIA Kit for Mouse Angiomotin
Polyclonal Antibody for Mouse Angiomotin
Polyclonal Antibody for Mouse Angiomotin
Monoclonal Antibody for Mouse Angiomotin
Monoclonal Antibody for Mouse Angiomotin
Protein for Mouse Angiomotin
Protein for Mouse Angiomotin
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 183-1126 (ISOFORM 2)
strain :
FVB/N .
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 199-1126 (ISOFORM 1);TISSUE SPECIFICITY
strain :
B6CBAF2 .
tissue :
Placenta .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 588-1126 (ISOFORM 1)
tissue :
Embryonic tail .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-693;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .