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Index > Protein center > AMBRA1(Gene name) > Human
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  • AMBRA1 (Gene name),
  • Activating molecule in BECN1-regulated autophagy protein 1 (Protein name ),  AMRA1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AMBRA1(KIAA1736);
    Protein name:
    Activating molecule in BECN1-regulated autophagy protein 1;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3.
    Function:
    Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
    Subcellular Location:
    Cytoplasmic vesicle autophagosome
    Protein Attributes:
    Sequence length:
    1298
    Sequence:
    50:
    MKVVPEKNAV | RILWGRERGA | RAMGAQRLLQ | ELVEDKTRWM | KWEGKRVELP | 
    100:
    DSPRSTFLLA | FSPDRTLLAS | THVNHNIYIT | EVKTGKCVHS | LIGHRRTPWC | 
    150:
    VTFHPTISGL | IASGCLDGEV | RIWDLHGGSE | SWFTDSNNAI | ASLAFHPTAQ | 
    200:
    LLLIATANEI | HFWDWSRREP | FAVVKTASEM | ERVRLVRFDP | LGHYLLTAIV | 
    250:
    NPSNQQGDDE | PEIPIDGTEL | SHYRQRALLQ | SQPVRRTPLL | HNFLHMLSSR | 
    300:
    SSGIQVGEQS | TVQDSATPSP | PPPPPQPSTE | RPRTSAYIRL | RQRVSYPTAE | 
    350:
    CCQHLGILCL | CSRCSGTRVP | SLLPHQDSVP | PASARATTPS | FSFVQTEPFH | 
    400:
    PPEQASSTQQ | DQGLLNRPSA | FSTVQSSTAG | NTLRNLSLGP | TRRSLGGPLS | 
    450:
    SHPSRYHREI | APGLTGSEWT | RTVLSLNSRS | EAESMPPPRT | SASSVSLLSV | 
    500:
    LRQQEGGSQA | SVYTSATEGR | GFPASGLATE | SDGGNGSSQN | NSGSIRHELQ | 
    550:
    CDLRRFFLEY | DRLQELDQSL | SGEAPQTQQA | QEMLNNNIES | ERPGPSHQPT | 
    600:
    PHSSENNSNL | SRGHLNRCRA | CHNLLTFNND | TLRWERTTPN | YSSGEASSSW | 
    650:
    QVPSSFESVP | SSGSQLPPLE | RTEGQTPSSS | RLELSSSASP | QEERTVGVAF | 
    700:
    NQETGHWERI | YTQSSRSGTV | SQEALHQDMP | EESSEEDSLR | RRLLESSLIS | 
    750:
    LSRYDGAGSR | EHPIYPDPAR | LSPAAYYAQR | MIQYLSRRDS | IRQRSMRYQQ | 
    800:
    NRLRSSTSSS | SSDNQGPSVE | GTDLEFEDFE | DNGDRSRHRA | PRNARMSAPS | 
    850:
    LGRFVPRRFL | LPEYLPYAGI | FHERGQPGLA | THSSVNRVLA | GAVIGDGQSA | 
    900:
    VASNIANTTY | RLQWWDFTKF | DLPEISNASV | NVLVQNCKIY | NDASCDISAD | 
    950:
    GQLLAAFIPS | SQRGFPDEGI | LAVYSLAPHN | LGEMLYTKRF | GPNAISVSLS | 
    1000:
    PMGRYVMVGL | ASRRILLHPS | TEHMVAQVFR | LQQAHGGETS | MRRVFNVLYP | 
    1050:
    MPADQRRHVS | INSARWLPEP | GLGLAYGTNK | GDLVICRPEA | LNSGVEYYWD | 
    1100:
    QLNETVFTVH | SNSRSSERPG | TSRATWRTDR | DMGLMNAIGL | QPRNPATSVT | 
    1150:
    SQGTQTLALQ | LQNAETQTER | EVPEPGTAAS | GPGEGEGSEY | GASGEDALSR | 
    1200:
    IQRLMAEGGM | TAVVQREQST | TMASMGGFGN | NIIVSHRIHR | SSQTGTEPGA | 
    1250:
    AHTSSPQPST | SRGLLPEAGQ | LAERGLSPRT | ASWDQPGTPG | REPTQPTLPS | 
    1298:
    SSPVPIPVSL | PSAEGPTLHC | ELTNNNHLLD | GGSSRGDAAG | PRGEPRNR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    Pfam:
    KEGG:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Activating molecule in BECN1-regulated autophagy protein 1
    ELISA Kit for Human Activating molecule in BECN1-regulated autophagy protein 1
    CLIA Kit for Human Activating molecule in BECN1-regulated autophagy protein 1
    CLIA Kit for Human Activating molecule in BECN1-regulated autophagy protein 1
    Polyclonal Antibody for Human Activating molecule in BECN1-regulated autophagy protein 1
    Polyclonal Antibody for Human Activating molecule in BECN1-regulated autophagy protein 1
    Monoclonal Antibody for Human Activating molecule in BECN1-regulated autophagy protein 1
    Monoclonal Antibody for Human Activating molecule in BECN1-regulated autophagy protein 1
    Protein for Human Activating molecule in BECN1-regulated autophagy protein 1
    Protein for Human Activating molecule in BECN1-regulated autophagy protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: Brain.
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Kikuno R. , Hattori A. , Kondo Y. , Okumura K. , Ohara O.
      DNA Res.7:347-355(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 464-1298
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6)
      tissue: Melanoma.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Testis.
    8. 8.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-639;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-639;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-639;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism."
      He C. , Wei Y. , Sun K. , Li B. , Dong X. , Zou Z. , Liu Y. , Kinch L.N. , Khan S. , Sinha S. , Xavier R.J. , Grishin N.V. , Xiao G. , Eskelinen E.L. , Scherer P.E. , Whistler J.L. , Levine B.
      Cell154:1085-1099(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BECN1P1/BECN2
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