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Index > Protein center > AMY2A(Gene name) > Human
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  • AMY2A (Gene name),
  • Pancreatic alpha-amylase (Protein name ),  AMYP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AMY2A;
    Protein name:
    Pancreatic alpha-amylase(PA);
    Alternative:
    1,4-alpha-D-glucan glucanohydrolase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Subcellular Location:
    Secreted extracellular space
    Protein Attributes:
    Sequence length:
    511
    Sequence:
    50:
    MKFFLLLFTI | GFCWAQYSPN | TQQGRTSIVH | LFEWRWVDIA | LECERYLAPK | 
    100:
    GFGGVQVSPP | NENVAIYNPF | RPWWERYQPV | SYKLCTRSGN | EDEFRNMVTR | 
    150:
    CNNVGVRIYV | DAVINHMCGN | AVSAGTSSTC | GSYFNPGSRD | FPAVPYSGWD | 
    200:
    FNDGKCKTGS | GDIENYNDAT | QVRDCRLTGL | LDLALEKDYV | RSKIAEYMNH | 
    250:
    LIDIGVAGFR | LDASKHMWPG | DIKAILDKLH | NLNSNWFPAG | SKPFIYQEVI | 
    300:
    DLGGEPIKSS | DYFGNGRVTE | FKYGAKLGTV | IRKWNGEKMS | YLKNWGEGWG | 
    350:
    FVPSDRALVF | VDNHDNQRGH | GAGGASILTF | WDARLYKMAV | GFMLAHPYGF | 
    400:
    TRVMSSYRWP | RQFQNGNDVN | DWVGPPNNNG | VIKEVTINPD | TTCGNDWVCE | 
    450:
    HRWRQIRNMV | IFRNVVDGQP | FTNWYDNGSN | QVAFGRGNRG | FIVFNNDDWS | 
    500:
    FSLTLQTGLP | AGTYCDVISG | DKINGNCTGI | KIYVSDDGKA | HFSISNSAED | 
    511:
    PFIAIHAESK | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    MIM:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human PA
    Cat.:
    E2171h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PA
    Cat.:
    U2171h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human PA
    Cat.:
    P2171Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PA
    Protein for Human PA

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Corrected sequences of cDNAs for human salivary and pancreatic alpha-amylases."
      Nakamura Y. , Ogawa M. , Nishide T. , Emi M. , Kosaki G. , Himeno S. , Matsubara K.
      Gene28:263-270(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;SEQUENCE REVISION
    3. 3.
      "Primary structure of human pancreatic alpha-amylase gene: its comparison with human salivary alpha-amylase gene."
      Horii A. , Emi M. , Tomita N. , Nishide T. , Ogawa M. , Mori T. , Matsubara K.
      Gene60:57-64(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Pancreas.
    4. 4.
      "A complementary DNA sequence that predicts a human pancreatic amylase primary structure consistent with the electrophoretic mobility of the common isozyme, Amy2 A."
      Wise R.J. , Karn R.C. , Larsen S.H. , Hodes M.E. , Gardell S.J. , Rutter W.J.
      Mol. Biol. Med.2:307-322(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Pancreas.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Pancreas.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-56
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-56
    8. 8.
      "The active center of a mammalian alpha-amylase. Structure of the complex of a pancreatic alpha-amylase with a carbohydrate inhibitor refined to 2.2-A resolution."
      Qian M. , Haser R. , Buisson G. , Duee E. , Payan F.
      Biochemistry33:6284-6294(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
    9. 9.
      "The structure of human pancreatic alpha-amylase at 1.8-A resolution and comparisons with related enzymes."
      Brayer G.D. , Luo Y. , Withers S.G.
      Protein Sci.4:1730-1742(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS);PYROGLUTAMATE FORMATION AT GLU-16
    10. 10.
      "Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris."
      Rydberg E.H. , Sidhu G. , Vo H.C. , Hewitt J. , Cote H.C.F. , Wang Y. , Numao S. , MacGillivray R.T.A. , Overall C.M. , Brayer G.D. , Withers S.G.
      Protein Sci.8:635-643(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS);MUTAGENESIS OF ASP-212
    11. 11.
      "Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques."
      Brayer G.D. , Sidhu G. , Maurus R. , Rydberg E.H. , Braun C. , Wang Y. , Nguyen N.T. , Overall C.M. , Withers S.G.
      Biochemistry39:4778-4791(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)
    12. 12.
      "Probing the role of the chloride ion in the mechanism of human pancreatic alpha-amylase."
      Numao S. , Maurus R. , Sidhu G. , Wang Y. , Overall C.M. , Brayer G.D. , Withers S.G.
      Biochemistry41:215-225(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS);MUTAGENESIS OF ARG-210; ASN-313 AND ARG-352
    13. 13.
      "Mechanistic analyses of catalysis in human pancreatic alpha-amylase: detailed kinetic and structural studies of mutants of three conserved carboxylic acids."
      Rydberg E.H. , Li C. , Maurus R. , Overall C.M. , Brayer G.D. , Withers S.G.
      Biochemistry41:4492-4502(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS);MUTAGENESIS OF ASP-212; GLU-248 AND ASP-315
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