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Index > Protein center > ANGPTL2(Gene name) > Human
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  • ANGPTL2 (Gene name),
  • Angiopoietin-related protein 2 (Protein name ),  ANGL2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (1)
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    • Gene name:
    ANGPTL2(UNQ170/PRO196;ARP2);
    Protein name:
    Angiopoietin-related protein 2;
    Alternative:
    Angiopoietin-like protein 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Induces sprouting in endothelial cells through an autocrine and paracrine action.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    493
    Sequence:
    50:
    MRPLCVTCWW | LGLLAAMGAV | AGQEDGFEGT | EEGSPREFIY | LNRYKRAGES | 
    100:
    QDKCTYTFIV | PQQRVTGAIC | VNSKEPEVLL | ENRVHKQELE | LLNNELLKQK | 
    150:
    RQIETLQQLV | EVDGGIVSEV | KLLRKESRNM | NSRVTQLYMQ | LLHEIIRKRD | 
    200:
    NALELSQLEN | RILNQTADML | QLASKYKDLE | HKYQHLATLA | HNQSEIIAQL | 
    250:
    EEHCQRVPSA | RPVPQPPPAA | PPRVYQPPTY | NRIINQISTN | EIQSDQNLKV | 
    300:
    LPPPLPTMPT | LTSLPSSTDK | PSGPWRDCLQ | ALEDGHDTSS | IYLVKPENTN | 
    350:
    RLMQVWCDQR | HDPGGWTVIQ | RRLDGSVNFF | RNWETYKQGF | GNIDGEYWLG | 
    400:
    LENIYWLTNQ | GNYKLLVTME | DWSGRKVFAE | YASFRLEPES | EYYKLRLGRY | 
    450:
    HGNAGDSFTW | HNGKQFTTLD | RDHDVYTGNC | AHYQKGGWWY | NACAHSNLNG | 
    493:
    VWYRGGHYRS | RYQDGVYWAE | FRGGSYSLKK | VVMMIRPNPN | TFH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Hs.653262
    MIM:
    605001
    String:
    Q9UKU9
    Pfam:
    PF00147
    STRING:
    9606.ENSP00000362524
    SMR:
    Q9UKU9
    KEGG:
    hsa:23452
    Uniprot:
    Q9UKU9
     
    FOR
    ELISA Kit for Human Angiopoietin-related protein 2
    Cat.:
    E1919m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Angiopoietin-related protein 2
    Cat.:
    E1919h
    Price:
    Please sign in first.
    Manual:
    Looking for manual.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Angiopoietin-related protein 2
    Cat.:
    U1919m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Angiopoietin-related protein 2
    Cat.:
    U1919h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Angiopoietin-related protein 2
    Cat.:
    P1919Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Angiopoietin-related protein 2
    Cat.:
    P1919Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Angiopoietin-related protein 2
    Monoclonal Antibody for Human Angiopoietin-related protein 2
    Protein for Human Angiopoietin-related protein 2
    Protein for Human Angiopoietin-related protein 2

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

            12% SDS-PAGE Analysis

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 4.4%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 8.4%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    87

    86-92

    Plasma

    88

    87-92

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1：2

    1:4

    1:8

    1:16

    serum(n=5)

    86-96%

    88-97%

    91-103%

    89-99%

    EDTA plasma(n=5)

    87-95%

    90-98%

    89-101%

    90-98%

    heparin plasma(n=5)

    90-97%

     

    89-96%

    94-105%

    91-107%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Citations
    [1].
    "Serum Angptl2 levels are independently associated with albuminuria in type 2 diabetes"
    Qin Li, Wei Gong, Zhihong Yang, et al.
    From:Diabetes Research and Clinical Practice
    References
    1. 1.
      "Molecular cloning, expression, and characterization of angiopoietin-related protein. angiopoietin-related protein induces endothelial cell sprouting."
      Kim I. , Moon S.-O. , Koh K.N. , Kim H. , Uhm C.-S. , Kwak H.J. , Kim N.-G. , Koh G.Y.
      J. Biol. Chem.274:26523-26528(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Heart.
    2. 2.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Ovary.
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