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Index > Protein center > ANO6(Gene name) > Human
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  • ANO6 (Gene name),
  • Anoctamin-6 (Protein name ),  ANO6_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ANO6(TMEM16F);
    Protein name:
    Anoctamin-6;
    Alternative:
    Transmembrane protein 16F;Transmembrane protein 16F(SCAN channel);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May act as a calcium-activated chloride channel. It is essential for calcium-dependent exposure of phosphatidylserine on the surface of activated platelets, a process necessary to trigger the clotting system.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    910
    Sequence:
    50:
    MKKMSRNVLL | QMEEEEDDDD | GDIVLENLGQ | TIVPDLGSLE | SQHDFRTPEF | 
    100:
    EEFNGKPDSL | FFNDGQRRID | FVLVYEDESR | KETNKKGTNE | KQRRKRQAYE | 
    150:
    SNLICHGLQL | EATRSVLDDK | LVFVKVHAPW | EVLCTYAEIM | HIKLPLKPND | 
    200:
    LKNRSSAFGT | LNWFTKVLSV | DESIIKPEQE | FFTAPFEKNR | MNDFYIVDRD | 
    250:
    AFFNPATRSR | IVYFILSRVK | YQVINNVSKF | GINRLVNSGI | YKAAFPLHDC | 
    300:
    KFRRQSEDPS | CPNERYLLYR | EWAHPRSIYK | KQPLDLIRKY | YGEKIGIYFA | 
    350:
    WLGYYTQMLL | LAAVVGVACF | LYGYLNQDNC | TWSKEVCHPD | IGGKIIMCPQ | 
    400:
    CDRLCPFWKL | NITCESSKKL | CIFDSFGTLV | FAVFMGVWVT | LFLEFWKRRQ | 
    450:
    AELEYEWDTV | ELQQEEQARP | EYEARCTHVV | INEITQEEER | IPFTAWGKCI | 
    500:
    RITLCASAVF | FWILLIIASV | IGIIVYRLSV | FIVFSAKLPK | NINGTDPIQK | 
    550:
    YLTPQTATSI | TASIISFIII | MILNTIYEKV | AIMITNFELP | RTQTDYENSL | 
    600:
    TMKMFLFQFV | NYYSSCFYIA | FFKGKFVGYP | GDPVYWLGKY | RNEECDPGGC | 
    650:
    LLELTTQLTI | IMGGKAIWNN | IQEVLLPWIM | NLIGRFHRVS | GSEKITPRWE | 
    700:
    QDYHLQPMGK | LGLFYEYLEM | IIQFGFVTLF | VASFPLAPLL | ALVNNILEIR | 
    750:
    VDAWKLTTQF | RRLVPEKAQD | IGAWQPIMQG | IAILAVVTNA | MIIAFTSDMI | 
    800:
    PRLVYYWSFS | VPPYGDHTSY | TMEGYINNTL | SIFKVADFKN | KSKGNPYSDL | 
    850:
    GNHTTCRYRD | FRYPPGHPQE | YKHNIYYWHV | IAAKLAFIIV | MEHVIYSVKF | 
    900:
    FISYAIPDVS | KRTKSKIQRE | KYLTQKLLHE | NHLKDMTKNM | GVIAERMIEA | 
    910:
    VDNNLRPKSE | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Anoctamin-6
    ELISA Kit for Human Anoctamin-6
    CLIA Kit for Human Anoctamin-6
    CLIA Kit for Human Anoctamin-6
    Polyclonal Antibody for Human Anoctamin-6
    Polyclonal Antibody for Human Anoctamin-6
    Monoclonal Antibody for Human Anoctamin-6
    Monoclonal Antibody for Human Anoctamin-6
    Protein for Human Anoctamin-6
    Protein for Human Anoctamin-6

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Placenta.
      tissue: Testis.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 772-910 (ISOFORM 1/2)
      tissue: Adipose tissue.
    4. 4.
      "Identification and characterization of TMEM16E and TMEM16F genes in silico."
      Katoh M. , Katoh M.
      Int. J. Oncol.24:1345-1349(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    5. 5.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-493
      tissue: Liver.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
    7. 7.
      "Calcium-dependent phospholipid scrambling by TMEM16F."
      Suzuki J. , Umeda M. , Sims P.J. , Nagata S.
      Nature468:834-838(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INVOLVEMENT IN SCOTT SYNDROME
    8. 8.
      "Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?"
      Duran C. , Hartzell H.C.
      Acta Pharmacol. Sin.32:685-692(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    10. 10.
      "Anoctamin 6 is an essential component of the outwardly rectifying chloride channel."
      Martins J.R. , Faria D. , Kongsuphol P. , Reisch B. , Schreiber R. , Kunzelmann K.
      Proc. Natl. Acad. Sci. U.S.A.108:18168-18172(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    11. 11.
      "ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins."
      Duran C. , Qu Z. , Osunkoya A.O. , Cui Y. , Hartzell H.C.
      Am. J. Physiol.302:C482-C493(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    12. 12.
      "The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age."
      Winpenny J.P. , Gray M.A.
      Exp. Physiol.97:175-176(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    13. 13.
      "The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels."
      Scudieri P. , Sondo E. , Ferrera L. , Galietta L.J.
      Exp. Physiol.97:177-183(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW;ABSENCE OF CALCIUM-ACTIVATED CHLORIDE CHANNEL ACTIVITY
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW;FUNCTION
    15. 15.
      "Anoctamins are a family of Ca2+ activated Cl- channels."
      Tian Y. , Schreiber R. , Kunzelmann K.
      J. Cell Sci.125:4991-4998(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
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