Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > NPR1(Gene name) > Human
  • Add your favorite
  • NPR1 (Gene name),
  • Atrial natriuretic peptide receptor 1 (Protein name ),  ANPRA_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    NPR1(ANPRA);
    Protein name:
    Atrial natriuretic peptide receptor 1;
    Alternative:
    Guanylate cyclase A(GC-A);Atrial natriuretic peptide receptor type A(ANP-A;ANPR-A;NPR-A);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1061
    Sequence:
    50:
    MPGPRRPAGS | RLRLLLLLLL | PPLLLLLRGS | HAGNLTVAVV | LPLANTSYPW | 
    100:
    SWARVGPAVE | LALAQVKARP | DLLPGWTVRT | VLGSSENALG | VCSDTAAPLA | 
    150:
    AVDLKWEHNP | AVFLGPGCVY | AAAPVGRFTA | HWRVPLLTAG | APALGFGVKD | 
    200:
    EYALTTRAGP | SYAKLGDFVA | ALHRRLGWER | QALMLYAYRP | GDEEHCFFLV | 
    250:
    EGLFMRVRDR | LNITVDHLEF | AEDDLSHYTR | LLRTMPRKGR | VIYICSSPDA | 
    300:
    FRTLMLLALE | AGLCGEDYVF | FHLDIFGQSL | QGGQGPAPRR | PWERGDGQDV | 
    350:
    SARQAFQAAK | IITYKDPDNP | EYLEFLKQLK | HLAYEQFNFT | MEDGLVNTIP | 
    400:
    ASFHDGLLLY | IQAVTETLAH | GGTVTDGENI | TQRMWNRSFQ | GVTGYLKIDS | 
    450:
    SGDRETDFSL | WDMDPENGAF | RVVLNYNGTS | QELVAVSGRK | LNWPLGYPPP | 
    500:
    DIPKCGFDNE | DPACNQDHLS | TLEVLALVGS | LSLLGILIVS | FFIYRKMQLE | 
    550:
    KELASELWRV | RWEDVEPSSL | ERHLRSAGSR | LTLSGRGSNY | GSLLTTEGQF | 
    600:
    QVFAKTAYYK | GNLVAVKRVN | RKRIELTRKV | LFELKHMRDV | QNEHLTRFVG | 
    650:
    ACTDPPNICI | LTEYCPRGSL | QDILENESIT | LDWMFRYSLT | NDIVKGMLFL | 
    700:
    HNGAICSHGN | LKSSNCVVDG | RFVLKITDYG | LESFRDLDPE | QGHTVYAKKL | 
    750:
    WTAPELLRMA | SPPVRGSQAG | DVYSFGIILQ | EIALRSGVFH | VEGLDLSPKE | 
    800:
    IIERVTRGEQ | PPFRPSLALQ | SHLEELGLLM | QRCWAEDPQE | RPPFQQIRLT | 
    850:
    LRKFNRENSS | NILDNLLSRM | EQYANNLEEL | VEERTQAYLE | EKRKAEALLY | 
    900:
    QILPHSVAEQ | LKRGETVQAE | AFDSVTIYFS | DIVGFTALSA | ESTPMQVVTL | 
    950:
    LNDLYTCFDA | VIDNFDVYKV | ETIGDAYMVV | SGLPVRNGRL | HACEVARMAL | 
    1000:
    ALLDAVRSFR | IRHRPQEQLR | LRIGIHTGPV | CAGVVGLKMP | RYCLFGDTVN | 
    1050:
    TASRMESNGE | ALKIHLSSET | KAVLEEFGGF | ELELRGDVEM | KGKGKVRTYW | 
    1061:
    LLGERGSSTR | G
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    Pfam:
    KEGG:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Atrial natriuretic peptide receptor 1
    Cat.:
    E2129r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Atrial natriuretic peptide receptor 1
    Cat.:
    E2129h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Atrial natriuretic peptide receptor 1
    Cat.:
    E2129m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Atrial natriuretic peptide receptor 1
    Cat.:
    U2129r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Atrial natriuretic peptide receptor 1
    Cat.:
    U2129h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Atrial natriuretic peptide receptor 1
    Cat.:
    U2129m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Atrial natriuretic peptide receptor 1
    Cat.:
    P2129Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Atrial natriuretic peptide receptor 1
    Cat.:
    P2129Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Atrial natriuretic peptide receptor 1
    Cat.:
    P2129Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Atrial natriuretic peptide receptor 1
    Monoclonal Antibody for Human Atrial natriuretic peptide receptor 1
    Monoclonal Antibody for Human Atrial natriuretic peptide receptor 1
    Protein for Human Atrial natriuretic peptide receptor 1
    Protein for Human Atrial natriuretic peptide receptor 1
    Protein for Human Atrial natriuretic peptide receptor 1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction."
      Lowe D.G. , Chang M.S. , Hellmiss R. , Chen E. , Singh S. , Garbers D.L. , Goeddel D.V.
      EMBO J.8:1377-1384(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Kidney.
    2. 2.
      "Organization of the human natriuretic peptide receptor A gene."
      Takahashi Y. , Nakayama T. , Soma M. , Izumi Y. , Kanmatsuse K.
      Biochem. Biophys. Res. Commun.246:736-739(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Blood.
    3. 3.
      "Identification of functional polymorphisms in noncoding regions of the human natriuretic peptide receptor A gene."
      Maeda N. , Knowles J.W.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2007-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Placenta.
    8. 8.
      "Expression of mRNA for atrial natriuretic peptide receptor guanylate cyclase (ANPRA) in human retina."
      Pardhasaradhi K. , Kutty R.K. , Gentleman S. , Krishna G.
      Cell. Mol. Neurobiol.14:1-7(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 634-1048
      tissue: Retina.
    9. 9.
      "Extracellular domain-IgG fusion proteins for three human natriuretic peptide receptors. Hormone pharmacology and application to solid phase screening of synthetic peptide antisera."
      Bennett B.D. , Bennett G.L. , Vitangcol R.V. , Jewett J.R. , Burnier J. , Henzel W. , Lowe D.G.
      J. Biol. Chem.266:23060-23067(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIGAND-BINDING
    10. 10.
      "Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP)."
      Koller K.J. , Lowe D.G. , Bennett G.L. , Minamino N. , Kangawa K. , Matsuo H. , Goeddel D.V.
      Science252:120-123(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    11. 11.
      "Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B."
      Yoder A.R. , Stone M.D. , Griffin T.J. , Potter L.R.
      Biochemistry49:10137-10145(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-519; SER-529; THR-532; SER-534 AND SER-538
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a KSR2 Gdf5
    Top Searches
    Ubiquitin-protein ligase Ubiquitin ELISA metalloproteinase Tumor necrosis Asprosin TRAP1A Alpha
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    Twitter