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Index > Protein center > Npr1(Gene name) > Mouse
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  • Npr1 (Gene name),
  • Atrial natriuretic peptide receptor 1 (Protein name ),  ANPRA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Npr1(Npra);
    Protein name:
    Atrial natriuretic peptide receptor 1;
    Alternative:
    Guanylate cyclase A(GC-A);Atrial natriuretic peptide receptor type A(ANP-A;ANPR-A;NPR-A);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1057
    Sequence:
    50:
    MPGSRRVRPR | LRALLLLPPL | LLLRSGHASD | LTVAVVLPLT | NTSYPWSWAR | 
    100:
    VGPAVELALG | RVKARPDLLP | GWTVRMVLGS | SENAAGVCSD | TAAPLAAVDL | 
    150:
    KWEHSPAVFL | GPGCVYSAAP | VGRFTAHWRV | PLLTAGAPAL | GIGVKDEYAL | 
    200:
    TTRTGPSHVK | LGDFVTALHR | RLGWEHQALV | LYADRLGDDR | PCFFIVEGLY | 
    250:
    MRVRERLNIT | VNHQEFVEGD | PDHYTKLLRT | VQRKGRVIYI | CSSPDAFRNL | 
    300:
    MLLALDAGLT | GEDYVFFHLD | VFGQSLQGAQ | GPVPRKPWER | DDGQDRRARQ | 
    350:
    AFQAAKIITY | KEPDNPEYLE | FLKQLKLLAD | KKFNFTMEDG | LKNIIPASFH | 
    400:
    DGLLLYVQAV | TETLAQGGTV | TDGENITQRM | WNRSFQGVTG | YLKIDRNGDR | 
    450:
    DTDFSLWDMD | PETGAFRVVL | NFNGTSQELM | AVSEHRLYWP | LGYPPPDIPK | 
    500:
    CGFDNEDPAC | NQDHFSTLEV | LALVGSLSLV | SFLIVSFFIY | RKMQLEKELV | 
    550:
    SELWRVRWED | LQPSSLERHL | RSAGSRLTLS | GRGSNYGSLL | TTEGQFQVFA | 
    600:
    KTAYYKGNLV | AVKRVNRKRI | ELTRKVLFEL | KHMRDVQNEH | LTRFVGACTD | 
    650:
    PPNICILTEY | CPRGSLQDIL | ENESITLDWM | FRYSLTNDIV | KGMLFLHNGA | 
    700:
    IGSHGNLKSS | NCVVDGRFVL | KITDYGLESF | RDPEPEQGHT | LFAKKLWTAP | 
    750:
    ELLRMASPPA | RGSQAGDVYS | FGIILQEIAL | RSGVFYVEGL | DLSPKEIIER | 
    800:
    VTRGEQPPFR | PSMDLQSHLE | ELGQLMQRCW | AEDPQERPPF | QQIRLALRKF | 
    850:
    NKENSSNILD | NLLSRMEQYA | NNLEELVEER | TQAYLEEKRK | AEALLYQILP | 
    900:
    HSVAEQLKRG | ETVQAEAFDS | VTIYFSDIVG | FTALSAESTP | MQVVTLLNDL | 
    950:
    YTCFDAVIDN | FDVYKVETIG | DAYMVVSGLP | VRNGQLHARE | VARMALALLD | 
    1000:
    AVRSFRIRHR | PQEQLRLRIG | IHTGPVCAGV | VGLKMPRYCL | FGDTVNTASR | 
    1050:
    MESNGEALRI | HLSSETKAVL | EEFDGFELEL | RGDVEMKGKG | KVRTYWLLGE | 
    1057:
    RGCSTRG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    E2129r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    E2129h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    E2129m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    U2129r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    U2129h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    U2129m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    P2129Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    P2129Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 1
    Cat.:
    P2129Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 1
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 1
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 1
    Protein for Mouse Atrial natriuretic peptide receptor 1
    Protein for Mouse Atrial natriuretic peptide receptor 1
    Protein for Mouse Atrial natriuretic peptide receptor 1

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning and expression of murine guanylate cyclase/atrial natriuretic factor receptor cDNA."
      Pandey K.N. , Singh S.
      J. Biol. Chem.265:12342-12348(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6J.
    2. 2.
      "Agonist selectivity for three species of natriuretic peptide receptor-A."
      Schoenfeld J.R. , Sehl P. , Quan C. , Burnier J.P. , Lowe D.G.
      Mol. Pharmacol.47:172-180(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A."
      Oliver P.M. , Fox J.E. , Kim R. , Rockman H.A. , Kim H.S. , Reddick R.L. , Pandey K.N. , Milgram S.L. , Smithies O. , Maeda N.
      Proc. Natl. Acad. Sci. U.S.A.94:14730-14735(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
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