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Index > Protein center > Npr3(Gene name) > Mouse
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  • Npr3 (Gene name),
  • Atrial natriuretic peptide receptor 3 (Protein name ),  ANPRC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Npr3;
    Protein name:
    Atrial natriuretic peptide receptor 3;
    Alternative:
    Atrial natriuretic peptide receptor type C(ANP-C;ANPR-C;NPR-C);Atrial natriuretic peptide clearance receptor;EF-2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    536
    Sequence:
    50:
    MRSFLLFTFS | ACVLLARVLL | AGGASSGAGD | TRPGSRRRAR | EALAAQKIEV | 
    100:
    LVLLPRDDSY | LFSLARVRPA | IEYALRSVEG | NGTGRKLLPP | GTRFQVAYED | 
    150:
    SDCGNRALFS | LVDRVAAARG | AKPDLILGPV | CEYAAAPVAR | LASHWDLPML | 
    200:
    SAGALAAGFQ | HKDTEYSHLT | RVAPAYAKMG | EMMLALFRHH | HWSRAALVYS | 
    250:
    DDKLERNCYF | TLEGVHEVFQ | EEGLHTSAYN | FDETKDLDLD | DIVRYIQGSE | 
    300:
    RVVIMCASGD | TIRRIMLAVH | RHGMTSGDYA | FFNIELFNSS | SYGDGSWRRG | 
    350:
    DKHDSEAKQA | YSSLQTVTLL | RTVKPEFEKF | SMEVKSSVEK | QGLNEEDYVN | 
    400:
    MFVEGFHDAI | LLYVLALHEV | LRAGYSKKDG | GKIIQQTWNR | TFEGIAGQVS | 
    450:
    IDANGDRYGD | FSVVAMTDTE | AGTQEVIGDY | FGKEGRFQMR | SNVKYPWGPL | 
    500:
    KLRLDETRIV | EHTNSSPCKS | SGGLEESAVT | GIVVGALLGA | GLLMAFYFFR | 
    536:
    KKYRITIERR | NQQEESNIGK | HRELREDSIR | SHFSVA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    E9980h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    E9980b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    E9980r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    E9980m
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    U9980m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    U9980h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    U9980b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    U9980r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    P9980Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    P9980Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Polyclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Cat.:
    P9980Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Monoclonal Antibody for Mouse Atrial natriuretic peptide receptor 3
    Protein for Mouse Atrial natriuretic peptide receptor 3
    Protein for Mouse Atrial natriuretic peptide receptor 3
    Protein for Mouse Atrial natriuretic peptide receptor 3
    Protein for Mouse Atrial natriuretic peptide receptor 3

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    References
    1. 1.
      "Structure of the 5'-flanking regulatory region of the mouse gene encoding the clearance receptor for atrial natriuretic peptide."
      Yanaka N. , Kotera J. , Taguchi I. , Sugiura M. , Kawashima K. , Omori K.
      Eur. J. Biochem.237:25-34(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Lung.
    2. 2.
      "Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3)."
      Jaubert J. , Jaubert F. , Martin N. , Washburn L.L. , Lee B.K. , Eicher E.M. , Guenet J.-L.
      Proc. Natl. Acad. Sci. U.S.A.96:10278-10283(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LGJ ASN-168;VARIANT LGJ-2J 66-ARG--SER-77 DEL
      strain: 129/Sv.
      strain: BALB/c.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts."
      Fu X. , Kamps M.P.
      Mol. Cell. Biol.17:1503-1512(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 255-439
    6. 6.
      "The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system."
      Matsukawa N. , Grzesik W.J. , Takahashi N. , Pandey K.N. , Pang S. , Yamauchi M. , Smithies O.
      Proc. Natl. Acad. Sci. U.S.A.96:7403-7408(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
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