SERPINC1 ELISA Kit for Human(Homo sapiens) | EIAab.comSERPINC1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SERPINC1(Gene name) > Human

SERPINC1 (Gene name),

Antithrombin-III (Protein name ), ANT3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SERPINC1(PRO0309;AT3);

Protein name:

Antithrombin-III(ATIII);

Alternative:

Serpin C1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.

Subcellular Location:

Secreted extracellular space

Protein Attributes:

Sequence length:

464

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

464:

TIIFMGRVAN | PCVK

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

MIM:

107300

String:

P01008

UniGene:

Hs.75599

Pfam:

PF00079

SMR:

P01008

KEGG:

hsa:462

Uniprot:

P01008

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ELISA Kit for Human ATIII

Cat.:

E0878b

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Packing:

96T

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ELISA Kit for Human ATIII

Cat.:

E0878c

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96T

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ELISA Kit for Human ATIII

Cat.:

E0878h

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96T

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ELISA Kit for Human ATIII

Cat.:

E0878m

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Packing:

96T

CLIA Kit for Human ATIII

Cat.:

U0878h

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96T

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CLIA Kit for Human ATIII

MSDS:

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CLIA Kit for Human ATIII

Cat.:

U0878b

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Packing:

96T

CLIA Kit for Human ATIII

Cat.:

U0878m

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96T

Polyclonal Antibody for Human ATIII

Cat.:

P0878Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ATIII

Cat.:

P0878Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human ATIII

Monoclonal Antibody for Human ATIII

Protein for Human ATIII

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and expression of the cDNA for human antithrombin III."
Bock S.C. , Wion K.L. , Vehar G.A. , Lawn R.M.
Nucleic Acids Res.10:8113-8125(1982) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Isolation and sequence characterization of a cDNA clone of human antithrombin III."
Chandra T. , Stackhouse R. , Kidd V.J. , Woo S.L.C.
Proc. Natl. Acad. Sci. U.S.A.80:1845-1848(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Hereditary antithrombin III deficiency: identification of an arginine-406 to methionine point mutation near protease reactive site."
Tsuji H. , Takada O. , Nakagawa M. , Tanaka S. , Hashimoto-Gotoh T.

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT AT3D MET-438
4.

"Complete nucleotide sequence of the antithrombin gene: evidence for homologous recombination causing thrombophilia."
Olds R.J. , Lane D.A. , Chowdhury V. , de Stefano V. , Leone G. , Thein S.L.
Biochemistry32:4216-4224(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Functional prediction of the coding sequences of 75 new genes deduced by analysis of cDNA clones from human fetal liver."
Zhang C. , Yu Y. , Zhang S. , Wei H. , Bi J. , Zhou G. , Dong C. , Zai Y. , Xu W. , Gao F. , Liu M. , He F.
Submitted (1999-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Fetal liver.
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
7.

SeattleSNPs variation discovery resource
Submitted (2001-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLU-30 AND ALA-147
8.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
10.

"Primary structure of antithrombin-III (heparin cofactor). Partial homology between alpha-1-antitrypsin and antithrombin-III."
Petersen T.E. , Dudek-Wojciechowska G. , Sottrup-Jensen L. , Magnusson S.

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 33-464;GLYCOSYLATION AT ASN-128; ASN-167; ASN-187 AND ASN-224;DISULFIDE BONDS
11.

"Isolation of a cDNA clone for human antithrombin III."
Prochownik E.V. , Markham A.F. , Orkin S.H.
J. Biol. Chem.258:8389-8394(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 42-464
12.

"Antithrombin III Utah: proline-407 to leucine mutation in a highly conserved region near the inhibitor reactive site."
Bock S.C. , Marrinan J.A. , Radziejewska E.
Biochemistry27:6171-6178(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 137-208;VARIANT AT3D LEU-439
13.

"Antithrombin-TRI (Ala382 to Thr) causing severe thromboembolic tendency undergoes the S-to-R transition and is associated with a plasma-inactive high-molecular-weight complex of aggregated antithrombin."
Lindo V.S. , Kakkar V.V. , Learmonth M. , Melissari E. , Zappacosta F. , Panico M. , Morris H.R.
Br. J. Haematol.89:589-601(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 371-425;MASS SPECTROMETRY;VARIANT AT3D THR-414
tissue: Plasma.
14.

"The site in human antithrombin for functional proteolytic cleavage by human thrombin."
Bjoerk I. , Danielsson A. , Fenton J.W. II , Joernvall H.
FEBS Lett.126:257-260(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REACTIVE SITE
15.

"The heparin-binding site of antithrombin III. Identification of a critical tryptophan in the amino acid sequence."
Blackburn M.N. , Smith R.L. , Carson J. , Sibley C.C.
J. Biol. Chem.259:939-941(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: HEPARIN-BINDING SITE
16.

"A proteomic analysis of human bile."
Kristiansen T.Z. , Bunkenborg J. , Gronborg M. , Molina H. , Thuluvath P.J. , Argani P. , Goggins M.G. , Maitra A. , Pandey A.
Mol. Cell. Proteomics3:715-728(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-187
tissue: Bile.
17.

"Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
Bunkenborg J. , Pilch B.J. , Podtelejnikov A.V. , Wisniewski J.R.
Proteomics4:454-465(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-128 AND ASN-187
tissue: Plasma.
18.

"Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity."
Szabo R. , Netzel-Arnett S. , Hobson J.P. , Antalis T.M. , Bugge T.H.
Biochem. J.390:231-242(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MEMBRANE-ANCHORED SERINE PROTEASE TMPRSS7 INHIBITION;HETERODIMER WITH TMPRSS7
19.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-128; ASN-187 AND ASN-224
tissue: Plasma.
20.

"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-224
tissue: Platelet.
21.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-128 AND ASN-187
tissue: Liver.
22.

"Enrichment of glycopeptides for glycan structure and attachment site identification."
Nilsson J. , Rueetschi U. , Halim A. , Hesse C. , Carlsohn E. , Brinkmalm G. , Larson G.
Nat. Methods6:809-811(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-187;STRUCTURE OF CARBOHYDRATES
tissue: Cerebrospinal fluid.
23.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
24.

"Biological implications of a 3 A structure of dimeric antithrombin."
Carrell R.W. , Stein P.E. , Fermi G. , Wardell M.R.
Structure2:257-270(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS)
25.

"The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions."
Schreuder H.A. , de Boer B. , Dijkema R. , Mulders J. , Theunissen H.J.M. , Grootenhuis P.D.J. , Hol W.G.J.
Nat. Struct. Biol.1:48-54(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS)
26.

"The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site."
Skinner R. , Abrahams J.P. , Whisstock J.C. , Lesk A.M. , Carrel R.W. , Wardell M.R.
J. Mol. Biol.266:601-609(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS)
27.

"Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin."
Skinner R. , Chang W.-S.W. , Jin L. , Pei X.Y. , Huntington J.A. , Abrahams J.P. , Carrell R.W. , Lomas D.A.
J. Mol. Biol.283:9-14(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS)
28.

"Antithrombin III: structural and functional aspects."
Mourey L. , Samama J.-P. , Delarue M. , Choay J. , Lormeau J.C. , Petitou M. , Moras D.
Biochimie72:599-608(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
29.

"Antithrombin III mutation database: first update. For the Thrombin and its Inhibitors Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis."
Lane D.A. , Olds R.J. , Boisclair M. , Chowdhury V. , Thein S.L. , Cooper D.N. , Blajchman M. , Perry D. , Emmerich J. , Aiach M.
Thromb. Haemost.70:361-369(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
30.

"What do dysfunctional serpins tell us about molecular mobility and disease?"
Stein P.E. , Carrell R.W.
Nat. Struct. Biol.2:96-113(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
31.

"Molecular genetics of human antithrombin deficiency."
Perry D.J. , Carrell R.W.
Hum. Mutat.7:7-22(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
32.

"Antithrombin mutation database: 2nd (1997) update."
The plasma coagulation inhibitors subcommittee of the scientific and standardization committee of the international society on thrombosis and haemostasis , Lane D.A. , Bayston T. , Olds R.J. , Fitches A.C. , Cooper D.N. , Millar D.S. , Jochmans K. , Perry D.J. , Okajima K. , Thein S.L. , Emmerich J.
Thromb. Haemost.77:197-211(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D SER-17; PRO-23; ASN-39; CYS-56; LEU-73; CYS-79; HIS-79; SER-79; ASN-87 DEL; CYS-89; LEU-90; CYS-95; SER-95; PRO-98; THR-112; PHE-131; VAL-131; LYS-133; PHE-138-139-LYS DEL; PRO-148; PRO-150; PRO-158; TYR-160; GLN-161; CYS-198; HIS-198; ILE-218 DEL; ASP-219; LYS-219; ARG-257; LYS-269; ILE-283; ASN-316; LYS-334; ARG-412; THR-414; PRO-416; SER-416; VAL-419; ASP-424; CYS-425; HIS-425; PRO-425; LEU-426; CYS-434; LEU-434; SER-434; THR-436; LYS-437; GLY-438; MET-438; LEU-439; THR-439; THR-453; ARG-456; THR-457; ASP-459; LEU-461 AND PHE-462;VARIANTS GLU-30; THR-52 AND CYS-190
33.

"Antithrombin III Toyama: replacement of arginine-47 by cysteine in hereditary abnormal antithrombin III that lacks heparin-binding ability."
Koide T. , Odani S. , Takahashi K. , Ono T. , Sakuragawa N.
Proc. Natl. Acad. Sci. U.S.A.81:289-293(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D CYS-79
34.

"Antithrombin III Basel. Identification of a Pro-Leu substitution in a hereditary abnormal antithrombin with impaired heparin cofactor activity."
Chang J.Y. , Tran T.H.
J. Biol. Chem.261:1174-1176(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D LEU-73
35.

"Antithrombin-III Denver, a reactive site variant."
Stephens A.W. , Thalley B.S. , Hirs C.H.W.
J. Biol. Chem.262:1044-1048(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D LEU-426
36.

"Antithrombin-III-Hamilton: a gene with a point mutation (guanine to adenine) in codon 382 causing impaired serine protease reactivity."
Devrak-Kizuk R. , Chui D.H.K. , Prochownik E.V. , Carter C.J. , Ofosu F.A. , Blajchman M.A.
Blood72:1518-1523(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D THR-414
37.

"Single amino acid substitutions in the reactive site of antithrombin leading to thrombosis. Congenital substitution of arginine 393 to cysteine in antithrombin Northwick Park and to histidine in antithrombin Glasgow."
Erdjument H. , Laned D.A. , Panico M. , di Marzo V. , Morris H.R.
J. Biol. Chem.263:5589-5593(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D CYS-425 AND HIS-425
38.

"Antithrombin Chicago, amino acid substitution of arginine 393 to histidine."
Erdjument H. , Lane D.A. , Panico M. , di Marzo V. , Morris H.R. , Bauer K. , Rosenberg R.D.
Thromb. Res.54:613-619(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D HIS-425
39.

"Antithrombin Rouen-IV 24 Arg-->Cys. The amino-terminal contribution to heparin binding."
Borg J.Y. , Brennan S.O. , Carrell R.W. , George P. , Perry D.J. , Shaw J.
FEBS Lett.266:163-166(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D CYS-56
40.

"Antithrombin Dublin (-3 Val-->Glu): an N-terminal variant which has an aberrant signal peptidase cleavage site."
Daly M. , Bruce D. , Perry D.J. , Price J. , Harper P.L. , O'Meara A. , Carrell R.W.
FEBS Lett.273:87-90(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GLU-30
41.

"Important role of arginine 129 in heparin-binding site of antithrombin III. Identification of a novel mutation arginine 129 to glutamine."
Gandrille S. , Aiach M. , Lane D.A. , Vidaud D. , Molho-Sabatier P. , Caso R. , de Moerloose P. , Fiessinger J.-N. , Clauser E.
J. Biol. Chem.265:18997-19001(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D GLN-161
42.

"Site-directed mutagenesis of alanine-382 of human antithrombin III."
Austin R.C. , Rachubinski R.A. , Blachjman M.A.
FEBS Lett.280:254-258(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT AT3D THR-414;MUTAGENESIS OF ALA-414
43.

"Antithrombin Cambridge II, 384 Ala to Ser. Further evidence of the role of the reactive centre loop in the inhibitory function of the serpins."
Perry D.J. , Daly M. , Harper P.L. , Tait R.C. , Price J. , Walker I.D. , Carrell R.W.
FEBS Lett.285:248-250(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D SER-416
44.

"Antithrombin Budapest 3. An antithrombin variant with reduced heparin affinity resulting from the substitution L99F."
Olds R.J. , Lane D.A. , Boisclair M. , Sas G. , Bock S.C. , Thein S.L.
FEBS Lett.300:241-246(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D PHE-131
45.

"Antithrombin-III Stockholm: a codon 392 (Gly-->Asp) mutation with normal heparin binding and impaired serine protease reactivity."
Blajchman M.A. , Fernandez-Rachubinski F. , Sheffield W.P. , Austin R.C. , Schulman S.
Blood79:1428-1434(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D ASP-424
46.

"Antithrombin III Nagasaki (Ser116-Pro): a heterozygous variant with defective heparin binding associated with thrombosis."
Okajima K. , Abe H. , Maeda S. , Motomura M. , Tsujihata M. , Nagataki S. , Okabe H. , Takatsuki K.
Blood81:1300-1305(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D PRO-148
47.

"A recurrent deletion in the antithrombin gene, AT106-108(-6 bp), identified by DNA heteroduplex detection."
Olds R.J. , Lane D.A. , Beresford C.H. , Abildgaard U. , Hughes P.M. , Thein S.L.
Genomics16:298-299(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D 138-PHE-LYS-139 DEL
48.

"Three novel mutations of antithrombin inducing high-molecular-mass compounds."
Emmerich J. , Vidaud D. , Alhenc-Gelas M. , Chadeuf G. , Gouault-Heilmann M. , Aillaud M.-F. , Aiach M.
Arterioscler. Thromb.14:1958-1965(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D HIS-79 AND TYR-160
49.

"Three novel missense mutations in the antithrombin III (AT3) gene causing recurrent venous thrombosis."
Millar D.S. , Wacey A.I. , Ribando J. , Melissari E. , Laursen B. , Woods P. , Kakkar V.V. , Cooper D.N.
Hum. Genet.94:509-512(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D THR-112; TYR-152 AND ILE-283;VARIANT CYS-190
50.

"Antithrombin-Gly 424 Arg: a novel point mutation responsible for type 1 antithrombin deficiency and neonatal thrombosis."
Jochmans K. , Lissens W. , Vervoort R. , Peeters S. , de Waelwe M. , Liebaers I.
Blood83:146-151(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D ARG-456
51.

"Hereditary antithrombin deficiency: heterogeneity of the molecular basis and mortality in Dutch families."
van Boven H.H. , Olds R.J. , Thein S.L. , Reitsma P.H. , Lane D.A. , Briet E. , Vandenbroucke J.P. , Rosendaal F.R.
Blood84:4209-4213(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D SER-95; THR-453 AND PHE-462
52.

"Thromboembolic disease due to thermolabile conformational changes of antithrombin Rouen-VI (187 Asn-->Asp)."
Bruce D. , Perry D.J. , Borg J.-Y. , Carrell R.W. , Wardell M.R.
J. Clin. Invest.94:2265-2274(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D ASP-219
53.

"Two novel antithrombin variants (L99V and Q118P) which alter the heparin binding domain."
Chowdhury V. , Olds R.J. , Lane D.A. , Mille B. , Pabinger I. , Thein S.L.
Nouv. Rev. Fr. Hematol.86:268-268(1994)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D VAL-131 AND PRO-150
54.

"Molecular basis of antithrombin type I deficiency: the first large in-frame deletion and two novel mutations in exon 6."
Emmerich J. , Chadeuf G. , Alhenc-Gelas M. , Gouault-Heilman M. , Toulon P. , Fiessinger J.-N. , Aiach M.
Thromb. Haemost.72:534-539(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D 273-LYS--LYS-307 DEL
55.

"Antithrombin III Kumamoto II; a single mutation at Arg393-His increased the affinity of antithrombin III for heparin."
Okajima K. , Abe H. , Wagatsuma M. , Okabe H. , Takatsuki K.
Am. J. Hematol.48:12-18(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D HIS-425
56.

"Antithrombin Morioka (Cys 95-Arg): a novel missense mutation causing type I antithrombin deficiency."
Ozawa T. , Takikawa Y. , Niiya K. , Fujiwara T. , Suzuki K. , Sato S. , Sakuragawa N.
Thromb. Haemost.77:403-403(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D ARG-127
57.

"Impaired cotranslational processing as a mechanism for type I antithrombin deficiency."
Fitches A.C. , Appleby R. , Lane D.A. , De Stefano V. , Leone G. , Olds R.J.
Blood92:4671-4676(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D PRO-23
58.

"The molecular basis of antithrombin deficiency in Belgian and Dutch families."
Jochmans K. , Lissens W. , Seneca S. , Capel P. , Chatelain B. , Meeus P. , Osselaer J.C. , Peerlinck K. , Seghers J. , Slacmeulder M. , Stibbe J. , van de Loo J. , Vermylen J. , Liebaers I. , De Waele M.
Thromb. Haemost.80:376-381(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D ARG-32; LEU-73; CYS-79; HIS-198; ARG-257 AND ARG-412
59.

"Familial overexpression of beta-antithrombin caused by an Asn135-to-Thr substitution."
Bayston T.A. , Tripodi A. , Mannucci P.M. , Thompson E. , Ireland H. , Fitches A.C. , Hananeia L. , Olds R.J. , Lane D.A.
Blood93:4242-4247(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-167
60.

"Molecular bases of antithrombin deficiency in French families: identification of seven novel mutations in the antithrombin gene."
Picard V. , Bura A. , Emmerich J. , Alhenc-Gelas M. , Biron C. , Houbouyan-Reveillard L.L. , Molho P. , Labatide-Alanore A. , Sie P. , Toulon P. , Verdy E. , Aiach M.
Br. J. Haematol.110:731-734(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D PHE-214; PRO-223; ILE-243; THR-251; VAL-283 AND PRO-397
61.

"Two novel gene mutations in type I antithrombin deficiency."
Niiya K. , Kiguchi T. , Dansako H. , Fujimura K. , Fujimoto T. , Iijima K. , Tanimoto M. , Harada M.
Int. J. Hematol.74:469-472(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D 152-HIS--PHE-154 DEL
62.

"Intracerebral hemorrhage associated with a novel antithrombin gene mutation in a neonate."
Baud O. , Picard V. , Durand P. , Duchemin J. , Proulle V. , Alhenc-Gelas M. , Devictor D. , Dreyfus M.
J. Pediatr.139:741-743(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D PRO-223
63.

"Antithrombin 'DREUX' (Lys 114Glu): a variant with complete loss of heparin affinity."
Mushunje A. , Zhou A. , Huntington J.A. , Conard J. , Carrell R.W.
Thromb. Haemost.88:436-443(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D GLU-146
64.

"Antithrombin Phe229Leu: a new homozygous variant leading to spontaneous antithrombin polymerization in vivo associated with severe childhood thrombosis."
Picard V. , Dautzenberg M.-D. , Villoutreix B.O. , Orliaguet G. , Alhenc-Gelas M. , Aiach M.
Blood102:919-925(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D LEU-261
65.

"Five novel and four recurrent point mutations in the antithrombin gene causing venous thrombosis."
Nagaizumi K. , Inaba H. , Amano K. , Suzuki M. , Arai M. , Fukutake K.
Int. J. Hematol.78:79-83(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D LYS-121; HIS-178; CYS-425; HIS-425 AND PRO-441
66.

"Molecular basis of inherited antithrombin deficiency in Portuguese families: identification of genetic alterations and screening for additional thrombotic risk factors."
David D. , Ribeiro S. , Ferrao L. , Gago T. , Crespo F.
Am. J. Hematol.76:163-171(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D LEU-179; CYS-425 AND LEU-426
67.

"Retinal vein occlusion associated with antithrombin deficiency secondary to a novel G9840C missense mutation."
Kuhli C. , Jochmans K. , Scharrer I. , Luechtenberg M. , Hattenbach L.-O.
Arch. Ophthalmol.124:1165-1169(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT3D HIS-398
68.

"Type II antithrombin deficiency caused by a founder mutation Pro73Leu in the Finnish population: clinical picture."
Puurunen M. , Salo P. , Engelbarth S. , Javela K. , Perola M.
J. Thromb. Haemost.11:1844-1849(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT3D PHE-53; LEU-73; ASP-125; PRO-170; ASN-218; GLY-248; PRO-293; ARG-401; CYS-425; GLY-438 AND ALA-439;VARIANT GLU-30

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