ANAPC10 ELISA Kit for Human(Homo sapiens) | EIAab.comANAPC10 ELISA Kit for Human(Homo sapiens)

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ANAPC10 (Gene name),

Anaphase-promoting complex subunit 10 (Protein name ), APC10_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ANAPC10(APC10);

Protein name:

Anaphase-promoting complex subunit 10(APC10);

Alternative:

Cyclosome subunit 10;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

The APC/C is composed of at least 12 subunits. The C-terminus of APC10 binds to CDC27/APC3.

Function:

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

185

Sequence:

50:

100:

150:

185:

THMRQIKIYT | PVEESSIGKF | PRCTTIDFMM | YRSIR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000310071

String:

Q9UM13

KEGG:

hsa:10393

MIM:

613745

Pfam:

PF03256

UniGene:

Hs.480876

SMR:

Q9UM13

Uniprot:

Q9UM13

FOR

ELISA Kit for Human APC10

CLIA Kit for Human APC10

Polyclonal Antibody for Human APC10

Monoclonal Antibody for Human APC10

Protein for Human APC10

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex."
Grossberger R. , Gieffers C. , Zachariae W. , Podtelejnikov A.V. , Schleiffer A. , Nasmyth K. , Mann M. , Peters J.-M.
J. Biol. Chem.274:14500-14507(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Identification of human APC10/Doc1 as a subunit of anaphase promoting complex."
Kurasawa Y. , Todokoro K.
Oncogene18:5131-5137(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Wiemann S. , Weil B. , Wellenreuther R. , Gassenhuber J. , Glassl S. , Ansorge W. , Boecher M. , Bloecker H. , Bauersachs S. , Blum H. , Lauber J. , Duesterhoeft A. , Beyer A. , Koehrer K. , Strack N. , Mewes H.-W. , Ottenwaelder B. , Obermaier B. , more...
Genome Res.11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
4.

NIEHS SNPs program
Submitted (2005-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLN-46
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
7.

"Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex."
Jin L. , Williamson A. , Banerjee S. , Philipp I. , Rape M.
Cell133:653-665(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF THE APC/C
8.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT THR-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
9.

"Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex."
Wendt K.S. , Vodermaier H.C. , Jacob U. , Gieffers C. , Gmachl M. , Peters J.-M. , Huber R. , Sondermann P.
Nat. Struct. Biol.8:784-788(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS);INTERACTION WITH CDC27
10.

"Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C."
Dube P. , Herzog F. , Gieffers C. , Sander B. , Riedel D. , Mueller S.A. , Engel A. , Peters J.-M. , Stark H.
Mol. Cell20:867-879(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ELECTRON MICROSCOPY OF THE APC/C
11.

"Molecular architecture and mechanism of the anaphase-promoting complex."
Chang L. , Zhang Z. , Yang J. , McLaughlin S.H. , Barford D.
Nature513:388-393(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE APC/C;SUBUNIT

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