APOA4 ELISA Kit for Human(Homo sapiens) | EIAab.comAPOA4 ELISA Kit for Human(Homo sapiens)

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APOA4 (Gene name),

Apolipoprotein A-IV (Protein name ), APOA4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

APOA4;

Protein name:

Apolipoprotein A-IV(Apo-AIV;ApoA-IV);

Alternative:

Apolipoprotein A4;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

396

Sequence:

50:

100:

150:

200:

250:

300:

350:

396:

VNSFFSTFKE | KESQDKTLSL | PELEQQQEQQ | QEQQQEQVQM | LAPLES

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.1247

String:

P06727

STRING:

9606.ENSP00000350425

SMR:

P06727

MIM:

107690

Pfam:

PF01442

Uniprot:

P06727

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ELISA Kit for Human Apo-AIV

Cat.:

E1967h

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96T

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ELISA Kit for Human Apo-AIV

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E1967m

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96T

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ELISA Kit for Human Apo-AIV

Cat.:

E1967b

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96T

ELISA Kit for Human Apo-AIV

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E1967p

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96T

ELISA Kit for Human Apo-AIV

Cat.:

E1967r

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96T

CLIA Kit for Human Apo-AIV

Cat.:

U1967p

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96T

CLIA Kit for Human Apo-AIV

Cat.:

U1967b

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96T

CLIA Kit for Human Apo-AIV

Cat.:

U1967r

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96T

CLIA Kit for Human Apo-AIV

Cat.:

U1967m

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96T

CLIA Kit for Human Apo-AIV

Cat.:

U1967h

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96T

Polyclonal Antibody for Human Apo-AIV

Cat.:

P1967Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Apo-AIV

Cat.:

P1967Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Apo-AIV

Cat.:

P1967Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Apo-AIV

Monoclonal Antibody for Human Apo-AIV

Protein for Human Apo-AIV

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Structure, evolution, and tissue-specific synthesis of human apolipoprotein AIV."
Karathanasis S.K. , Yunis I.
Biochemistry25:3962-3970(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT LYS-279
2.

"Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4)."
Karathanasis S.K. , Oettgen P. , Haddad I.A. , Antonarakis S.E.
Proc. Natl. Acad. Sci. U.S.A.83:8457-8461(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT LYS-279
3.

"Structure and expression of the human apolipoprotein A-IV gene."
Elshourbagy N.A. , Walker D.W. , Paik Y.K. , Boguski M.S. , Freeman M. , Gordon J.I. , Taylor J.M.
J. Biol. Chem.262:7973-7981(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT APOA-IV*2 HIS-380
4.

"The primary structure of human apolipoprotein A-IV."
Yang C. , Gu Z.W. , Xiong W. , Rosseneu M. , Yang H.X. , Lee B.M. , Gotto A.M. Jr. , Chan L.
Biochim. Biophys. Acta1002:231-237(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Intestine.
5.

"The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster."
Fullerton S.M. , Buchanan A.V. , Sonpar V.A. , Taylor S.L. , Smith J.D. , Carlson C.S. , Salomaa V. , Stengaard J.H. , Boerwinkle E. , Clark A.G. , Nickerson D.A. , Weiss K.M.
Hum. Genet.115:36-56(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS MET-13; HIS-77; SER-147; SER-161; SER-367 AND HIS-380
6.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT SER-147
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Colon.
8.

"The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III."
Elshourbagy N.A. , Walker D.W. , Boguski M.S. , Gordon J.I. , Taylor J.M.
J. Biol. Chem.261:1998-2002(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 21-396;VARIANT APOA-IV*2 HIS-380
9.

"Biosynthesis of human preapolipoprotein A-IV."
Gordon J.I. , Bisgaier C.L. , Sims H.F. , Sachdev O.P. , Glickman R.M. , Strauss A.W.
J. Biol. Chem.259:468-474(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SIGNAL SEQUENCE CLEAVAGE SITE
10.

"Genetic polymorphism of apolipoprotein A-IV."
Lohse P. , Brewer H.B. Jr.
Curr. Opin. Lipidol.2:90-95(1991)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON POLYMORPHISM
11.

"Genetic polymorphism of human plasma apolipoprotein A-IV is due to nucleotide substitutions in the apolipoprotein A-IV gene."
Lohse P. , Kindt M.R. , Rader D.J. , Brewer H.B. Jr.
J. Biol. Chem.265:10061-10064(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALLELES APOA-IV*1 AND APOA-IV*2;VARIANT HIS-380
12.

"Human plasma apolipoproteins A-IV-0 and A-IV-3. Molecular basis for two rare variants of apolipoprotein A-IV-1."
Lohse P. , Kindt M.R. , Rader D.J. , Brewer H.B. Jr.
J. Biol. Chem.265:12734-12739(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALLELES A-IV*0 AND A-IV*3;VARIANTS LYS-250 AND GLU-GLN-GLN-GLN-381 INS
13.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"The structure of dimeric apolipoprotein A-IV and its mechanism of self-association."
Deng X. , Morris J. , Dressmen J. , Tubb M.R. , Tso P. , Jerome W.G. , Davidson W.S. , Thompson T.B.
Structure20:767-779(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 84-355;SUBUNIT
15.

"The mutation causing the common apolipoprotein A-IV polymorphism is a glutamine to histidine substitution of amino acid 360."
Tenkanen H. , Lukka M. , Jauhiainen M. , Metso J. , Baumann M. , Peltonen L. , Ehnholm C.
Arterioscler. Thromb.11:851-856(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-380
16.

"Three genetic variants of human plasma apolipoprotein A-IV: apoA-IV-1(Thr-347-->Ser), apoA-IV-0(Lys-167-->Glu,Gln-360-->His), and apoA-IV-3(Glu-165-->Lys)."
Lohse P. , Kindt M.R. , Rader D.J. , Brewer H.B. Jr.
J. Biol. Chem.266:13513-13518(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALLELES A-IV*0; A-IV*1; A-IV*2 AND A-IV*3;VARIANTS LYS-185; GLU-187; SER-367 AND HIS-380
17.

Lohse P. , Kindt M.R. , Rader D.J. , Brewer H.B. Jr.
J. Biol. Chem.266:19866-19866(1991)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
18.

"Nonsynonymous polymorphic sites in the apolipoprotein (apo) A-IV gene are associated with changes in the concentration of apo B- and apo A-I-containing lipoproteins in a normal population."
von Eckardstein A. , Funke H. , Schulte M. , Erren M. , Schulte H. , Assmann G.
Am. J. Hum. Genet.50:1115-1128(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MET-13
19.

"A novel polymorphism of apolipoprotein A-IV is the result of an asparagine to serine substitution at residue 127."
Tenkanen H. , Koskinen P. , Metso J. , Baumann M. , Lukka M. , Kauppinen-Makelin R. , Kontula K. , Taskinen M.R. , Manttari M. , Manninen V. , Ehnholm C.
Biochim. Biophys. Acta1138:27-33(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-147
20.

"Molecular basis of a unique African variant (A-IV 5) of human apolipoprotein A-IV and its significance in lipid metabolism."
Kamboh M.I. , Williams E.R. , Law J.C. , Aston C.E. , Bunker C.H. , Ferrell R.E. , Pollitzer W.S.
Genet. Epidemiol.9:379-388(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALLELE A-IV*5;VARIANT GLU-GLN-GLN-GLN-381 INS
21.

"Apolipoprotein A-IV polymorphism in the Hungarian population: gene frequencies, effect on lipid levels, and sequence of two new variants."
Menzel H.J. , Dieplinger H. , Sandholzer C. , Karadi I. , Utermann G. , Csaszar A.
Hum. Mutat.5:58-65(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BUDAPEST-2 LYS-44; BUDAPEST-1 CYS-305 AND SER-367
22.

"Two novel apolipoprotein A-IV variants in individuals with familial combined hyperlipidemia and diminished levels of lipoprotein lipase activity."
Deeb S.S. , Nevin D.N. , Iwasaki L. , Brunzell J.D.
Hum. Mutat.8:319-325(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SEATTLE-3 SER-161; SEATTLE-1 LEU-178 AND SEATTLE-2 GLN-264
23.

"Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis."
Halushka M.K. , Fan J.-B. , Bentley K. , Hsie L. , Shen N. , Weder A. , Cooper R. , Lipshutz R. , Chakravarti A.
Nat. Genet.22:239-247(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-380

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