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Index > Protein center > APOC3(Gene name) > Human
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  • APOC3 (Gene name),
  • Apolipoprotein C-III (Protein name ),  APOC3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    APOC3;
    Protein name:
    Apolipoprotein C-III(Apo-CIII;ApoC-III);
    Alternative:
    Apolipoprotein C3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Inhibits lipoprotein lipase and hepatic lipase and decreases the uptake of lymph chylomicrons by hepatic cells. This suggests that it delays the catabolism of triglyceride-rich particles.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    99
    Sequence:
    50:
    MQPRVLLVVA | LLALLASARA | SEAEDASLLS | FMQGYMKHAT | KTAKDALSSV | 
    99:
    QESQVAQQAR | GWVTDGFSSL | KDYWSTVKDK | FSEFWDLDPE | VRPTSAVAA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    SMR:
    UniGene:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Apo-CIII
    Cat.:
    E1890h
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    ELISA Kit for Human Apo-CIII
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    E1890m
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    Packing:
    96T
    ELISA Kit for Human Apo-CIII
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    E1890r
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    ELISA Kit for Human Apo-CIII
    Cat.:
    E1890p
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    96T
    ELISA Kit for Human Apo-CIII
    Cat.:
    E1890d
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    96T
    ELISA Kit for Human Apo-CIII
    Cat.:
    E1890b
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    Packing:
    96T
    CLIA Kit for Human Apo-CIII
    Cat.:
    U1890p
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    CLIA Kit for Human Apo-CIII
    Cat.:
    U1890d
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    MSDS:
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    CLIA Kit for Human Apo-CIII
    Cat.:
    U1890b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Apo-CIII
    Cat.:
    U1890m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Apo-CIII
    Cat.:
    U1890h
    Price:
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    Range:
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    CLIA Kit for Human Apo-CIII
    Cat.:
    U1890r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Apo-CIII
    Polyclonal Antibody for Human Apo-CIII
    Cat.:
    P1890Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Apo-CIII
    Polyclonal Antibody for Human Apo-CIII
    Cat.:
    P1890Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Apo-CIII
    Cat.:
    P1890Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Apo-CIII
    Monoclonal Antibody for Human Apo-CIII
    Monoclonal Antibody for Human Apo-CIII
    Monoclonal Antibody for Human Apo-CIII
    Monoclonal Antibody for Human Apo-CIII
    Monoclonal Antibody for Human Apo-CIII
    Monoclonal Antibody for Human Apo-CIII
    Protein for Human Apo-CIII
    Protein for Human Apo-CIII
    Protein for Human Apo-CIII
    Protein for Human Apo-CIII
    Protein for Human Apo-CIII
    Protein for Human Apo-CIII

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    References
    1. 1.
      "Isolation and sequence analysis of the human apolipoprotein CIII gene and the intergenic region between the apo AI and apo CIII genes."
      Protter A.A. , Levy-Wilson B. , Miller J. , Bencen G. , White T. , Seilhamer J.J.
      DNA3:449-456(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    2. 2.
      "Isolation and DNA sequence of full-length cDNA for human preapolipoprotein CIII."
      Levy-Wilson B. , Appleby V. , Protter A.A. , Auperin D. , Seilhamer J.J.
      DNA3:359-364(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Isolation and characterization of cDNA clones corresponding to two different human apoC-III alleles."
      Karathanasis S.K. , Zannis V.I. , Breslow J.L.
      J. Lipid Res.26:451-456(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    4. 4.
      "Human apolipoproteins AI, AII, CII and CIII. cDNA sequences and mRNA abundance."
      Sharpe C.R. , Sidoli A. , Shelley C.S. , Lucero M.A. , Shoulders C.C. , Baralle F.E.
      Nucleic Acids Res.12:3917-3932(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
      tissue: Spleen.
    7. 7.
      "Amino acid sequence of human plasma apolipoprotein C-III from normolipidemic subjects."
      Hospattankar A.V. , Brewer H.B. Jr. , Ronan R. , Fairwell T.
      FEBS Lett.197:67-73(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-99
    8. 8.
      "The complete amino acid sequence of alanine apolipoprotein (apoC-3), and apolipoprotein from human plasma very low density lipoproteins."
      Brewer H.B. Jr. , Shulman R. , Herbert P. , Ronan R. , Wehrly K.
      J. Biol. Chem.249:4975-4984(1974) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-99
    9. 9.
      "An ABC of apolipoprotein C-III: a clinically useful new cardiovascular risk factor?"
      Chan D.C. , Chen M.M. , Ooi E.M. , Watts G.F.
      Int. J. Clin. Pract.62:799-809(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    10. 10.
      "Enrichment of glycopeptides for glycan structure and attachment site identification."
      Nilsson J. , Rueetschi U. , Halim A. , Hesse C. , Carlsohn E. , Brinkmalm G. , Larson G.
      Nat. Methods6:809-811(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT THR-94;STRUCTURE OF CARBOHYDRATES
      tissue: Cerebrospinal fluid.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Apolipoprotein C-III and hepatic triglyceride-rich lipoprotein production."
      Yao Z. , Wang Y.
      Curr. Opin. Lipidol.23:206-212(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    13. 13.
      "Identification of new apolipoprotein-CIII glycoforms with ultrahigh resolution MALDI-FTICR mass spectrometry of human sera."
      Nicolardi S. , van der Burgt Y.E. , Dragan I. , Hensbergen P.J. , Deelder A.M.
      J. Proteome Res.12:2260-2268(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT THR-94;STRUCTURE OF CARBOHYDRATES;IDENTIFICATION BY MASS SPECTROMETRY
    14. 14.
      "Molecular cloning of a human apoC-III variant: Thr 74-->Ala 74 mutation prevents O-glycosylation."
      Maeda H. , Hashimoto R.K. , Oguro T. , Hiraga S. , Uzawa H.
      J. Lipid Res.28:1405-1409(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT C-III-0 ALA-94;GLYCOSYLATION AT THR-94
    15. 15.
      "Apolipoprotein C-III(Lys-58-->Glu). Identification of an apolipoprotein C-III variant in a family with hyperalphalipoproteinemia."
      von Eckardstein A. , Holz H. , Sandkamp M. , Weng W. , Funke H. , Assmann G.
      J. Clin. Invest.87:1724-1731(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HALP2 GLU-78
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