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Index > Protein center > APOL1(Gene name) > Human
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  • APOL1 (Gene name),
  • Apolipoprotein L1 (Protein name ),  APOL1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    APOL1(APOL);
    Protein name:
    Apolipoprotein L1;
    Alternative:
    Apolipoprotein L-I(ApoL-I);Apolipoprotein L(Apo-L;ApoL);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles.
    Function:
    May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    398
    Sequence:
    50:
    MEGAALLRVS | VLCIWMSALF | LGVGVRAEEA | GARVQQNVPS | GTDTGDPQSK | 
    100:
    PLGDWAAGTM | DPESSIFIED | AIKYFKEKVS | TQNLLLLLTD | NEAWNGFVAA | 
    150:
    AELPRNEADE | LRKALDNLAR | QMIMKDKNWH | DKGQQYRNWF | LKEFPRLKSE | 
    200:
    LEDNIRRLRA | LADGVQKVHK | GTTIANVVSG | SLSISSGILT | LVGMGLAPFT | 
    250:
    EGGSLVLLEP | GMELGITAAL | TGITSSTMDY | GKKWWTQAQA | HDLVIKSLDK | 
    300:
    LKEVREFLGE | NISNFLSLAG | NTYQLTRGIG | KDIRALRRAR | ANLQSVPHAS | 
    350:
    ASRPRVTEPI | SAESGEQVER | VNEPSILEMS | RGVKLTDVAP | VSFFLVLDVV | 
    398:
    YLVYESKHLH | EGAKSETAEE | LKKVAQELEE | KLNILNNNYK | ILQADQEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Apolipoprotein L1
    Cat.:
    E10479h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Apolipoprotein L1
    Cat.:
    U10479h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human Apolipoprotein L1
    Cat.:
    P10479Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Apolipoprotein L1
    Protein for Human Apolipoprotein L1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L."
      Duchateau P.N. , Pullinger C.R. , Orellana R.E. , Kunitake S.T. , Naya-Vigne J. , O'Connor P.M. , Malloy M.J. , Kane J.P.
      J. Biol. Chem.272:25576-25582(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 28-63;VARIANTS LYS-150; ILE-228 AND LYS-255
      tissue: Pancreas.
    2. 2.
      "Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene."
      Duchateau P.N. , Pullinger C.R. , Cho M.H. , Eng C. , Kane J.P.
      J. Lipid Res.42:620-630(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SEQUENCE REVISION TO 155 AND 346;VARIANTS LYS-150; ILE-228 AND LYS-255
      tissue: Pancreas.
    3. 3.
      "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution."
      Page N.M. , Butlin D.J. , Lomthaisong K. , Lowry P.J.
      Genomics74:71-78(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Placenta.
    4. 4.
      "The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue."
      Monajemi H. , Fontijn R.D. , Pannekoek H. , Horrevoets A.J.G.
      Genomics79:539-546(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS ILE-228; LYS-255; GLY-342 AND MET-384
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANTS LYS-150; ILE-228 AND LYS-255
      tissue: Placenta.
    6. 6.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-261
      tissue: Plasma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] THR-188
    10. 10.
      "Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene."
      Tzur S. , Rosset S. , Shemer R. , Yudkovsky G. , Selig S. , Tarekegn A. , Bekele E. , Bradman N. , Wasser W.G. , Behar D.M. , Skorecki K.
      Hum. Genet.128:345-350(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS FSGS4 GLY-342 AND MET-384
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS FSGS4 GLY-342 AND MET-384
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