Aptx ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAptx ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Aptx(Gene name) > Rat

Aptx (Gene name),

Aprataxin (Protein name ), APTX_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Aptx;

Protein name:

Aprataxin;

Alternative:

Forkhead-associated domain histidine triad-like protein(FHA-HIT);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with single-strand break repair proteins XRCC1, XRCC4, ADPRT and p53/TP53. Interacts with NCL. Interacts (via FHA-like domain) with MDC1 (phosphorylated).

Function:

DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

Subcellular Location:

Nucleus nucleoplasm Nucleus nucleolus Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage. Colocalizes with MDC1 at sites of DNA double-strand breaks. Interaction with NCL is required for nucleolar localization.

Protein Attributes:

Sequence length:

329

Sequence:

50:

100:

150:

200:

250:

300:

329:

KLPLRCHECQ | QLLPSIPQLK | EHLRKHWGG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:259271

UniGene:

Rn.50459

String:

Q8K4H4

STRING:

10116.ENSRNOP00000009176

Uniprot:

Q8K4H4

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ELISA Kit for Rat Aprataxin

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E9623p

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ELISA Kit for Rat Aprataxin

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E9623d

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ELISA Kit for Rat Aprataxin

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E9623h

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ELISA Kit for Rat Aprataxin

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E9623r

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ELISA Kit for Rat Aprataxin

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E9623m

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ELISA Kit for Rat Aprataxin

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E9623b

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ELISA Kit for Rat Aprataxin

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E9623c

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CLIA Kit for Rat Aprataxin

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U9623d

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96T

CLIA Kit for Rat Aprataxin

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U9623m

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96T

CLIA Kit for Rat Aprataxin

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U9623b

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96T

CLIA Kit for Rat Aprataxin

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U9623r

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96T

CLIA Kit for Rat Aprataxin

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U9623c

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96T

CLIA Kit for Rat Aprataxin

Cat.:

U9623p

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96T

CLIA Kit for Rat Aprataxin

Cat.:

U9623h

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Polyclonal Antibody for Rat Aprataxin

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P9623Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat Aprataxin

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P9623Rb-r

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Polyclonal Antibody for Rat Aprataxin

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P9623Rb-m

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40ug/0.2ml

Monoclonal Antibody for Rat Aprataxin

Protein for Rat Aprataxin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Identification of FHA-HIT as a novel nuclear protein involved in cell-cycle regulation."
Huang C.-H. , Chen H. , Peng J. , Chen Y.
Submitted (2001-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.

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