Gene name:
Arap1 (Centd2;Kiaa0782) ;
Protein name:
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 ;
Alternative:
Centaurin-delta-2 (Cnt-d2) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with TNFRSF10A.
Function:
Phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Has a preference for ARF1 and ARF5.
Subcellular Location:
Cytoplasm
Golgi apparatus
Golgi stack membrane
Peripheral membrane protein
Cell membrane
Protein Attributes:
50:
MAEGYDAALS | VAEWLRALHL | EQYTALFEQH | GLVWATECQG | LSDAGLLDMG |
100:
MHLPGHRRRI | LAGLHRAHAP | PVPLPRPAPR | PVPMKRHIFR | SPPVPVTPPE |
150:
PPPTAGEDEG | LPAAPPIPPR | RSCLPPACFT | PTSTAAPDPV | LPPLPAKRHL |
200:
VEPSVPPVPP | RTGPPYPQAS | LLAKEELLLP | SVSPRSQPEP | AETPSTLLPA |
250:
FPQGPLQPPS | PPPCPPVIPP | KPPRLLPEFD | DSDYDDVPEE | GPGAPASVMT |
300:
KEEPLPSRVP | RAVRVASLLS | EGEELSGDDS | EDDDDHAYEG | IPNGGWPTSG |
350:
LNPPLRSLIP | DLPLHPMDEL | PGGPTPITPV | IKAGWLDKNP | PQGSYIYQKR |
400:
WVRLDADYLR | YFDSNKDAYS | KRFVPVACIC | RVAPIGDQKF | EVITNNRTFA |
450:
FRAESDVERN | EWMQALQQAV | VEHRARFRLS | SASVLGVRGS | EQPDRAGSLE |
500:
LRGFKNKLYV | AVTGDKVQLY | KNLEEFHLGI | GITFIDMNVG | NVKEVDRRSF |
550:
DLTTPYRIFS | FSADSELEKE | QWLEAMQGAI | AEALSTSEVA | ERIWAAAPNR |
600:
FCADCGAAQP | DWASINLCVV | ICKRCAGEHR | GLGAGVSKVR | SLKMDRKVWT |
650:
EALIQLFLHL | GNGPGNHFWA | ANVPPSEALE | PSSSPGARRY | HLEAKYREGK |
700:
YRRYHPLFGN | QEELDKALCA | AVTTTDLAET | QALLGCGAGV | SCFSGDPAAP |
750:
TPLALAEQAG | QTLQMEFLRN | NQSTEVPRLD | SVKPLEKHYS | VTLPTVSHSG |
800:
FLYKTASAGK | PLQDRRAREE | FSRRWCVLSD | GVLSYYENER | AVTPNGEIRA |
850:
SEIVCLAVSP | LDTHGFEHTF | EVYTEGERLY | LFGLENAELA | HEWVKCIAKA |
900:
FVPPLAEDLL | ARDFERLGRL | PCKAGLSLQQ | AQEGWFALTG | SELRAVFPEG |
950:
PWEEPLQLRK | LQELSIQGDS | ENQVLVLVER | RRTLYIQGER | RLDFMAWLGV |
1000:
IQKAAASLGD | TLSEQQLGDS | DIPVIVYRCV | DYITQCGLTS | EGIYRKCGQT |
1050:
SKTQRLLDSL | RQDARSVHLK | EGEQHVDDVS | SALKRFLRDL | PDGLFTRAQR |
1100:
LAWLEASEIE | DEEEKISRYR | ELLVHLPPVN | RATVKALISH | LYCVQCFSDT |
1150:
NQMNTHNLAI | VFGPTLFQTD | GQDYKAGKVV | EDLINHYVVV | FSVDEEELRK |
1200:
QREEVTAIVK | MRVAGTASGT | QHAGDFICTV | YLEEKKVETE | QHVKIPASMT |
1250:
AEELTLEILD | RRNVSIREKD | YWTCFEVNEK | EEAERPLHFA | EKVLPIVHGL |
1300:
GIDSHLVVKK | YQSMEAMLLY | LASRVGDTKH | GMMKFREDRS | LLGLGLPSGG |
1350:
FHDRYFILNS | SCLRLYKEVR | SQRPWSGAPE | TSHRPEKEWP | VKSLKVYLGV |
1400:
KKKLRPPTCW | GFTVVHETEK | HEKQQWYLCC | DTQMELREWF | ATFLSVQHDG |
1450:
LVWPSEPSRV | SRAVPEVRMG | SVSLIPLRGS | ENEMRRSVAA | FTADPLSLLR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
ELISA Kit for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
CLIA Kit for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
CLIA Kit for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Polyclonal Antibody for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Polyclonal Antibody for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Monoclonal Antibody for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Monoclonal Antibody for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Protein for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
Protein for Mouse Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain :
C57BL/6J .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
strain :
C57BL/6J .
tissue :
Bone .
tissue :
Bone marrow macrophage .
tissue :
Cerebellum .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1320-1452 (ISOFORM 2/3)
strain :
FVB/N .
tissue :
Brain .
tissue :
Liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 295-1452 (ISOFORM 2/3)
tissue :
Brain .