Arf1 ELISA Kit for Mouse(Mus musculus) | EIAab.comArf1 ELISA Kit for Mouse(Mus musculus)

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Arf1 (Gene name),

ADP-ribosylation factor 1 (Protein name ), ARF1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Arf1;

Protein name:

ADP-ribosylation factor 1;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with PRKCABP, PSCD2, ASAP2, HERC1 and PIP5K1A (By similarity). Interacts with GGA1 and ARHGAP21. Interacts with ARFGAP1, which hydrolyzes GTP and thus, regulates its function. Interacts with PI4KB in the Golgi complex. Interacts with NCS1/FREQ in the Golgi and at the plasma membrane.

Function:

GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles.

Subcellular Location:

Golgi apparatus Cytoplasm perinuclear region

Protein Attributes:

Sequence length:

181

Sequence:

50:

100:

150:

181:

RNWYIQATCA | TSGDGLYEGL | DWLSNQLRNQ | K

3D Structure: