Arfgap1 ELISA Kit for Mouse(Mus musculus) | EIAab.comArfgap1 ELISA Kit for Mouse(Mus musculus)

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Arfgap1 (Gene name),

ADP-ribosylation factor GTPase-activating protein 1 (Protein name ), ARFG1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Arfgap1(Arf1gap);

Protein name:

ADP-ribosylation factor GTPase-activating protein 1(ARF GAP 1);

Alternative:

ARF1-directed GTPase-activating protein;ADP-ribosylation factor 1 GTPase-activating protein(ARF1 GAP);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with ARF1. Interacts with the COPI coat proteins, KDELR1 and RNP24. It is probably a component of the COPI coat protein complex. The interaction with RNP24 inhibits the GAP activity.

Function:

GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and RNP24. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine.

Subcellular Location:

Cytoplasm Golgi apparatus Associates with the Golgi complex.

Protein Attributes:

Sequence length:

414

Sequence:

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