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Index > Protein center > ARG1(Gene name) > Human
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  • ARG1 (Gene name),
  • Arginase-1 (Protein name ),  ARGI1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    ARG1;
    Protein name:
    Arginase-1;
    Alternative:
    Type I arginase;Liver-type arginase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer.
    Function:
    N/A
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    322
    Sequence:
    50:
    MSAKSRTIGI | IGAPFSKGQP | RGGVEEGPTV | LRKAGLLEKL | KEQECDVKDY | 
    100:
    GDLPFADIPN | DSPFQIVKNP | RSVGKASEQL | AGKVAEVKKN | GRISLVLGGD | 
    150:
    HSLAIGSISG | HARVHPDLGV | IWVDAHTDIN | TPLTTTSGNL | HGQPVSFLLK | 
    200:
    ELKGKIPDVP | GFSWVTPCIS | AKDIVYIGLR | DVDPGEHYIL | KTLGIKYFSM | 
    250:
    TEVDRLGIGK | VMEETLSYLL | GRKKRPIHLS | FDVDGLDPSF | TPATGTPVVG | 
    300:
    GLTYREGLYI | TEEIYKTGLL | SGLDIMEVNP | SLGKTPEEVT | RTVNTAVAIT | 
    322:
    LACFGLAREG | NHKPIDYLNP | PK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    MIM:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Arginase-1
    Cat.:
    E1120h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Arginase-1
    Cat.:
    E1120r
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Arginase-1
    Cat.:
    E1120m
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Human Arginase-1
    Cat.:
    E1120b
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Arginase-1
    MSDS:
    Please sign in first.
    ELISA Kit for Human Arginase-1
    Cat.:
    E1120p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Arginase-1
    Cat.:
    U1120b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Arginase-1
    Cat.:
    U1120p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Arginase-1
    Cat.:
    U1120m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Arginase-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human Arginase-1
    Cat.:
    U1120r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Arginase-1
    Cat.:
    U1120h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human Arginase-1
    Polyclonal Antibody for Human Arginase-1
    Cat.:
    P1120Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Arginase-1
    Cat.:
    P1120Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Arginase-1
    Cat.:
    P1120Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Arginase-1
    Polyclonal Antibody for Human Arginase-1
    Monoclonal Antibody for Human Arginase-1
    Monoclonal Antibody for Human Arginase-1
    Monoclonal Antibody for Human Arginase-1
    Monoclonal Antibody for Human Arginase-1
    Monoclonal Antibody for Human Arginase-1
    Monoclonal Antibody for Human Arginase-1
    Protein for Human Arginase-1
    Protein for Human Arginase-1
    Protein for Human Arginase-1
    Protein for Human Arginase-1
    Protein for Human Arginase-1
    Protein for Human Arginase-1

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    References
    1. 1.
      "Molecular cloning and nucleotide sequence of cDNA for human liver arginase."
      Haraguchi Y. , Takiguchi M. , Amaya Y. , Kawamoto S. , Matsuda I. , Mori M.
      Proc. Natl. Acad. Sci. U.S.A.84:412-415(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    2. 2.
      "Human liver-type arginase gene: structure of the gene and analysis of the promoter region."
      Takiguchi M. , Haraguchi Y. , Mori M.
      Nucleic Acids Res.16:8789-8802(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Blood.
    3. 3.
      Lee Y.T. , Miller J.L.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Erythroblast.
    4. 4.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    5. 5.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Liver.
      tissue: Skeletal muscle.
    7. 7.
      "Expression of human liver arginase in Escherichia coli. Purification and properties of the product."
      Ikemoto M. , Tabata M. , Miyake T. , Kono T. , Mori M. , Totani M. , Murachi T.
      Biochem. J.270:697-703(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-13;SUBUNIT
      tissue: Liver.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response."
      Di Costanzo L. , Sabio G. , Mora A. , Rodriguez P.C. , Ochoa A.C. , Centeno F. , Christianson D.W.
      Proc. Natl. Acad. Sci. U.S.A.102:13058-13063(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.29 ANGSTROMS) IN COMPLEX WITH MANGANESE IONS AND THE SYNTHETIC INHIBITOR 2(S)-AMINO-6-BORONOHEXANOIC ACID;SUBCELLULAR LOCATION;SUBUNIT
    10. 10.
      "Expression, purification, assay, and crystal structure of perdeuterated human arginase I."
      Di Costanzo L. , Moulin M. , Haertlein M. , Meilleur F. , Christianson D.W.
      Arch. Biochem. Biophys.465:82-89(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) IN COMPLEX WITH MANGANESE IONS AND THE SYNTHETIC INHIBITOR 2(S)-AMINO-6-BORONOHEXANOIC ACID;IDENTIFICATION BY MASS SPECTROMETRY
    11. 11.
      "Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster."
      Di Costanzo L. , Pique M.E. , Christianson D.W.
      J. Am. Chem. Soc.129:6388-6389(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) IN COMPLEX WITH MANGANESE IONS AND THIOSEMICARBAZIDE;SUBUNIT
    12. 12.
      "Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I."
      Zakharian T.Y. , Di Costanzo L. , Christianson D.W.
      Org. Biomol. Chem.6:3240-3243(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS) IN COMPLEX WITH MANGANESE IONS AND THE SYNTHETIC INHIBITOR (2S)-2-AMINO-7,8-EPOXYOCTANOIC ACID
    13. 13.
      "Three novel mutations in the liver-type arginase gene in three unrelated Japanese patients with argininemia."
      Uchino T. , Haraguchi Y. , Aparicio J.M. , Mizutani N. , Higashikawa M. , Naitoh H. , Mori M. , Matsuda I.
      Am. J. Hum. Genet.51:1406-1412(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARGIN ARG-235
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-290
    15. 15.
      "Molecular basis of phenotypic variation in patients with argininemia."
      Uchino T. , Snyderman S.E. , Lambert M. , Qureshi I.A. , Shapira S.K. , Sansaricq C. , Smit L.M.E. , Jakobs C. , Matsuda I.
      Hum. Genet.96:255-260(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARGIN THR-11 AND VAL-138
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