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Index > Protein center > AKR7L(Gene name) > Human
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  • AKR7L (Gene name),
  • Aflatoxin B1 aldehyde reductase member 4 (Protein name ),  ARK74_HUMAN from NCBI database.
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    • Gene name:
    AKR7L(AFAR3;AKR7A4);
    Protein name:
    Aflatoxin B1 aldehyde reductase member 4;
    Alternative:
    Aldoketoreductase 7-like;AFB1 aldehyde reductase 3(AFB1-AR 3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    331
    Sequence:
    50:
    MSRQLSRARP | ATVLGAMEMG | RRMDAPTSAA | VTRAFLERGH | TEIDTAFLYS | 
    100:
    DGQSETILGG | LGLRMGSSDC | RVKIATKANP | WIGNSLKPDS | VRSQLETSLK | 
    150:
    RLQCPUVDLF | YLHAPDHSAP | VEETLRACHQ | LHQEGKFVEL | GLSNYAAWEV | 
    200:
    AEICTLCKSN | GWILPTVYQG | MYSATTRQVE | TELFPCLRHF | GLRFYAYNPL | 
    250:
    AGGLLTGKYK | YEDKDGKQPV | GRFFGTQWAE | IYRNHFWKEH | HFEGIALVEK | 
    300:
    ALQAAYGASA | PSMTSAALRW | MYHHSQLQGA | HGDAVILGMS | SLEQLEQNLA | 
    331:
    AAEEGPLEPA | VVDAFNQAWH | LFAHECPNYF | I
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Q8NHP1
    Pfam:
    PF00248
    UniGene:
    Hs.662342
    SMR:
    Q8NHP1
    MIM:
    608478
    KEGG:
    hsa:246181
    Uniprot:
    Q8NHP1
     
    FOR
    ELISA Kit for Human Aflatoxin B1 aldehyde reductase member 4
    CLIA Kit for Human Aflatoxin B1 aldehyde reductase member 4
    Polyclonal Antibody for Human Aflatoxin B1 aldehyde reductase member 4
    Monoclonal Antibody for Human Aflatoxin B1 aldehyde reductase member 4
    Protein for Human Aflatoxin B1 aldehyde reductase member 4

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Colon.
    3. 3.
      "Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells."
      Praml C. , Savelyeva L. , Schwab M.
      Oncogene22:4765-4773(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 73-331;VARIANT THR-255;TISSUE SPECIFICITY;PROBABLE SELENOCYSTEINE AT SEC-106
      tissue: Uterus.
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