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Index > Protein center > ASL(Gene name) > Human
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  • ASL (Gene name),
  • Argininosuccinate lyase (Protein name ),  ARLY_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ASL;
    Protein name:
    Argininosuccinate lyase(ASAL);
    Alternative:
    Arginosuccinase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    464
    Sequence:
    50:
    MASESGKLWG | GRFVGAVDPI | MEKFNASIAY | DRHLWEVDVQ | GSKAYSRGLE | 
    100:
    KAGLLTKAEM | DQILHGLDKV | AEEWAQGTFK | LNSNDEDIHT | ANERRLKELI | 
    150:
    GATAGKLHTG | RSRNDQVVTD | LRLWMRQTCS | TLSGLLWELI | RTMVDRAEAE | 
    200:
    RDVLFPGYTH | LQRAQPIRWS | HWILSHAVAL | TRDSERLLEV | RKRINVLPLG | 
    250:
    SGAIAGNPLG | VDRELLRAEL | NFGAITLNSM | DATSERDFVA | EFLFWASLCM | 
    300:
    THLSRMAEDL | ILYCTKEFSF | VQLSDAYSTG | SSLMPQKKNP | DSLELIRSKA | 
    350:
    GRVFGRCAGL | LMTLKGLPST | YNKDLQEDKE | AVFEVSDTMS | AVLQVATGVI | 
    400:
    STLQIHQENM | GQALSPDMLA | TDLAYYLVRK | GMPFRQAHEA | SGKAVFMAET | 
    450:
    KGVALNQLSL | QELQTISPLF | SGDVICVWDY | GHSVEQYGAL | GGTARSSVDW | 
    464:
    QIRQVRALLQ | AQQA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    KEGG:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human ASAL
    Cat.:
    E15356m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human ASAL
    Cat.:
    E15356h
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    Packing:
    96T
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    ELISA Kit for Human ASAL
    Cat.:
    E15356r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human ASAL
    Cat.:
    E15356b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ASAL
    Cat.:
    U15356h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ASAL
    Cat.:
    U15356m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ASAL
    Cat.:
    U15356r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ASAL
    Cat.:
    U15356b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ASAL
    Cat.:
    P15356Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ASAL
    Cat.:
    P15356Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ASAL
    Cat.:
    P15356Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ASAL
    Monoclonal Antibody for Human ASAL
    Monoclonal Antibody for Human ASAL
    Monoclonal Antibody for Human ASAL
    Monoclonal Antibody for Human ASAL
    Protein for Human ASAL
    Protein for Human ASAL
    Protein for Human ASAL
    Protein for Human ASAL

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation of cDNA clones of human argininosuccinate lyase and corrected amino acid sequence."
      Matuo S. , Tatsuno M. , Kobayashi K. , Saheki T. , Miyata T.
      FEBS Lett.234:395-399(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    2. 2.
      "Cloning and sequence analysis of cDNA for human argininosuccinate lyase."
      O'Brien W.E. , McInnes R. , Kalumuck K. , Adcock M.
      Proc. Natl. Acad. Sci. U.S.A.83:7211-7215(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "cDNA sequence, interspecies comparison, and gene mapping analysis of argininosuccinate lyase."
      Todd S. , McGill J.R. , McCombs J.L. , Moore C.M. , Weider I. , Naylor S.L.
      Genomics4:53-59(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    4. 4.
      "Cloning and sequence analysis of cDNA for human argininosuccinate lyase."
      Matuo S.
      Kagoshima Daigaku Igaku Zasshi40:147-160(1988)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      "Complete sequence of the human ASL gene."
      Linnebank M. , Tschiedel E. , Koch H.G.
      Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    6. 6.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
      tissue: Cervix.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 5-97 (ISOFORM 1/2/3)
    9. 9.
      "Regulation of cellular metabolism by protein lysine acetylation."
      Zhao S. , Xu W. , Jiang W. , Yu W. , Lin Y. , Zhang T. , Yao J. , Zhou L. , Zeng Y. , Li H. , Li Y. , Shi J. , An W. , Hancock S.M. , He F. , Qin L. , Chin J. , Yang P. , more...
      Science327:1000-1004(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-69 AND LYS-288;ENZYME REGULATION;MUTAGENESIS OF LYS-288;IDENTIFICATION BY MASS SPECTROMETRY
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Human argininosuccinate lyase: a structural basis for intragenic complementation."
      Turner M.A. , Simpson A. , McInnes R.R. , Howell P.L.
      Proc. Natl. Acad. Sci. U.S.A.94:9063-9068(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (4.2 ANGSTROMS)
      tissue: Liver.
    12. 12.
      "Three-dimensional structure of the argininosuccinate lyase frequently complementing allele Q286R."
      Sampaleanu L.M. , Vallee F. , Thompson G.D. , Howell P.L.
      Biochemistry40:15570-15580(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF VARIANT ARG-286
    13. 13.
      "Analysis of naturally occurring and site-directed mutations in the argininosuccinate lyase gene."
      Barbosa P. , Cialkowski M. , O'Brien W.E.
      J. Biol. Chem.266:5286-5290(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARGINSA TRP-111; GLN-193 AND ARG-286;MUTAGENESIS
    14. 14.
      "Molecular analysis of human argininosuccinate lyase: mutant characterization and alternative splicing of the coding region."
      Walker D.C. , McCloskey D.A. , Simard L.R. , McInnes R.R.
      Proc. Natl. Acad. Sci. U.S.A.87:9625-9629(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARGINSA CYS-95
    15. 15.
      "Clinical, enzymatic, and molecular genetic characterization of a biochemical variant type of argininosuccinic aciduria: prenatal and postnatal diagnosis in five unrelated families."
      Kleijer W.J. , Garritsen V.H. , Linnebank M. , Mooyer P. , Huijmans J.G.M. , Mustonen A. , Simola K.O.J. , Arslan-Kirchner M. , Battini R. , Briones P. , Cardo E. , Mandel H. , Tschiedel E. , Wanders R.J.A. , Koch H.G.
      J. Inherit. Metab. Dis.25:399-410(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARGINSA MET-178; CYS-379 AND CYS-385
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] SER-181 AND VAL-200
    17. 17.
      "Argininosuccinate lyase deficiency: mutational spectrum in Italian patients and identification of a novel ASL pseudogene."
      Trevisson E. , Salviati L. , Baldoin M.C. , Toldo I. , Casarin A. , Sacconi S. , Cesaro L. , Basso G. , Burlina A.B.
      Hum. Mutat.28:694-702(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARGINSA ASN-31; GLN-113; MET-178; GLN-186; TRP-236; ARG-286; LEU-335; ARG-382 AND TRP-456
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