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Index > Protein center > Asb6(Gene name) > Mouse
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  • Asb6 (Gene name),
  • Ankyrin repeat and SOCS box protein 6 (Protein name ),  ASB6_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Asb6;
    Protein name:
    Ankyrin repeat and SOCS box protein 6(ASB-6);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds APS. Identified in a complex with TCEB1 and TCEB2. Interacts with CUL5 and RNF7.
    Function:
    Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    418
    Sequence:
    50:
    MPFLHGFRRI | IFEYQPLVDA | ILGALGIQDL | ERQEPLDDSA | SSEESRILVL | 
    100:
    TELLEQKAHS | PFYQEGVSNA | LLKMAELGLT | RAAAVLLQSG | ANLNFEDPVT | 
    150:
    YYTALHIAVL | RNQPDMVELL | VRHGADINRR | DRIHESSPLD | LASEEPERLP | 
    200:
    CLQRLLDLGA | DVNAADKNGK | TALLHALASS | DGVQIHNTEN | IRLLLEGGAD | 
    250:
    VKATTKDGDT | VFTCIIFLLG | ETVCGDKEEA | PMINRFCFQV | TQLLLAHGAD | 
    300:
    PSECPAHESL | THICLKSFKL | HFPLLCFLLE | SGAAYNCSLH | GASCWSGFNL | 
    350:
    VFERLCSHPG | CAEDDSHIEL | LHKAETVLDL | MVTSSQRLQL | PENLNIHPVG | 
    400:
    SLAGKIQALH | ASLRQLESYP | PPLKHLCRVS | IRLCLRPWPV | DTKVKALPLP | 
    418:
    DRLKWYLLSA | HSDTQDTC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ASB-6
    ELISA Kit for Mouse ASB-6
    CLIA Kit for Mouse ASB-6
    CLIA Kit for Mouse ASB-6
    Polyclonal Antibody for Mouse ASB-6
    Polyclonal Antibody for Mouse ASB-6
    Monoclonal Antibody for Mouse ASB-6
    Monoclonal Antibody for Mouse ASB-6
    Protein for Mouse ASB-6
    Protein for Mouse ASB-6

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Functional analysis of Asb-1 using genetic modification in mice."
      Kile B.T. , Metcalf D. , Mifsud S. , DiRago L. , Nicola N.A. , Hilton D.J. , Alexander W.S.
      Mol. Cell. Biol.21:6189-6197(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex."
      Wilcox A. , Katsanakis K.D. , Bheda F. , Pillay T.S.
      J. Biol. Chem.279:38881-38888(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH APS;IDENTIFICATION IN A COMPLEX CONTAINING TCEB1 AND TCEB2;TISSUE SPECIFICITY
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